isovaleric acid
(CID
10430
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Inactive(
1
)
Unspecified(3)
Top Targets:
MFS(
2
)
BioAssay Types:
Literature(
4
)
BioActivity Types:
Ki(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 5 Data Row: 5 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103701645
]
Active
Ki
32.3594
Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID
360149
, Type: Literature]
Solute carrier family 22 member 20 [gi:
56404586
]
View
X
Row No.
1
Structure
Substance
SID
103701645
CID
10430
Outcome
Active
Ki
32.3594 [uM]
BioAssay
Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr
AID
360149
BioAssay type
Literature
Target
Solute carrier family 22 member 20 [gi:
56404586
]
PubMed
17553798
Data Table
2
[SID
103701645
]
Unspecified
Ki
2344.23
Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID
360150
, Type: Literature]
Solute carrier family 22 member 6 [gi:
81901833
]
View
X
Row No.
2
Structure
Substance
SID
103701645
CID
10430
Outcome
Unspecified
Ki
2344.23 [uM]
BioAssay
Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr
AID
360150
BioAssay type
Literature
Target
Solute carrier family 22 member 6 [gi:
81901833
]
PubMed
17553798
Data Table
3
[SID
103701645
]
Unspecified
Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes [AID
360151
, Type: Literature]
View
X
Row No.
3
Structure
Substance
SID
103701645
CID
10430
Outcome
Unspecified
BioAssay
Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes
AID
360151
BioAssay type
Literature
Target
PubMed
17553798
Data Table
4
[SID
103701645
]
Unspecified
Inhibition of HDAC in human Hela cells nuclear extracts assessed as residual activity at 500 uM by fluorimetric assay [AID
447578
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
103701645
CID
10430
Outcome
Unspecified
BioAssay
Inhibition of HDAC in human Hela cells nuclear extracts assessed as residual activity at 500 uM by fluorimetric assay
AID
447578
BioAssay type
Literature
Target
PubMed
19520580
Data Table
5
[SID
57244195
]
Inactive
DSSTox (KIERBL) EPA Estrogen Receptor Ki Binding Study (Laws et al.) Database [AID
1576
, Type: other]
View
X
Row No.
5
Structure
Substance
SID
57244195
CID
10430
Outcome
Inactive
BioAssay
DSSTox (KIERBL) EPA Estrogen Receptor Ki Binding Study (Laws et al.) Database
AID
1576
BioAssay type
other
Target
PubMed
Data Table