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BioAssay: AID 91759

Tested in vitro for the inhibition constant against rat small intestinal isomaltase

Tested in vitro for the inhibition constant against rat small intestinal isomaltase ..more
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 Tested Compounds
 Tested Compounds
All(15)
 
 
Active(15)
 
 
 Tested Substances
 Tested Substances
All(15)
 
 
Active(15)
 
 
 Related BioAssays
 Related BioAssays
AID: 91759
Data Source: ChEMBL (88949)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2014-08-23

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 15
Description:
Tested in vitro for the inhibition constant against rat small intestinal isomaltase
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 12200
Target Type: SINGLE PROTEIN
Pref Name: Sucrase-isomaltase
Synonyms: Isomaltase;Sucrase;Sucrase-isomaltase; intestinal;
Gene Name: Si;
Protein Accession: P23739;
Protein GI: 1351132;
Organism: Rattus norvegicus
Tax ID: 10116
Target Classification: enzyme
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned


Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 3
First Page: 355
Last Page: 360
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Binding
Assay Data Source: Scientific Literature
Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Ki*Ki PubChem standard valueFloatμM
2Ki activity commentKi activity commentString
3Ki standard flagKi standard flagInteger
4Ki qualifierKi qualifierString
5Ki published valueKi published valueFloatμM
6Ki standard valueKi standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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