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Myristic Acid (CID 11005) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(747)
 
 
Inconclusive(55)
 
 
Unspecified(59)
 
 
Top Targets:
7tm 4(34)
 
 
NR LBD PPAR(29)
 
 
 
 
NR LBD AR(18)
 
 
 
NR LBD ER(18)
 
 
 
NR LBD TR(14)
 
 
 
BioAssay Types:
Confirmatory(415)
 
 
 
 
 
Screening(293)
 
 
 
Literature(82)
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(402)
 
 
 
 
 
IC50(15)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 689    Data Row: 868   Total Pages: 44   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103329704]
IC50 5Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cells [AID261940, Type: Literature]Toll-like receptor 2 [gi:20140434]
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2
[SID103329704]
IC50 5.4Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay [AID1114584, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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3
[SID103329704]
IC50 21Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay [AID1114583, Type: confirmatory]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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4
[SID17389652]
Potency 22.3872qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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5
[SID103329704]
IC50 24Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay [AID1114582, Type: confirmatory]Peroxisome proliferator-activated receptor delta [gi:417522]
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6
[SID144213098]
Ratio Potency (uM) 51.874qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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7
[SID56436661]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID492953, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
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8
[SID103329704]
IC50 100Concentration required against dynamin-1 GTPase activity of sheep brain. [AID63727, Type: Literature]
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9
[SID103329704]
IC50 500Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360927, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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10
[SID103329704]
IC50 500Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360928, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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11
[SID103329704]
Specific activity of expressed human recombinant UGT1A10 [AID624613, Type: Literature]UDP-glucuronosyltransferase 1-10 [gi:29839636]
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12
[SID103329704]
Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
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13
[SID103329704]
Antibacterial activity against Staphylococcus aureus [AID264976, Type: Literature]
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14
[SID103329704]
Antibacterial activity against Micrococcus luteus [AID264977, Type: Literature]
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15
[SID103329704]
Antibacterial activity against Escherichia coli [AID264978, Type: Literature]
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16
[SID103329704]
Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined at 2 x 10E-4 M [AID40631, Type: Literature]
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17
[SID103329704]
Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
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18
[SID103329704]
Inhibition of aromatase in human placental microsomes at 20 ug/ml by radiometric method relative to control [AID376615, Type: Literature]Aromatase [gi:117293]
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19
[SID56436661]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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20
[SID103329704]
Antibacterial activity against Staphylococcus aureus by broth microdilution method [AID597407, Type: Literature]
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