SureCN4463359 (CID 10193464) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(2)
 
 
Inconclusive(1)
 
 
Unspecified(455)
 
 
Top Targets:
PKc(48)
 
 
PKc like(40)
 
 
STKc AGC(28)
 
 
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
BioAssay Types:
Literature(3)
 
 
 
Confirmatory(3)
 
 
 
 
BioActivity Types:
Potency(3)
 
 
 
 
IC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 461    Data Row: 461   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103628926]
IC50 0.4Inhibition of CDK4 by radioactive glutathione plate-binding assay [AID348894, Type: Literature]
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2
[SID124350069]
Potency 4.6061qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
3
[SID103628926]
IC50 25Inhibition of GSK3-beta by scintillation proximity assay [AID348896, Type: Literature]
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4
[SID103628926]
 Dose normalized AUC in orally dosed mouse [AID348901, Type: Literature]
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5
[SID103628926]
 GSK_PKIS: PIP5K1 (Caliper assay) % inhibition at 5 uM [UNC Frye lab] [AID651545, Type: other]
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6
[SID103628926]
 GSK_PKIS: ABL1 (E255K mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651370, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
7
[SID103628926]
 GSK_PKIS: ABL1 (E255K mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651370, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
8
[SID103628926]
 GSK_PKIS: ABL1 (E255K mutant) mean inhibition at 1 uM [Nanosyn] [AID651371, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
9
[SID103628926]
 GSK_PKIS: ABL1 (E255K mutant) mean inhibition at 1 uM [Nanosyn] [AID651371, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID103628926]
 GSK_PKIS: ABL1 (H396P mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651372, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
11
[SID103628926]
 GSK_PKIS: ABL1 (H396P mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651372, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
12
[SID103628926]
 GSK_PKIS: ABL1 (H396P mutant) mean inhibition at 1 uM [Nanosyn] [AID651373, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
13
[SID103628926]
 GSK_PKIS: ABL1 (H396P mutant) mean inhibition at 1 uM [Nanosyn] [AID651373, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
14
[SID103628926]
 GSK_PKIS: ABL1 (M351T mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651374, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
15
[SID103628926]
 GSK_PKIS: ABL1 (M351T mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651374, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
16
[SID103628926]
 GSK_PKIS: ABL1 (M351T mutant) mean inhibition at 1 uM [Nanosyn] [AID651375, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
17
[SID103628926]
 GSK_PKIS: ABL1 (M351T mutant) mean inhibition at 1 uM [Nanosyn] [AID651375, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
18
[SID103628926]
 GSK_PKIS: ABL1 (Q252H mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651376, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID103628926]
 GSK_PKIS: ABL1 (Q252H mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651376, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
20
[SID103628926]
 GSK_PKIS: ABL1 (Q252H mutant) mean inhibition at 1 uM [Nanosyn] [AID651377, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
21
[SID103628926]
 GSK_PKIS: ABL1 (Q252H mutant) mean inhibition at 1 uM [Nanosyn] [AID651377, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
22
[SID103628926]
 GSK_PKIS: ABL1 (T315I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651378, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
23
[SID103628926]
 GSK_PKIS: ABL1 (T315I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651378, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
24
[SID103628926]
 GSK_PKIS: ABL1 (T315I mutant) mean inhibition at 1 uM [Nanosyn] [AID651379, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
25
[SID103628926]
 GSK_PKIS: ABL1 (T315I mutant) mean inhibition at 1 uM [Nanosyn] [AID651379, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
26
[SID103628926]
 GSK_PKIS: ABL1 (Y253F mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651380, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
27
[SID103628926]
 GSK_PKIS: ABL1 (Y253F mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651380, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
28
[SID103628926]
 GSK_PKIS: ABL1 (Y253F mutant) mean inhibition at 1 uM [Nanosyn] [AID651381, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
29
[SID103628926]
 GSK_PKIS: ABL1 (Y253F mutant) mean inhibition at 1 uM [Nanosyn] [AID651381, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
30
[SID103628926]
 GSK_PKIS: ABL1 mean inhibition at 0.1 uM [Nanosyn] [AID651382, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
31
[SID103628926]
 GSK_PKIS: ABL1 mean inhibition at 0.1 uM [Nanosyn] [AID651382, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
32
[SID103628926]
 GSK_PKIS: ABL1 mean inhibition at 1 uM [Nanosyn] [AID651383, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
33
[SID103628926]
 GSK_PKIS: ABL1 mean inhibition at 1 uM [Nanosyn] [AID651383, Type: other]Tyrosine-protein kinase ABL1 [gi:85681908]
View
34
[SID103628926]
 GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn] [AID651386, Type: other]Abelson tyrosine-protein kinase 2 [gi:1168268]
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35
[SID103628926]
 GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn] [AID651386, Type: other]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
36
[SID103628926]
 GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn] [AID651387, Type: other]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
37
[SID103628926]
 GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn] [AID651387, Type: other]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
38
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
39
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
40
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
41
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
42
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
43
[SID103628926]
 GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
44
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 0.1 uM [Nanosyn] [AID651020, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
45
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 0.1 uM [Nanosyn] [AID651020, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
46
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 0.1 uM [Nanosyn] [AID651020, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
47
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 1 uM [Nanosyn] [AID651021, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
48
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 1 uM [Nanosyn] [AID651021, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
49
[SID103628926]
 GSK_PKIS: AKT2 mean inhibition at 1 uM [Nanosyn] [AID651021, Type: other]RAC-beta serine/threonine-protein kinase [gi:1170703]
View
50
[SID103628926]
 GSK_PKIS: ALK mean inhibition at 0.1 uM [Nanosyn] [AID651384, Type: other]ALK tyrosine kinase receptor [gi:296439447]
View