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Ninhydrin (CID 10236) - Compound BioActivity Data
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BioActivity Outcomes:
Active(50)
 
 
Inactive(280)
 
 
Inconclusive(198)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
P53(6)
 
 
 
 
BioAssay Types:
Confirmatory(245)
 
 
 
 
Screening(86)
 
 
 
Summary(24)
 
 
 
 
Literature(5)
 
 
 
BioActivity Types:
Potency(221)
 
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 355    Data Row: 533   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388857]
Potency 1.1906qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID144207903]
Potency-Replicate_1 11.0239qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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3
[SID144207903]
Potency-Replicate_1 19.4295qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144207903]
Potency-Replicate_1 24.4603qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID144207903]
Potency-Replicate_1 24.4603qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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6
[SID17388857]
Potency 25.1189qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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7
[SID144207903]
Potency-Replicate_1 27.4449qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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8
[SID144207903]
Potency-Replicate_1 27.4449qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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9
[SID17388857]
Potency 31.6228qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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10
[SID144207903]
Ratio Potency (uM) 31.9984qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144207903]
Ratio Potency (uM) 34.5511qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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12
[SID17388857]
Potency 37.578qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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13
[SID144207903]
Potency-Replicate_1 39.1143qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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14
[SID17388857]
Potency 50.1187Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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15
[SID17388857]
Potency 50.1187Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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16
[SID144207903]
Potency-Replicate_1 54.7598qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID144207903]
AhR Potency (uM) 54.7598qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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18
[SID144207903]
Potency-Replicate_1 61.4415qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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19
[SID17388857]
Potency 66.8242qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID85147162]
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5). [AID1987, Type: screening]PPP5C protein, partial [Homo sapiens] [gi:37589898]
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21
[SID85147162]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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22
[SID85147162]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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23
[SID85147162]
Fluorescence Polarization Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the LANA Histone H2A/H2B Interaction [AID2629, Type: screening]LANA [Human herpesvirus 8] [gi:139472804]
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24
[SID85147162]
HTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 8 (SENP8) [AID2540, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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25
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_11, Type: other]
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26
[SID17388857]
Cell Viability - N2a [AID540, Type: confirmatory]
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27
[SID17388857]
Cell Viability - Renal Proximal Tubule [AID545, Type: confirmatory]
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28
[SID17388857]
Cell Viability - Jurkat [AID426, Type: confirmatory]
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29
[SID17388857]
Cellular Toxicity (caspase-3) Jurkat [AID655, Type: confirmatory]
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30
[SID17388857]
Cell Viability - MRC5 [AID434, Type: confirmatory]
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31
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_24, Type: other]
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32
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_36, Type: other]
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33
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_61, Type: other]
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34
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_67, Type: other]
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35
[SID17388857]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_75, Type: other]
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36
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_75, Type: other]
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37
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_76, Type: other]
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38
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_73, Type: other]
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39
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_80, Type: other]
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40
[SID17388857]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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41
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_23, Type: other]
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42
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_14, Type: other]
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43
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_43, Type: other]
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44
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_53, Type: other]
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45
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_54, Type: other]
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46
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_58, Type: other]
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47
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_60, Type: other]
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48
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_61, Type: other]
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49
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_63, Type: other]
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50
[SID17388857]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_67, Type: other]
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