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CHEMBL551148 (CID 10180742) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Unspecified(2)
 
 
Top Targets:
prostaglandin..(2)
 
 
 
BioAssay Types:
Literature(3)
 
 
 
BioActivity Types:
IC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103690694]
IC50 0.00028Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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2
[SID103690694]
IC50 100Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432546, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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3
[SID103690694]
Selectivity ratio of IC50 for human COX1 to IC50 for human COX2 expressed in african green monkey COS cells [AID432547, Type: Literature]
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