Bookmark and Share
BioAssay: AID 742992

Matrix metalloproteinase 7 inhibitor

This assay is created using drug mechanism and related information provided by ChEMBL. "INHIBITOR": Negatively effects (inhibits) the normal functioning of the protein e.g., prevention of enzymatic reaction or activation of downstream pathway. ..more
_
   
 Tested Compounds
 Tested Compounds
All(3)
 
 
Active(3)
 
 
 Tested Substances
 Tested Substances
All(3)
 
 
Active(3)
 
 
 Related BioAssays
 Related BioAssays
AID: 742992
Data Source: ChEMBL (drug_mech_966)
Depositor Category: Other
BioAssay Version:
Deposit Date: 2013-11-07
Modify Date: 2014-08-22

Data Table ( Complete ):           View Active Data    View All Data
Target
Sequence: RecName: Full=Matrilysin; AltName: Full=Matrin; AltName: Full=Matrix metalloproteinase-7; Short=MMP-7; AltName: Full=Pump-1 protease; AltName: Full=Uterine metalloproteinase; Flags: Precursor
Description ..   
Protein Family: ZnMc_MMP
Comment ..   

Gene:MMP7     Related Protein 3D Structures     More BioActivity Data..
BioActive Compounds: 3
Description:
This assay is created using drug mechanism and related information provided by ChEMBL. "INHIBITOR": Negatively effects (inhibits) the normal functioning of the protein e.g., prevention of enzymatic reaction or activation of downstream pathway.
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Target Type: Target is a single protein chain
Assay Data Source: Drug Mechanism
Drug Action Type: INHIBITOR
Result Definitions
Show more
TIDNameDescriptionAnnotationHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1MEC_IDDrug Mechanism IDInteger
2Action TypeType of action of the drug on the targetString
3Direct InteractionFlag to show whether the molecule is believed to interact directly with the targetString
4Molecular MechanismFlag to show whether the mechanism of action describes the molecular target of the drug, rather than a higher-level physiological mechanismString
5Disease EfficacyFlag to show whether the target assigned is believed to play a role in the efficacy of the drug in the indication(s) for which it is approvedString
6Mechanism CommentAdditional comments regarding the mechanism of actionString
7PubMed IDsPubMed IDs referred to the drug on the targetPMIDString
8Other RefsOther references referred to the drug on the targetString
9WHO NameWHO/INN name for the compoundString
10Level1 DescriptionDescription of first level of WHO ATC classificationString
11Level2 DescriptionDescription of second level of WHO ATC classificationString
12Level3 DescriptionDescription of third level of WHO ATC classificationString
13Level4 DescriptionDescription of fourth level of WHO ATC classificationString

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
Classification
PageFrom: