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CHEMBL468963 (CID 10173796) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(6)
 
 
Inconclusive(1)
 
 
Unspecified(458)
 
 
Top Targets:
PKc like(42)
 
 
PKc(42)
 
 
STKc AGC(16)
 
 
PTKc Abl(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Literature(6)
 
 
 
Confirmatory(6)
 
 
 
 
Screening(4)
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
IC50(3)
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 477    Data Row: 477   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103629016]
IC50 0.004Inhibition of human CDK2 by HTRF assay [AID348897, Type: Literature]Cyclin-dependent kinase 2 [gi:116051]
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2
[SID103629016]
IC50 0.006Inhibition of CDK4 by radioactive glutathione plate-binding assay [AID348894, Type: Literature]
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3
[SID103629016]
IC50 0.016Inhibition of GSK3-beta by scintillation proximity assay [AID348896, Type: Literature]
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4
[SID124349951]
Potency 0.3965qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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5
[SID124349951]
Potency 0.8227qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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6
[SID124349951]
Potency 3.1495qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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7
[SID124349951]
Potency 3.1495qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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8
[SID124349951]
Potency 3.6588qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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9
[SID85867796]
Inhibition of P. falciparum 3D7 [AID2306, Type: screening]L-lactate dehydrogenase [Plasmodium falciparum 3D7] [gi:124513266]
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10
[SID85867796]
Inhibition of HepG2 cell line [AID2303, Type: screening]
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11
[SID134352584]
A screen for small compounds that change glucocorticoid sensitivity in NFkB suppression [AID624486, Type: other]
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12
[SID85867796]
Inhibition of P. falciparum Dd2 [AID2302, Type: screening]lactate dehydrogenase [Plasmodium falciparum] [gi:111034851]
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13
[SID85867796]
XC50_3D7 1.07XC50 for P. falciparum 3D7 [AID2305, Type: confirmatory]
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14
[SID103629016]
AC50 3.6588GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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15
[SID103629016]
AC50 20.5749GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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16
[SID103629016]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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17
[SID103629016]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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18
[SID103629016]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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19
[SID103629016]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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20
[SID103629016]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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