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BioActivity Data for Compound indan (CID 10326)

BioActivity Outcomes:
Inactive(17)
 
 
Unspecified(2)
 
 
Top Targets:
Esterase lipa..(1)
 
 
NR LBD RXR li..(1)
 
 
p450(1)
 
 
BioAssay Types:
Confirmatory(6)
 
 
Literature(5)
 
 
 
Summary(2)
 
 
BioAssay Categories:
In vitro(3)
 
 
Biochemical(3)
 
 
ADME(1)
 
 
Cell-based(3)
 
 
BioActivity Types:
Potency(8)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 19    Data Row: 19   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103464146]
IC50 550Inhibitory concentration against recombinant human cytochrome P450 1A2 [AID241334, Type: Literature]Cytochrome P450 1A2 [gi:117144]
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2
[SID103464146]
Octanol-water partition coefficient, log P of the compound [AID1145576, Type: Literature]
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3
[SID103464146]
Inhibition of human liver CE1 expressed in sf21 cells up to 100 uM [AID281483, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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4
[SID251919906]
Antagonist Potency (uM) qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway: Summary [AID1159523, Type: summary]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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5
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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6
[SID251919906]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the AP-1 signaling pathway: Summary [AID1159528, Type: summary]v-jun sarcoma virus 17 oncogene homolog (avian) [Homo sapiens] [gi:119627033]
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7
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the RXR signaling pathway [AID1159527, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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8
[SID103464146]
Inhibition of human intestinal carboxylesterase expressed in sf21 cells up to 100 uM [AID281482, Type: Literature]
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9
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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10
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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11
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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12
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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13
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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14
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway [AID1159526, Type: confirmatory]
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15
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the RXR signaling pathway - cell viability counter screen [AID1159529, Type: confirmatory]
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16
[SID71428]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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17
[SID103464146]
Inhibition of rabbit liver carboxylesterase expressed in sf21 cells up to 100 uM [AID281484, Type: Literature]
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18
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
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19
[SID251919906]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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