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4-hydroxyphenylethanol (CID 10393) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(441)
 
 
Unspecified(26)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
Troponin(4)
 
 
ANK(4)
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(315)
 
 
Confirmatory(110)
 
 
 
 
Literature(48)
 
 
 
 
BioActivity Types:
Potency(97)
 
 
 
IC50(15)
 
 
 
 
Ki(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 439    Data Row: 479   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103242428]
Ki 0.85Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588183, Type: Literature]Beta-carbonic anhydrase 1 [gi:614098993]
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2
[SID103242428]
Ki 1.08Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588185, Type: Literature]
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3
[SID103242428]
Ki 1.1Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588184, Type: Literature]Carbonic anhydrase [gi:74656605]
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4
[SID103242428]
IC50 7.5Inhibition of NADPH oxidase in Homo sapiens (human) HUVEC cells [AID1115334, Type: confirmatory]
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5
[SID103242428]
Ki 8.7Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay [AID588187, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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6
[SID103242428]
Ki 12.1Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID588182, Type: Literature]PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) (Sulfate transporter/carbonic anhydrase, putative) [gi:81671928]
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7
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 5B by stopped flow CO2 hydration method [AID456400, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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8
[SID103242428]
Toxicity against Choristoneura fumiferana assessed as reduction in body weight by diet incorporation assay [AID361511, Type: Literature]
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9
[SID103242428]
Toxicity against Saccharomyces cerevisiae by disc diffusion method [AID361512, Type: Literature]
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10
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 5A by stopped flow CO2 hydration method [AID456399, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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11
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration method [AID456397, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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12
[SID103242428]
Antioxidant activity assessed as oxygen radical scavenging activity by ORAC assay [AID470188, Type: Literature]
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13
[SID103242428]
IC50 100Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay [AID740160, Type: Literature]
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14
[SID103242428]
IC50 100Antimigratory activity against human MDA-MB-231 cells after 24 hrs by wound healing assay [AID740168, Type: Literature]
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15
[SID103242428]
Ki 430Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay [AID588186, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID103242428]
Antioxidant activity assessed as DPPH radical scavenging activity at 300 uM after 48 hrs by spectrophotometry [AID470187, Type: Literature]
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17
[SID103242428]
Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method [AID456398, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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18
[SID103242428]
Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated at 10 uM for 10 mins before substrate addition measured after 10 mins by HPLC analysis [AID1073064, Type: Literature]Arachidonate 5-lipoxygenase [gi:126407]
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19
[SID103242428]
Antifungal activity against Verticillium dahliae assessed as inhibition of mycelial radial growth measured after 350 hr [AID1090647, Type: Literature]
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20
[SID103242428]
Tested in vitro for cytotoxicity against He La cell line in human cervical carcinoma [AID88223, Type: other]
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