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4-hydroxyphenylethanol (CID 10393) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(433)
 
 
Unspecified(24)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
ABCC CFTR1(4)
 
 
B zip1(4)
 
 
alkPPc(4)
 
 
BioAssay Types:
Screening(314)
 
 
Confirmatory(109)
 
 
 
Literature(39)
 
 
 
 
BioActivity Types:
Potency(97)
 
 
 
IC50(13)
 
 
 
Ki(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 434    Data Row: 468   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103242428]
Ki 0.85Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588183, Type: Literature]Beta-carbonic anhydrase 1 [gi:54042506]
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2
[SID103242428]
Ki 1.08Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588185, Type: Literature]
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3
[SID103242428]
Ki 1.1Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588184, Type: Literature]Carbonic anhydrase [gi:74656605]
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4
[SID103242428]
Ki 8.7Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay [AID588187, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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5
[SID103242428]
Ki 12.1Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588182, Type: Literature]PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) (Sulfate transporter/carbonic anhydrase, putative) [gi:81671928]
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6
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 5B by stopped flow CO2 hydration method [AID456400, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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7
[SID103242428]
Toxicity against Choristoneura fumiferana assessed as reduction in body weight by diet incorporation assay [AID361511, Type: Literature]
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8
[SID103242428]
Toxicity against Saccharomyces cerevisiae by disc diffusion method [AID361512, Type: Literature]
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9
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 5A by stopped flow CO2 hydration method [AID456399, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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10
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration method [AID456397, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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11
[SID103242428]
Antioxidant activity assessed as oxygen radical scavenging activity by ORAC assay [AID470188, Type: Literature]
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12
[SID103242428]
IC50 100Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay [AID740160, Type: Literature]
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13
[SID103242428]
IC50 100Antimigratory activity against human MDA-MB-231 cells after 24 hrs by wound healing assay [AID740168, Type: Literature]
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14
[SID103242428]
Ki 430Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay [AID588186, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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15
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method [AID456398, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID57260137]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID103242428]
Inhibition of c-MET phosphorylation (unknown origin) at 25 uM after 1 hr by Z'-LYTE kinase assay [AID740155, Type: Literature]Hepatocyte growth factor receptor [gi:251757497]
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18
[SID103242428]
Tested in vitro for cytotoxicity against He La cell line in human cervical carcinoma [AID88223, Type: other]
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19
[SID103242428]
Tested in vitro for cytotoxicity against MM96L cell line in human melanoma [AID106882, Type: other]
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20
[SID103242428]
Selectivity ratio of Kinact for human recombinant carbonic anhydrase 1 to Kinact for human recombinant carbonic anhydrase 5A [AID456401, Type: Literature]
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21
[SID103242428]
Selectivity ratio of Kinact for human recombinant carbonic anhydrase 2 to Kinact for human recombinant carbonic anhydrase 5A [AID456402, Type: Literature]
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22
[SID103242428]
Selectivity ratio of Kinact for human recombinant carbonic anhydrase 1 to Kinact for human recombinant carbonic anhydrase 5B [AID456403, Type: Literature]
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23
[SID103242428]
Selectivity ratio of Kinact for human recombinant carbonic anhydrase 2 to Kinact for human recombinant carbonic anhydrase 5B [AID456404, Type: Literature]
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24
[SID103242428]
Antioxidant activity assessed as DPPH radical scavenging activity at 300 uM after 48 hrs by spectrophotometry [AID470187, Type: Literature]
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25
[SID103242428]
Cytotoxicity against human MCF10A cells at IC50 in MDA-MB-231 MTT assay after 24 hrs by MTT assay [AID740158, Type: Literature]
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26
[SID103242428]
Cytotoxicity against human MCF10A cells at IC50 in wound healing assay after 24 hrs by MTT assay [AID740159, Type: Literature]
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27
[SID103242428]
Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay relative to phenol [AID588188, Type: Literature]Beta-carbonic anhydrase 1 [gi:54042506]
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28
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 1 to Ki for Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase [AID588190, Type: Literature]
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29
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 1 to Ki for Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase [AID588191, Type: Literature]
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30
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 1 to Ki for Candida albicans recombinant Nce103 beta-carbonic anhydrase [AID588192, Type: Literature]
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31
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 1 to Ki for Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase [AID588193, Type: Literature]
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32
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 2 to Ki for Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase [AID588194, Type: Literature]
View
33
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 2 to Ki for Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase [AID588195, Type: Literature]
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34
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 2 to Ki for Candida albicans recombinant Nce103 beta-carbonic anhydrase [AID588196, Type: Literature]
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35
[SID103242428]
Selectivity ratio of Ki for human recombinant alpha-carbonic anhydrase 2 to Ki for Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase [AID588197, Type: Literature]
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36
[SID57260137]
Potency 10qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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37
[SID57260137]
Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID624268, Type: screening]methionyl-tRNA synthetase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:71746704]
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38
[SID57260137]
Potency qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia [AID485349, Type: confirmatory]serine-protein kinase ATM [Homo sapiens] [gi:71902540]
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39
[SID57260138]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) [AID652126, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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40
[SID57260138]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12). [AID687014, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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41
[SID57260138]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite H. contortus (hcDAF-12) [AID652067, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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42
[SID57260137]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase [AID485367, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei] [gi:72386991]
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43
[SID57260137]
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA) [AID602163, Type: screening]MSRA protein [Bos taurus] [gi:73586699]
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44
[SID57260138]
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) [AID651718, Type: screening]MSRA protein [Bos taurus] [gi:73586699]
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45
[SID57260138]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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46
[SID57260137]
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1 [AID540275, Type: screening]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
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47
[SID57260137]
HTS Assay for Compounds that Act as Potentiators of the Vanilloid Receptor 1 [AID540277, Type: screening]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
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48
[SID57260137]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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49
[SID57260137]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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50
[SID57260137]
PgID: DNTB colorimetric HTS to detect inhibitor of PgID Measured in Biochemical System Using Plate Reader - 2164-01_Inhibitor_SinglePoint_HTS_Activity [AID602405, Type: screening]WlaI protein (PglD) [gi:75495260]
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