STK359789 (CID 1084214) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(641)
 
 
Inconclusive(15)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(10)
 
 
Tryp SPc(8)
 
 
BioAssay Types:
Screening(461)
 
 
 
 
 
Confirmatory(184)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(127)
 
 
 
 
IC50(39)
 
 
EC50(13)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 660    Data Row: 665   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14723253]
EC50 0.162Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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2
[SID14723253]
EC50 0.162Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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3
[SID14723253]
EC50 0.162Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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4
[SID14723253]
EC50 0.162Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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5
[SID126920241]
EC50 0.188Counter screen for HTS for Beta-2AR agonists with FAP-tagged human CCR5 with Powderset2 [AID651728, Type: confirmatory]CCR5 [Homo sapiens] [gi:289466095]
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6
[SID85303500]
EC50 0.391Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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7
[SID85303500]
EC50 0.391Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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8
[SID85303500]
EC50 0.391Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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9
[SID85303500]
EC50 0.391Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
10
[SID126920241]
EC50 1.37Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2 [AID623882, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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11
[SID126920241]
EC50 1.37Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2 [AID623882, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
12
[SID126920241]
EC50 1.37Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2 [AID623882, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
13
[SID126920241]
EC50 1.37Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2 [AID623882, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
14
[SID14723253]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
15
[SID14723253]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
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16
[SID14723253]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
17
[SID14723253]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
18
[SID85303500]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
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19
[SID85303500]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
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20
[SID85303500]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
21
[SID85303500]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
22
[SID14723253]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
23
[SID14723253]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
24
[SID14723253]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
25
[SID14723253]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
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26
[SID14723253]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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27
[SID14723253]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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28
[SID14723253]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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29
[SID14723253]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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30
[SID14723253]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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31
[SID14723253]
Potency 14.1254qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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32
[SID14723253]
Potency 35.4813qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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33
[SID14723253]
 Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
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34
[SID14723253]
 Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
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35
[SID14723253]
 Full deck counterscreen for antagonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective inhibitors and assay artifacts using the parental CHOK1 cell line [AID602250, Type: screening]
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36
[SID14723253]
 uHTS luminescent assay for identification of compounds that enhance the survival of human induced pluripotent stem cells when cultured as single cells [AID602274, Type: screening]
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37
[SID14723253]
 HTS for suppressors of simvastatin-induced mytoxicity in differentiated C2C12 cells Measured in Cell-Based System Using Plate Reader - 2112-01_Suppressor_SinglePoint_HTS_Activity [AID602340, Type: screening]
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38
[SID14723253]
 Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Inhibitor_SinglePoint_HTS_Activity [AID602342, Type: screening]
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39
[SID14723253]
 Whole cell Yeast HTS to identify compounds modulating the fidelity of the start codon recognition in eukaryotes. Measured in Whole Organism System Using Plate Reader - 2155-01_Other_SinglePoint_HTS_Activity [AID602363, Type: screening]
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40
[SID14723253]
 uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
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41
[SID14723253]
 Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Activator_SinglePoint_HTS_Activity [AID623901, Type: screening]
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42
[SID14723253]
 HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening]
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43
[SID14723253]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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44
[SID14723253]
 Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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45
[SID14723253]
 DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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46
[SID14723253]
 HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
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47
[SID14723253]
 Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
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48
[SID14723253]
 MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Activator_SinglePoint_HTS_Activity [AID651723, Type: screening]
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49
[SID14723253]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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50
[SID14723253]
 Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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