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BioActivity Data for Compound Propylene Glycol (CID 1030)

BioActivity Outcomes:
Active(1)
 
 
Inactive(1161)
 
 
Inconclusive(22)
 
 
Unspecified(277)
 
 
Top Targets:
7tm 4(66)
 
 
 
NR LBD PPAR(36)
 
 
NR LBD ER(34)
 
 
 
 
NR LBD AR(33)
 
 
 
 
NR LBD GR(21)
 
 
 
BioAssay Types:
Confirmatory(810)
 
 
 
 
 
Screening(293)
 
 
Summary(96)
 
 
 
Literature(83)
 
 
 
BioAssay Categories:
In vitro(132)
 
 
In vivo(138)
 
 
 
Biochemical(228)
 
 
 
Toxicity(225)
 
 
 
 
 
ADME(1)
 
 
Cell-based(166)
 
 
 
Organism-base..(9)
 
 
BioActivity Types:
Potency(688)
 
 
 
 
 
IC50(124)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 915    Data Row: 1461   Total Pages: 74   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210326]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID103203075]
IC50 DRUGMATRIX: Glutamate, NMDA, Agonism radioligand binding (ligand: [3H] CGP-39653) [AID625266, Type: confirmatory]
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3
[SID103203075]
IC50 DRUGMATRIX: Calcium Channel Type L, Phenylalkylamine radioligand binding (ligand: [3H] (-)-Desmethoxyverapamil (D-888)) [AID625234, Type: confirmatory]
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4
[SID103203075]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: confirmatory]
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5
[SID103203075]
DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
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6
[SID103203075]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
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7
[SID103203075]
IC50 DRUGMATRIX: Potassium Channel [KATP] radioligand binding (ligand: [3H] Glyburide) [AID625170, Type: confirmatory]
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8
[SID103203075]
IC50 DRUGMATRIX: ATPase, Na+/K+ enzyme inhibition (substrate: ATP) [AID625210, Type: confirmatory]
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9
[SID103203075]
DRUGMATRIX: Atrial Natriuretic Factor (ANF) radioligand binding (ligand: [125I] ANF (rat)) [AID625211, Type: other]
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10
[SID103203075]
IC50 DRUGMATRIX: beta-Lactamase enzyme inhibition (substrate: Nitrocefin) [AID625212, Type: confirmatory]
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11
[SID103203075]
IC50 DRUGMATRIX: Calcium Channel Type L, Benzothiazepine radioligand binding (ligand: [3H] Diltiazem) [AID625215, Type: confirmatory]
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12
[SID103203075]
IC50 DRUGMATRIX: Calcium Channel Type L, Dihydropyridine radioligand binding (ligand: [3H] Nitrendipine) [AID625216, Type: confirmatory]
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13
[SID103203075]
IC50 DRUGMATRIX: Sigma2 radioligand binding (ligand: [3H] Ifenprodil) [AID625224, Type: confirmatory]
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14
[SID103203075]
IC50 DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: confirmatory]
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15
[SID103203075]
DRUGMATRIX: Tumor Necrosis Factor (TNF), Non-Selective radioligand binding (ligand: [125I] TNF-alpha) [AID625230, Type: other]
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16
[SID103203075]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: confirmatory]
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17
[SID103203075]
IC50 DRUGMATRIX: GABAA, Muscimol, Central radioligand binding (ligand: [3H] Muscimol) [AID625260, Type: confirmatory]
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18
[SID103203075]
IC50 DRUGMATRIX: GABAA, Flunitrazepam, Central radioligand binding (ligand: [3H] Flunitrazepam) [AID625261, Type: confirmatory]
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19
[SID103203075]
IC50 DRUGMATRIX: GABAA, Chloride Channel, TBOB radioligand binding (ligand: [3H] TBOB) [AID625262, Type: confirmatory]
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20
[SID103203075]
IC50 DRUGMATRIX: Glutamate, AMPA radioligand binding (ligand: [3H] AMPA) [AID625264, Type: confirmatory]
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