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5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (CID 10138259) - Compound BioActivity Data
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BioActivity Outcomes:
Active(479)
 
 
Inactive(168)
 
 
Unspecified(298)
 
 
Top Targets:
PKc(109)
 
 
 
 
PKc like(81)
 
 
 
 
STKc AGC(44)
 
 
 
 
PTKc Abl(30)
 
 
 
 
PTKc EGFR(23)
 
 
 
 
BioAssay Types:
Literature(762)
 
 
 
Confirmatory(182)
 
 
 
BioActivity Types:
Kd(761)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 763    Data Row: 945   Total Pages: 48   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131277755]
Kd 0.00025Binding constant for KIT(V559D,V654A) kinase domain [AID435802, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
2
[SID131277755]
Kd 0.00025Binding constant for KIT(V559D,V654A) kinase domain [AID624793, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
3
[SID131277755]
Kd 0.00029Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
4
[SID131277755]
Kd 0.00029Binding constant for PDGFRB kinase domain [AID435926, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
5
[SID131277755]
Kd 0.00029Binding constant for PDGFRB kinase domain [AID624875, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
6
[SID131277755]
Kd 0.00051Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
7
[SID131277755]
Kd 0.00051Binding constant for KIT(V559D) kinase domain [AID435167, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
8
[SID131277755]
Kd 0.00054Binding constant for FLT3 kinase domain [AID435799, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
9
[SID131277755]
Kd 0.00054Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
10
[SID131277755]
Kd 0.00056Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
11
[SID131277755]
Kd 0.00056Binding constant for KIT(V559D,T670I) kinase domain [AID435675, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
12
[SID131277755]
Kd 0.00068Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
13
[SID131277755]
Kd 0.00068Binding constant for KIT kinase domain [AID435410, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
14
[SID131277755]
Kd 0.00068Binding affinity to human KIT incubated for 1 hr by kinase binding assay [AID599957, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
15
[SID131277755]
Kd 0.0007Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
16
[SID131277755]
Kd 0.0011Binding constant for PDGFRA kinase domain [AID625034, Type: Literature]Platelet-derived growth factor receptor alpha [gi:129892]
View
17
[SID131277755]
Kd 0.0011Binding constant for PDGFRA kinase domain [AID435827, Type: Literature]Platelet-derived growth factor receptor alpha [gi:129892]
View
18
[SID131277755]
Kd 0.0018Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
19
[SID131277755]
Kd 0.0018Binding constant for FLT3(ITD) kinase domain [AID435310, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
20
[SID131277755]
Kd 0.0023Binding constant for VEGFR2 kinase domain [AID624860, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
View