Bookmark and Share

BioActivity Data for Compound Dihydrotestosterone (CID 10635)

BioActivity Outcomes:
Active(122)
 
 
Inactive(700)
 
 
Inconclusive(70)
 
 
Unspecified(280)
 
 
Top Targets:
NR LBD AR(112)
 
 
 
 
 
7tm 4(60)
 
 
 
NR LBD ER(23)
 
 
 
 
 
p450(18)
 
 
 
 
 
NR LBD PPAR(16)
 
 
 
BioAssay Types:
Confirmatory(513)
 
 
 
 
 
Literature(303)
 
 
 
 
 
Screening(272)
 
 
 
Summary(39)
 
 
 
 
BioAssay Categories:
In vitro(16)
 
 
 
In vivo(3)
 
 
 
Biochemical(139)
 
 
 
 
Toxicity(56)
 
 
 
 
 
ADME(8)
 
 
 
Cell-based(109)
 
 
 
 
Organism-base..(7)
 
 
BioActivity Types:
Potency(381)
 
 
 
 
 
IC50(171)
 
 
 
 
 
EC50(26)
 
 
 
Ki(19)
 
 
 
Kd(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 957    Data Row: 1172   Total Pages: 59   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123099348]
EC50 5e-05Agonist activity at androgen receptor expressed in mouse C2C12 cells assessed as osteoblast differentiation after 5 days [AID569780, Type: Literature]
View
2
[SID123099348]
IC50 5e-05Activity at androgen receptor in human Saos2 cells assessed as IL6 repression [AID319592, Type: Literature]Androgen receptor [gi:113830]
View
3
[SID123099348]
Kd 0.000182Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin [AID318680, Type: Literature]Sex hormone-binding globulin [gi:134907]
View
4
[SID208011826]
Kd 0.000182Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
View
5
[SID208011826]
Kd 0.000182Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
View
6
[SID123099348]
Ki 0.0002Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assay [AID319591, Type: Literature]Androgen receptor [gi:113830]
View
7
[SID123099348]
Ki 0.0002Displacement of [3H]DHT from human androgen receptor expressed in MDA-MB-453 cells by whole cell receptor binding assay [AID272949, Type: Literature]Androgen receptor [gi:113830]
View
8
[SID123099348]
Ki 0.0002Binding affinity to human androgen receptor expressed in CV1 cells [AID290231, Type: Literature]Androgen receptor [gi:113830]
View
9
[SID123099348]
Ki 0.0002Binding affinity to human AR [AID293945, Type: Literature]Androgen receptor [gi:113830]
View
10
[SID123099348]
Ki 0.0002Binding affinity to human AR [AID298549, Type: Literature]Androgen receptor [gi:113830]
View
11
[SID123099348]
Ki 0.00027Binding affinity to rat androgen receptor by competitive inhibition assay [AID348771, Type: Literature]Androgen receptor [gi:113832]
View
12
[SID123099348]
Ki 0.0003Displacement of [3H]DHT from human AR expressed in MDA-MB-453 cells [AID286658, Type: Literature]Androgen receptor [gi:113830]
View
13
[SID123099348]
Ki 0.0003Displacement of [3H]DHT from human AR in MDA453 cells [AID274601, Type: Literature]Androgen receptor [gi:113830]
View
14
[SID123099348]
Ki 0.00069Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone [AID39296, Type: Literature]Androgen receptor [gi:113832]
View
15
[SID123099348]
Ki 0.0009Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cells [AID331664, Type: Literature]Androgen receptor [gi:113830]
View
16
[SID46392350]
Kd 0.0009Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, The Structure Of The N-Terminal Lg Domain Of Shbg In Crystals Soaked With Edta [gi:21465817]
View
17
[SID46392350]
Kd 0.0009Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, The Structure Of The N-Terminal Lg Domain Of Shbg In Crystals Soaked With Edta [gi:21465817]
View
18
[SID144204607]
Potency-Replicate_1 0.0009qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
19
[SID123099348]
EC50 0.00097Agonist activity at rat androgen receptor [AID626471, Type: Literature]Androgen receptor [gi:113832]
View
20
[SID123099348]
IC50 0.001Displacement of [3H] ]5alpha-DHT from mouse androgen receptor expressed in monkey COS7 cells after 2 hrs by scintillation counting analysis [AID733361, Type: Literature]Androgen receptor [gi:113831]
View