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isovaleric acid (CID 10430) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(78)
 
 
Inconclusive(9)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
Summary(24)
 
 
 
Literature(4)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
Ki(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 91    Data Row: 91   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103701645]
Ki 32.3594Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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2
[SID103701645]
Ki 2344.23Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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3
[SID103701645]
Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes [AID360151, Type: Literature]
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4
[SID103701645]
Inhibition of HDAC in human Hela cells nuclear extracts assessed as residual activity at 500 uM by fluorimetric assay [AID447578, Type: Literature]
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5
[SID57244195]
DSSTox (KIERBL) EPA Estrogen Receptor Ki Binding Study (Laws et al.) Database [AID1576, Type: other]
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6
[SID144208802]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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7
[SID144208802]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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8
[SID144208802]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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9
[SID144208802]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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10
[SID144208802]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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11
[SID144208802]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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12
[SID144208802]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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13
[SID144208802]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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14
[SID144208802]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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15
[SID144208802]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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16
[SID144208802]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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17
[SID144208802]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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18
[SID144208802]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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19
[SID144208802]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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20
[SID144208802]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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