Bookmark and Share
NSC-747261 (CID 10411334) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(11)
 
 
Inactive(53)
 
 
Inconclusive(22)
 
 
Unspecified(59)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Literature(59)
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 145    Data Row: 145   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209847]
Potency-Replicate_1 2.7334qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
2
[SID144209847]
AR Potency (uM) 3.18689qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
3
[SID144209847]
Potency-Replicate_1 3.861qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
4
[SID144209847]
Potency-Replicate_1 4.3321qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
5
[SID144209847]
Potency-Replicate_1 6.1193qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
6
[SID144209847]
Potency-Replicate_1 10.8818qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
7
[SID144209847]
Ratio Potency (uM) 11.3075qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
8
[SID144209847]
Potency-Replicate_1 27.3338qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
9
[SID144209847]
Potency-Replicate_1 30.669qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
10
[SID144209847]
TR Potency (uM) 46.7771qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
11
[SID144209847]
Potency-Replicate_1 49.0321qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
12
[SID103718474]
Anticancer activity against human CCRF-CEM cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455379, Type: Literature]
View
13
[SID103718474]
Anticancer activity against human HL-60(TB) cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455611, Type: Literature]
View
14
[SID103718474]
Anticancer activity against human K562 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455612, Type: Literature]
View
15
[SID103718474]
Anticancer activity against human MOLT4 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455613, Type: Literature]
View
16
[SID103718474]
Anticancer activity against human RPMI8266 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455614, Type: Literature]
View
17
[SID103718474]
Anticancer activity against human SR cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455615, Type: Literature]
View
18
[SID103718474]
Anticancer activity against human A549 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455616, Type: Literature]
View
19
[SID103718474]
Anticancer activity against human HOP62 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455618, Type: Literature]
View
20
[SID103718474]
Anticancer activity against human HOP92 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455619, Type: Literature]
View