Bookmark and Share
2-Acetyl-3-(4-bromo-phenyl)-[1,4]naphthoquinone (CID 1072148) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(111)
 
 
Inactive(573)
 
 
Inconclusive(38)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(47)
 
 
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
NR LBD PPAR(6)
 
 
BioAssay Types:
Screening(465)
 
 
 
 
 
Confirmatory(234)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(155)
 
 
 
 
 
IC50(42)
 
 
 
 
 
EC50(18)
 
 
 
 
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 661    Data Row: 725   Total Pages: 37   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17509055]
Potency 0.2812qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
View
2
[SID17509055]
AbsAC35_uM 0.472Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
View
3
[SID17509055]
AbsAC35_uM 0.82Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity [AID652047, Type: confirmatory]
View
4
[SID17509055]
Absolute IC50 (XBP1) 0.99XBP1 DR counterscreen for CHOP [AID504313, Type: confirmatory]XBP1 [Homo sapiens] [gi:47678753]
View
5
[SID17509055]
EC50 1.002Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
View
6
[SID17509055]
AC50_uM 1.057Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
View
7
[SID17509055]
Potency 1.2995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
8
[SID17509055]
EC50 1.449Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
View
9
[SID17509055]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
10
[SID17509055]
EC50 1.814High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Dose Response [AID1045, Type: confirmatory]
View
11
[SID17509055]
EC50_uM 1.94Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
12
[SID17509055]
EC50 1.983High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Dose Response [AID1047, Type: confirmatory]
View
13
[SID17509055]
EC50 2.013Luminescence Cell-Based/Microorganism Dose Confirmation HTS to Identify Inhibitors of T.Cruzi Replication. [AID2044, Type: confirmatory]
View
14
[SID17509055]
EC50 2.421Luminescence Cell-Based Dose Response HTS Screen to Identify Cytotoxic Compounds of NIH3T3 cells. [AID2010, Type: confirmatory]
View
15
[SID17509055]
Potency 2.5119qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
16
[SID17509055]
AbsAC1000_uM 2.615In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_Dose_CherryPick_Activity [AID540271, Type: confirmatory]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
View
17
[SID17509055]
Potency 2.9093qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Beta-Lactamase Assay [AID602202, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
18
[SID17509055]
AC50_uM 3.045Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
19
[SID17509055]
IC50 3.1343HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate [AID1220, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
View
20
[SID17509055]
EC50_uM 3.14Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View