Riboflavin (CID 1072) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(15)
 
 
Inactive(207)
 
 
Inconclusive(33)
 
 
Unspecified(4)
 
 
Top Targets:
HELICc(7)
 
 
 
 
Peptidase C1A(6)
 
 
PLN02808(6)
 
 
NR LBD TR(6)
 
 
NR LBD ROR li..(6)
 
 
BioAssay Types:
Confirmatory(163)
 
 
 
 
Literature(69)
 
 
 
 
 
Screening(13)
 
 
 
BioActivity Types:
Potency(157)
 
 
 
 
Ki(2)
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 106    Data Row: 259   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104171347]
Potency 7.5686Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID26753745]
Potency 12.5893qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
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3
[SID26753745]
Potency 12.5893qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
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4
[SID104171347]
Potency 13.4591Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID26749054]
Potency 15.8489qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
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6
[SID103615906]
IC50 20Inhibition of Escherichia coli N5-CAIR synthetase by phosphate assay [AID350914, Type: Literature]
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7
[SID104171347]
Potency 31.6228Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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8
[SID29215176]
Potency 35.4813qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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9
[SID29215176]
Potency 44.6684Counterscreen for RECQ1 Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2711, Type: confirmatory]
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10
[SID29215176]
Potency 44.6684Counterscreen for BLMA Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2712, Type: confirmatory]
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11
[SID29215176]
Potency 112.202Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2708, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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12
[SID26749054]
 qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
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13
[SID26753745]
 qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
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14
[SID29215176]
 qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
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15
[SID26753745]
 qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen [AID2472, Type: screening]glyceraldehyde-3-phosphate dehydrogenase [Homo sapiens] [gi:7669492]
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16
[SID26753745]
 qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen [AID2472, Type: screening]glyceraldehyde-3-phosphate dehydrogenase [Homo sapiens] [gi:7669492]
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17
[SID103615906]
Ki 81Inhibition of Escherichia coli N5-CAIR synthetase using variable amount of aminoimidazole ribomucleotide and fixed ATP by ATPase assay [AID350915, Type: Literature]
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18
[SID103615906]
Ki 122Inhibition of Escherichia coli N5-CAIR synthetase using variable amount of ATP and fixed aminoimidazole ribomucleotide by ATPase assay [AID350916, Type: Literature]
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19
[SID29215176]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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20
[SID104171347]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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21
[SID26749054]
Potency 10qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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22
[SID26749054]
Potency 10qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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23
[SID104171347]
Potency 12.5797S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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24
[SID26532590]
 Luminescence-based primary cell-based high throughput screening assay to identify inhibitors of NADPH oxidase 1 (Nox1): Maybridge Library [AID1792, Type: screening]NADPH oxidase 1 [Homo sapiens] [gi:83699673]
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25
[SID26532590]
 Luminescence-based primary cell-based high throughput screening assay to identify inhibitors of NADPH oxidase 1 (Nox1): Maybridge Library [AID1792, Type: screening]NADPH oxidase 1 [Homo sapiens] [gi:83699673]
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26
[SID26532590]
 Primary Cell Based High Throughput Screening Assay for Agonists of GALR2 [AID833, Type: screening]galanin receptor type 2 [Rattus norvegicus] [gi:2578455]
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27
[SID26532590]
 Primary Cell Based High Throughput Screening Assay for Agonists of GALR2 [AID833, Type: screening]galanin receptor type 2 [Rattus norvegicus] [gi:2578455]
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28
[SID104171347]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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29
[SID104171347]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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30
[SID29215176]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
View
31
[SID29215176]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
View
32
[SID26532590]
 Fluorescence polarization-based Maybridge primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase Methylesterase 1 (PME-1). [AID2291, Type: screening]protein phosphatase methylesterase 1 [Homo sapiens] [gi:7706645]
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33
[SID104171347]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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34
[SID104171347]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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35
[SID124882975]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
36
[SID124882975]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
37
[SID124882977]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
38
[SID124882977]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
39
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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40
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
41
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
42
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
43
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
44
[SID124882975]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
45
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
46
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
47
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
48
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
49
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
50
[SID124882977]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View