Bookmark and Share
BioAssay: AID 92146

Tested for the inhibition of human Inducible nitric oxide synthase

Tested for the inhibition of human Inducible nitric oxide synthase ..more
_
   
 Tested Compounds
 Tested Compounds
All(1)
 
 
Active(1)
 
 
 Tested Substances
 Tested Substances
All(1)
 
 
Active(1)
 
 
 Related BioAssays
 Related BioAssays
AID: 92146
Data Source: ChEMBL (89336)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2014-05-12

Data Table ( Complete ):           Active    All
BioActive Compound: 1
Description:
Tested for the inhibition of human Inducible nitric oxide synthase
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 12425
Target Type: SINGLE PROTEIN
Pref Name: Nitric oxide synthase, inducible
Synonyms: HEP-NOS;Hepatocyte NOS;Inducible NO synthase;Inducible NOS;iNOS;Nitric oxide synthase; inducible;NOS type II;Peptidyl-cysteine S-nitrosylase NOS2;
Gene Name: NOS2;NOS2A;
Protein Accession: P35228;
Protein GI: 1352513;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: enzyme
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned


Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 13
First Page: 1763
Last Page: 1768
Categorized Comment
Assay Type: Binding

Assay Data Source: Scientific Literature

BAO: Assay Format: biochemical format

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Km*Km PubChem standard valueFloatμM
2Km activity commentKm activity commentString
3Km standard flagKm standard flagInteger
4Km qualifierKm qualifierString
5Km published valueKm published valueFloatμM
6Km standard valueKm standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
PageFrom: