Bookmark and Share
BioAssay: AID 742643

Retinoid X receptor agonist

This assay is created using drug mechanism and related information provided by ChEMBL. "AGONIST": Binds to and activates a receptor, often mimicking the effect of the endogenous ligand. ..more
_
   
 Tested Compounds
 Tested Compounds
All(1)
 
 
Active(1)
 
 
 Tested Substances
 Tested Substances
All(1)
 
 
Active(1)
 
 
 Related BioAssays
 Related BioAssays
AID: 742643
Data Source: ChEMBL (drug_mech_1576)
Depositor Category: Other
BioAssay Version:
Deposit Date: 2013-11-07
Modify Date: 2014-05-05

Data Table ( Complete ):           Active    All
Targets
Sequence: RecName: Full=Retinoic acid receptor RXR-alpha; AltName: Full=Nuclear receptor subfamily 2 group B member 1; AltName: Full=Retinoid X receptor alpha
Description ..   
Protein Family: The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
Comment ..   

Gene:RXRA     Related Protein 3D Structures     More BioActivity Data..


more...  
BioActive Compound: 1
Description:
This assay is created using drug mechanism and related information provided by ChEMBL. "AGONIST": Binds to and activates a receptor, often mimicking the effect of the endogenous ligand.
Categorized Comment
Drug Action Type: AGONIST

Assay Data Source: Drug Mechanism

Target Type: Target is a group of closely related proteins

Result Definitions
Show more
TIDNameDescriptionAnnotationHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1MEC_IDDrug Mechanism IDInteger
2Action TypeType of action of the drug on the targetString
3Direct InteractionFlag to show whether the molecule is believed to interact directly with the targetString
4Molecular MechanismFlag to show whether the mechanism of action describes the molecular target of the drug, rather than a higher-level physiological mechanismString
5Disease EfficacyFlag to show whether the target assigned is believed to play a role in the efficacy of the drug in the indication(s) for which it is approvedString
6PubMed IDsPubMed IDs referred to the drug on the targetPMIDString
7Other RefsOther references referred to the drug on the targetString
8WHO NameWHO/INN name for the compoundString
9Level1 DescriptionDescription of first level of WHO ATC classificationString
10Level2 DescriptionDescription of second level of WHO ATC classificationString
11Level3 DescriptionDescription of third level of WHO ATC classificationString
12Level4 DescriptionDescription of fourth level of WHO ATC classificationString

Data Table (Concise)
Classification
PageFrom: