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BioActivity Data for Compound propionic acid (CID 1032)

BioActivity Outcomes:
Active(1)
 
 
Inactive(18)
 
 
Inconclusive(1)
 
 
Unspecified(25)
 
 
Top Targets:
MFS(3)
 
 
NR LBD RXR li..(2)
 
 
NT POLXc(2)
 
 
PolY Pol IV k..(2)
 
 
BioAssay Types:
Literature(36)
 
 
 
Confirmatory(6)
 
 
 
Summary(3)
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Biochemical(12)
 
 
 
Toxicity(4)
 
 
 
ADME(9)
 
 
Cell-based(13)
 
 
 
BioActivity Types:
Potency(9)
 
 
 
 
IC50(2)
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 45    Data Row: 45   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID251919690]
Ratio Potency (uM) 59.3239qHTS assay to identify small molecule agonists of the AP-1 signaling pathway: Summary [AID1159528, Type: summary]v-jun sarcoma virus 17 oncogene homolog (avian) [Homo sapiens] [gi:119627033]
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2
[SID103176199]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
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3
[SID103176199]
IC50 130Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production [AID454554, Type: Literature]Free fatty acid receptor 2 [gi:3122160]
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4
[SID103176199]
Ki 281.838Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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5
[SID103176199]
IC50 4000Inhibition of cell growth against human myeloid leukemia K562(S) cells [AID95143, Type: Literature]
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6
[SID103176199]
Ki 8128.31Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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7
[SID103176199]
Compound was evaluated for inhibitory activity against Candida albicans; 3.2-4 [AID45137, Type: Literature]
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8
[SID103176199]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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9
[SID103176199]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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10
[SID103176199]
Partition coefficient (logP) [AID23251, Type: Literature]
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11
[SID103176199]
Dissociation constant, pKa of the compound [AID342464, Type: Literature]
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12
[SID103176199]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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13
[SID103176199]
Compound was evaluated for erythroid induction of benzidine-positive K562 cells at concentration 4 mM after 9 day induction period [AID94968, Type: Literature]
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14
[SID103176199]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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15
[SID103176199]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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16
[SID103176199]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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17
[SID103176199]
Inhibition of HDAC in human Hela cells nuclear extracts assessed as residual activity at 500 uM by fluorimetric assay [AID447578, Type: Literature]
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18
[SID103176199]
Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes [AID360151, Type: Literature]
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19
[SID103176199]
Compound was evaluated for inhibitory activity against Saccharomyces cerevisiae; 3.2-4 [AID200327, Type: Literature]
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20
[SID103176199]
Toxicity in po dosed mouse [AID498775, Type: Literature]
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