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BioActivity Data for Compound U 69593 (CID 105104)

BioActivity Outcomes:
Active(48)
 
 
Inactive(160)
 
 
Inconclusive(43)
 
 
Unspecified(24)
 
 
Top Targets:
7tm 4(15)
 
 
 
 
 
NR LBD PPAR(8)
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Confirmatory(134)
 
 
 
 
Literature(100)
 
 
 
 
 
Summary(28)
 
 
 
Screening(10)
 
 
BioAssay Categories:
In vitro(7)
 
 
Biochemical(30)
 
 
 
 
 
Toxicity(6)
 
 
 
Cell-based(18)
 
 
 
 
 
BioActivity Types:
Potency(145)
 
 
 
 
AC50(6)
 
 
Ki(5)
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 211    Data Row: 275   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103177815]
Ki 0.002Binding affinity towards Mutant D216N, D217N, E218Q Opioid receptor kappa 1 EL-2 expressed in HEK cells [AID141256, Type: Literature]
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2
[SID103177815]
EC50 0.0022Effective concentration required for in vitro agonist potency in guinea-pig ileum myenteric plexus preparation (GPI) [AID73741, Type: confirmatory]
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3
[SID103177815]
Ki 0.0024Binding affinity towards Mutant E203Q, D204N, D206N, Opioid receptor kappa 1 EL-2 expressed in HEK cells [AID141261, Type: Literature]
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4
[SID103177815]
Ki 0.003Binding affinity towards mutant E203Q,D204N,D206N,E209Q Opioid receptor kappa 1 EL-2 expressed in HEK cells [AID141263, Type: Literature]
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5
[SID103177815]
Ki 0.0073Binding affinity for the Opioid receptor kappa 1 [AID149131, Type: Literature]Kappa-type opioid receptor [gi:730228]
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6
[SID103177815]
EC50 0.028Effective concentration required for in vitro evaluation of agonist activity on mouse vas deferens preparation [AID127786, Type: confirmatory]
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7
[SID103177815]
Ki 0.052Binding affinity for the Opioid receptor mu 1 [AID147910, Type: Literature]Mu-type opioid receptor [gi:3024265]
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8
[SID26756545]
Potency 13.4591Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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9
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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10
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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11
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_33, Type: Literature]
View
12
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_34, Type: Literature]
View
13
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_60, Type: Literature]
View
14
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_32, Type: Literature]
View
15
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_46, Type: Literature]
View
16
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
View
17
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_54, Type: Literature]
View
18
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_35, Type: Literature]
View
19
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_23, Type: Literature]
View
20
[SID26756545]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_24, Type: Literature]
View