Bookmark and Share
CHEMBL298813 (CID 10076476) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(4)
 
 
Unspecified(1)
 
 
Top Targets:
PTKc Src(1)
 
 
BioAssay Types:
Confirmatory(4)
 
 
 
Literature(1)
 
 
BioActivity Types:
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103245513]
IC50 1.6Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domain [AID200411, Type: confirmatory]
View
2
[SID103245513]
IC50 4Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domain [AID157335, Type: confirmatory]
View
3
[SID103245513]
IC50 7.3Radioligand displacement assay for the binding of [125I]Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domain [AID201178, Type: confirmatory]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
4
[SID103245513]
Binding affinity towards SH2 domain of src protein tyrosine kinase(PTK) [AID201476, Type: Literature]
View
5
[SID103245513]
IC50 100Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domain [AID157337, Type: confirmatory]
View