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Pyridoxine (CID 1054) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(283)
 
 
Inconclusive(15)
 
 
Unspecified(35)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
 
p450(13)
 
 
NR LBD GR(10)
 
 
 
BioAssay Types:
Confirmatory(233)
 
 
 
 
Summary(48)
 
 
 
Literature(38)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(243)
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 240    Data Row: 339   Total Pages: 17   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103450438]
Km 9.9Activity at human PKH kinase expressed in Escherichia coli by affinity chromatography [AID464423, Type: Literature]Pyridoxal kinase [gi:2811007]
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2
[SID144207193]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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3
[SID103450438]
Increase in seed vigor in Cenchrus americanus cultivar 7042S at 20 mM incubated for 6 hr followed by sowing measured at 7-day old seedling stage relative to control [AID1087753, Type: Literature]
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4
[SID11112145]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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5
[SID11112145]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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6
[SID48416500]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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7
[SID11112145]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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8
[SID103450438]
Percent reduction of ADP (4 uM) induced platelet aggregation was determined at 0.5 mM concentration [AID251387, Type: Literature]
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9
[SID103450438]
Percent reduction of collagen (1 ug/mL) induced platelet aggregation was determined at 0.5 mM concentration [AID251393, Type: Literature]
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10
[SID103450438]
Percent reduction of collagen (5 ug/mL) induced platelet aggregation was determined at 0.5 mM concentration [AID251394, Type: Literature]
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11
[SID103450438]
Percent reduction of thrombin receptor activating peptide (12 uM) induced platelet aggregation was determined at 0.5 mM concentration [AID251419, Type: Literature]
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12
[SID103450438]
Inhibition of linezolid-induced hematological events in bone infection patient assessed as rate of thrombocytopenia at 125 mg relative to control [AID405625, Type: Literature]
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13
[SID103450438]
Inhibition of linezolid-induced hematological events in bone infection patient assessed as rate of anemia at 125 mg relative to control [AID405626, Type: Literature]
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14
[SID103450438]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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15
[SID103450438]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
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16
[SID103450438]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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17
[SID103450438]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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18
[SID103450438]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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19
[SID103450438]
Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in O'Brien data [AID625294, Type: Literature]
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20
[SID103450438]
Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in Pfizer data [AID625295, Type: Literature]
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