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NSC-747261 (CID 10411334) - Compound BioActivity Data
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BioActivity Outcomes:
Active(10)
 
 
Inactive(52)
 
 
Inconclusive(24)
 
 
Unspecified(59)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Literature(58)
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 145    Data Row: 145   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209847]
Potency-Replicate_1 2.7334qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID144209847]
AR Potency (uM) 3.18689qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144209847]
Potency-Replicate_1 3.861qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID144209847]
Potency-Replicate_1 4.3321qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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5
[SID144209847]
Potency-Replicate_1 6.1193qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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6
[SID144209847]
Ratio Potency (uM) 11.3075qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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7
[SID144209847]
Potency-Replicate_1 27.3338qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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8
[SID144209847]
Potency-Replicate_1 30.669qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144209847]
TR Potency (uM) 46.7771qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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10
[SID144209847]
Potency-Replicate_1 49.0321qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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11
[SID103718474]
Anticancer activity against human CCRF-CEM cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455379, Type: Literature]
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12
[SID103718474]
Anticancer activity against human HL-60(TB) cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455611, Type: Literature]
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13
[SID103718474]
Anticancer activity against human K562 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455612, Type: Literature]
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14
[SID103718474]
Anticancer activity against human MOLT4 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455613, Type: Literature]
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15
[SID103718474]
Anticancer activity against human RPMI8266 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455614, Type: Literature]
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16
[SID103718474]
Anticancer activity against human SR cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455615, Type: Literature]
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17
[SID103718474]
Anticancer activity against human A549 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455616, Type: Literature]
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18
[SID103718474]
Anticancer activity against human HOP62 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455618, Type: Literature]
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19
[SID103718474]
Anticancer activity against human HOP92 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455619, Type: Literature]
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20
[SID103718474]
Anticancer activity against human NCI-H226 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455620, Type: Literature]
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21
[SID103718474]
Anticancer activity against human NCI-H23 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455621, Type: Literature]
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22
[SID103718474]
Anticancer activity against human NCI-H322M cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455622, Type: Literature]
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23
[SID103718474]
Anticancer activity against human NCI-H460 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455623, Type: Literature]
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24
[SID103718474]
Anticancer activity against human NCI-H522 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455624, Type: Literature]
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25
[SID103718474]
Anticancer activity against human COLO205 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455625, Type: Literature]
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26
[SID103718474]
Anticancer activity against human HCC2998 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455626, Type: Literature]
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27
[SID103718474]
Anticancer activity against human HCT116 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455627, Type: Literature]
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28
[SID103718474]
Anticancer activity against human HCT15 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455628, Type: Literature]
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29
[SID103718474]
Anticancer activity against human HT-29 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455629, Type: Literature]
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30
[SID103718474]
Anticancer activity against human KM12 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455630, Type: Literature]
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31
[SID103718474]
Anticancer activity against human SW620 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455631, Type: Literature]
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32
[SID103718474]
Anticancer activity against human SF268 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455632, Type: Literature]
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33
[SID103718474]
Anticancer activity against human SF295 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455633, Type: Literature]
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34
[SID103718474]
Anticancer activity against human SF539 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455634, Type: other]
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35
[SID103718474]
Anticancer activity against human SNB19 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455635, Type: Literature]
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36
[SID103718474]
Anticancer activity against human SNB75 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455636, Type: Literature]
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37
[SID103718474]
Anticancer activity against human U251 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455637, Type: Literature]
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38
[SID103718474]
Anticancer activity against human LOXIMVI cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455638, Type: Literature]
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39
[SID103718474]
Anticancer activity against human MALME-3M cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455639, Type: Literature]
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40
[SID103718474]
Anticancer activity against human M14 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455640, Type: Literature]
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41
[SID103718474]
Anticancer activity against human SK-MEL-2 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455641, Type: Literature]
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42
[SID103718474]
Anticancer activity against human SK-MEL-28 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455642, Type: Literature]
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43
[SID103718474]
Anticancer activity against human SK-MEL-5 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455643, Type: Literature]
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44
[SID103718474]
Anticancer activity against human UACC257 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455644, Type: Literature]
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45
[SID103718474]
Anticancer activity against human UACC62 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455645, Type: Literature]
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46
[SID103718474]
Anticancer activity against human IGROV1 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455646, Type: Literature]
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47
[SID103718474]
Anticancer activity against human OVCAR-3 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455647, Type: Literature]
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48
[SID103718474]
Anticancer activity against human OVCAR4 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455648, Type: Literature]
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49
[SID103718474]
Anticancer activity against human OVCAR5 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455649, Type: Literature]
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50
[SID103718474]
Anticancer activity against human OVCAR8 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455650, Type: Literature]
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