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AG-205/40649295 (CID 1043575) - Compound BioActivity Data
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BioActivity Outcomes:
Active(27)
 
 
Inactive(771)
 
 
Inconclusive(25)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(19)
 
 
alkPPc(14)
 
 
Tryp SPc(13)
 
 
Bcl-2 like(12)
 
 
BioAssay Types:
Screening(542)
 
 
 
 
 
Confirmatory(254)
 
 
 
 
 
Literature(16)
 
 
 
BioActivity Types:
Potency(177)
 
 
 
 
 
IC50(46)
 
 
 
EC50(16)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 754    Data Row: 826   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID174494701]
EC50 0.012Antiviral activity against Influenza A virus WSN/1933 (H1N1) infected in human 293T cells after 20 hrs by luciferase reporter gene assay [AID760431, Type: Literature]
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2
[SID174494701]
EC50 0.023Antiviral activity against Measles virus Edmonston infected in african green monkey Vero cells after 20 hrs by luciferase reporter gene assay [AID760430, Type: Literature]
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3
[SID174494701]
EC50 0.05Antiviral activity against Influenza A virus A/Aichi/1968(H3N2) by firefly luciferase reporter gene assay [AID760433, Type: Literature]
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4
[SID174494701]
EC50 0.1Antiviral activity against Influenza A virus A/sw/Texas/2009(H1N1) virus by firefly luciferase reporter gene assay [AID760434, Type: Literature]
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5
[SID174494701]
EC50 0.14Antiviral activity against Respiratory syncytial virus by firefly luciferase reporter gene assay [AID760432, Type: Literature]
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6
[SID7973070]
Potency 0.2818qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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7
[SID104219274]
Potency 0.2818qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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8
[SID7973070]
Potency 0.2818qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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9
[SID7973070]
IC50 0.98A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 [AID588727, Type: confirmatory]
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10
[SID7973070]
Potency 4.4668High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment: PC3M Cytotoxicity [AID2733, Type: confirmatory]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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11
[SID7973070]
Potency 4.4668High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment: Confirmation of PNC Inhibition [AID2730, Type: confirmatory]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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12
[SID7973070]
IC50 4.57A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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13
[SID7973070]
CC50 6.25An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID2410, Type: confirmatory]
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14
[SID7973070]
Potency 10qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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15
[SID7973070]
Potency 25.1189qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) [AID1476, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
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16
[SID7973070]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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17
[SID7973070]
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators [AID639, Type: screening]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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18
[SID7973070]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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19
[SID7973070]
Non-Nucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity HTS Single Point (MLSMR Library) [AID841, Type: screening]
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20
[SID7973070]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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