Bookmark and Share
Dihydrotestosterone (CID 10635) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(125)
 
 
Inactive(737)
 
 
Inconclusive(108)
 
 
Unspecified(274)
 
 
Top Targets:
NR LBD AR(114)
 
 
 
 
 
7TM GPCR Srx(31)
 
 
 
NR LBD ER(30)
 
 
 
 
 
7TM GPCR Srsx(29)
 
 
 
NR LBD PPAR(24)
 
 
 
BioAssay Types:
Confirmatory(575)
 
 
 
 
 
Literature(294)
 
 
 
 
 
Screening(270)
 
 
 
Summary(63)
 
 
 
 
BioActivity Types:
Potency(461)
 
 
 
 
 
IC50(168)
 
 
 
 
 
EC50(25)
 
 
 
Ki(19)
 
 
 
Kd(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 946    Data Row: 1244   Total Pages: 63   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123099348]
EC50 5e-05Agonist activity at androgen receptor expressed in mouse C2C12 cells assessed as osteoblast differentiation after 5 days [AID569780, Type: confirmatory]
View
2
[SID123099348]
IC50 5e-05Activity at androgen receptor in human Saos2 cells assessed as IL6 repression [AID319592, Type: Literature]Androgen receptor [gi:113830]
View
3
[SID123099348]
Kd 0.000182Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin [AID318680, Type: Literature]Sex hormone-binding globulin [gi:134907]
View
4
[SID123099348]
Ki 0.0002Binding affinity to human AR [AID293945, Type: Literature]Androgen receptor [gi:113830]
View
5
[SID123099348]
Ki 0.0002Binding affinity to human AR [AID298549, Type: Literature]Androgen receptor [gi:113830]
View
6
[SID123099348]
Ki 0.0002Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assay [AID319591, Type: Literature]Androgen receptor [gi:113830]
View
7
[SID123099348]
Ki 0.0002Displacement of [3H]DHT from human androgen receptor expressed in MDA-MB-453 cells by whole cell receptor binding assay [AID272949, Type: Literature]Androgen receptor [gi:113830]
View
8
[SID123099348]
Ki 0.0002Binding affinity to human androgen receptor expressed in CV1 cells [AID290231, Type: Literature]Androgen receptor [gi:113830]
View
9
[SID123099348]
Ki 0.00027Binding affinity to rat androgen receptor by competitive inhibition assay [AID348771, Type: Literature]Androgen receptor [gi:113832]
View
10
[SID123099348]
Ki 0.0003Displacement of [3H]DHT from human AR in MDA453 cells [AID274601, Type: Literature]Androgen receptor [gi:113830]
View
11
[SID123099348]
Ki 0.0003Displacement of [3H]DHT from human AR expressed in MDA-MB-453 cells [AID286658, Type: Literature]Androgen receptor [gi:113830]
View
12
[SID123099348]
Ki 0.00069Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone [AID39296, Type: Literature]Androgen receptor [gi:113832]
View
13
[SID123099348]
Ki 0.0009Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cells [AID331664, Type: Literature]Androgen receptor [gi:113830]
View
14
[SID46392350]
Kd 0.0009Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, The Structure Of The N-Terminal Lg Domain Of Shbg In Crystals Soaked With Edta [gi:21465817]
View
15
[SID46392350]
Kd 0.0009Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, The Structure Of The N-Terminal Lg Domain Of Shbg In Crystals Soaked With Edta [gi:21465817]
View
16
[SID144204607]
Potency-Replicate_1 0.0009qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
17
[SID123099348]
EC50 0.00097Agonist activity at rat androgen receptor [AID626471, Type: Literature]Androgen receptor [gi:113832]
View
18
[SID123099348]
IC50 0.001Displacement of [3H]methyltrienolone from androgen receptor in human MDA-MB-453 cells [AID429503, Type: Literature]Androgen receptor [gi:113830]
View
19
[SID123099348]
IC50 0.001Displacement of [3H] ]5alpha-DHT from mouse androgen receptor expressed in monkey COS7 cells after 2 hrs by scintillation counting analysis [AID733361, Type: Literature]Androgen receptor [gi:113831]
View
20
[SID123099348]
EC50 0.00126Agonist activity at androgen receptor LBD T877A mutant in mouse NIH3T3 cells transiently transfected with beta-galactosidase reporter gene assessed as cellular transformation by R-SAT assay [AID445835, Type: Literature]
View