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4,6-dinitro-o-cresol (CID 10800) - Compound BioActivity Data
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BioActivity Outcomes:
Active(55)
 
 
Inactive(223)
 
 
Inconclusive(119)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
 
NR LBD AR(18)
 
 
 
 
NR LBD TR(14)
 
 
 
 
NR LBD VDR(12)
 
 
 
BioAssay Types:
Confirmatory(315)
 
 
 
 
Summary(48)
 
 
 
 
Literature(7)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(315)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 262    Data Row: 400   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144214029]
Potency-Replicate_1 0.6094qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144210645]
Potency-Replicate_1 0.6859qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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3
[SID144210645]
Ratio Potency (uM) 0.830982qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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4
[SID144214029]
Potency-Replicate_1 1.23qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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5
[SID144214029]
Potency-Replicate_1 1.7229qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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6
[SID144214029]
Ratio Potency (uM) 2.23442qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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7
[SID144210645]
Potency-Replicate_1 4.3277qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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8
[SID144214029]
Potency-Replicate_1 4.8558qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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9
[SID144214029]
Potency-Replicate_1 4.8966qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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10
[SID144210645]
Ratio Potency (uM) 8.30982qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
11
[SID144210645]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144214029]
Potency-Replicate_1 10.8707qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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13
[SID144214029]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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14
[SID144214029]
Ratio Potency (uM) 12.8989qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
15
[SID17389567]
Potency 13.3332qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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16
[SID144214029]
Potency-Replicate_1 13.6437qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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17
[SID144214029]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID144214029]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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19
[SID144210645]
Potency-Replicate_1 15.3553qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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20
[SID144214029]
Potency-Replicate_1 15.3553qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View