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CHEMBL152394 (CID 10595354) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Unspecified(4)
 
 
Top Targets:
Pyr redox dim(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
IC50(2)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103400495]
IC50 6Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 uM T(S)2. [AID212727, Type: Literature]Trypanothione reductase [gi:136620]
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2
[SID103400495]
ED50 12.5In vitro antiparasitic activity against Leishmania infantum was tested using sigmoidal regression analysis [AID100890, Type: Literature]
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3
[SID103400495]
ED50 12.5In vitro antiparasitic activity against Trypanosoma brucei was tested by sigmoidal regression analysis [AID208234, Type: Literature]
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4
[SID103400495]
ED50 12.5In vitro antiparasitic activity against Trypanosoma cruzi was tested by sigmoidal regression analysis [AID208235, Type: Literature]
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5
[SID103400495]
IC50 220Rate of NADPH oxidation by TcTR in presence of 100 uM NQ was determined in comparison to intrinsic oxidase activity [AID212728, Type: Literature]
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