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BioActivity Data for Compound Pyridoxine (CID 1054)

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BioActivity Outcomes:
Active(6)
 
 
Inactive(286)
 
 
Inconclusive(15)
 
 
Unspecified(35)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
 
p450(13)
 
 
NR LBD GR(10)
 
 
 
BioAssay Types:
Confirmatory(236)
 
 
 
 
Summary(48)
 
 
 
Literature(38)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(243)
 
 
 
 
AC50(3)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 243    Data Row: 342   Total Pages: 18   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103450438]
Km 9.9Activity at human PKH kinase expressed in Escherichia coli by affinity chromatography [AID464423, Type: Literature]Pyridoxal kinase [gi:2811007]
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2
[SID144207193]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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3
[SID103450438]
Increase in seed vigor in Cenchrus americanus cultivar 7042S at 20 mM incubated for 6 hr followed by sowing measured at 7-day old seedling stage relative to control [AID1087753, Type: Literature]
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4
[SID48416500]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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5
[SID11112145]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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6
[SID11112145]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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7
[SID103450438]
Stimulation of seed germination in Cenchrus americanus cultivar 7042S at 20 mM incubated for 6 hr followed by sowing measured at 7-day old seedling stage (Rvb = 88%) [AID1087755, Type: Literature]
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8
[SID103450438]
Proposed mechanism(s) of liver damage. [column 'MEC' in source] [AID1079949, Type: Literature]
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9
[SID103450438]
Induction of systemic acquired resistance against Sclerospora graminicola in Cenchrus americanus cultivar 7042S assessed as protection against downy mildew disease at 20 mM applied to seeds prior to sowing followed by inoculation on 2 day old seedling measured on day 30 in green house conditions (Rvb = 3%) [AID1087752, Type: Literature]
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10
[SID103450438]
Inhibition of linezolid-induced hematological events in bone infection patient assessed as rate of thrombocytopenia at 125 mg relative to control [AID405625, Type: Literature]
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11
[SID103450438]
Inhibition of linezolid-induced hematological events in bone infection patient assessed as rate of anemia at 125 mg relative to control [AID405626, Type: Literature]
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12
[SID103450438]
Percent reduction of ADP (4 uM) induced platelet aggregation was determined at 0.5 mM concentration [AID251387, Type: Literature]
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13
[SID103450438]
Percent reduction of collagen (1 ug/mL) induced platelet aggregation was determined at 0.5 mM concentration [AID251393, Type: Literature]
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14
[SID103450438]
Percent reduction of collagen (5 ug/mL) induced platelet aggregation was determined at 0.5 mM concentration [AID251394, Type: Literature]
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15
[SID103450438]
Percent reduction of thrombin receptor activating peptide (12 uM) induced platelet aggregation was determined at 0.5 mM concentration [AID251419, Type: Literature]
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16
[SID103450438]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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17
[SID103450438]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
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18
[SID11112145]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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19
[SID103450438]
Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] [AID1079943, Type: Literature]
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20
[SID103450438]
Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] [AID1079944, Type: Literature]
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