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BioActivity Data for Compound Pyridoxine (CID 1054)

BioActivity Outcomes:
Active(6)
 
 
Inactive(294)
 
 
Inconclusive(15)
 
 
Unspecified(36)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
p450(13)
 
 
NR LBD GR(10)
 
 
 
BioAssay Types:
Confirmatory(236)
 
 
 
 
Summary(48)
 
 
 
Literature(38)
 
 
 
 
Screening(11)
 
 
BioAssay Categories:
Biochemical(2)
 
 
 
Toxicity(34)
 
 
 
ADME(7)
 
 
Cell-based(8)
 
 
BioActivity Types:
Potency(243)
 
 
 
 
AC50(3)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 252    Data Row: 351   Total Pages: 18   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103450438]
Km 9.9Activity at human PKH kinase expressed in Escherichia coli by affinity chromatography [AID464423, Type: Literature]Pyridoxal kinase [gi:2811007]
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2
[SID144207193]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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3
[SID11112145]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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4
[SID11112145]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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5
[SID48416500]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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6
[SID103450438]
Increase in seed vigor in Cenchrus americanus cultivar 7042S at 20 mM incubated for 6 hr followed by sowing measured at 7-day old seedling stage relative to control [AID1087753, Type: Literature]
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7
[SID103450438]
Stimulation of seed germination in Cenchrus americanus cultivar 7042S at 20 mM incubated for 6 hr followed by sowing measured at 7-day old seedling stage (Rvb = 88%) [AID1087755, Type: Literature]
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8
[SID103450438]
Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 [AID1159387, Type: other]
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9
[SID103450438]
Proposed mechanism(s) of liver damage. [column 'MEC' in source] [AID1079949, Type: Literature]
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10
[SID103450438]
Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] [AID1079948, Type: Literature]
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11
[SID103450438]
Comments (NB not yet translated). [column 'COMMENTAIRES' in source] [AID1079947, Type: Literature]
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12
[SID103450438]
Presence of at least one case with successful reintroduction. [column 'REINT' in source] [AID1079946, Type: Literature]
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13
[SID103450438]
Animal toxicity known. [column 'TOXIC' in source] [AID1079945, Type: Literature]
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14
[SID103450438]
Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] [AID1079944, Type: Literature]
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15
[SID103450438]
Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] [AID1079943, Type: Literature]
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16
[SID103450438]
Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] [AID1079942, Type: Literature]
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17
[SID103450438]
Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] [AID1079941, Type: Literature]
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18
[SID103450438]
Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] [AID1079940, Type: Literature]
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19
[SID103450438]
Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] [AID1079939, Type: Literature]
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20
[SID103450438]
Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] [AID1079938, Type: Literature]
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