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BioAssay: AID 73760

In vitro inhibition constant against rat small intestinal glucoamylase

In vitro inhibition constant against rat small intestinal glucoamylase ..more
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 Tested Compounds
 Tested Compounds
All(13)
 
 
Active(13)
 
 
 Tested Substances
 Tested Substances
All(13)
 
 
Active(13)
 
 
 Related BioAssays
 Related BioAssays
AID: 73760
Data Source: ChEMBL (70932)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2014-05-12

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 13
Description:
In vitro inhibition constant against rat small intestinal glucoamylase
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 1
Target Type: SINGLE PROTEIN
Pref Name: Maltase-glucoamylase
Synonyms: Alpha-glucosidase;Glucan 1;4-alpha-glucosidase;Glucoamylase;Maltase;Maltase-glucoamylase; intestinal;
Gene Name: MGA ;MGAM;MGAML;
Protein Accession: O43451;
Protein GI: 215274260;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: enzyme hydrolase
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned


Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 3
First Page: 355
Last Page: 360
Categorized Comment
Assay Type: Binding

Assay Data Source: Scientific Literature

BAO: Assay Format: biochemical format

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Ki*Ki PubChem standard valueFloatμM
2Ki activity commentKi activity commentString
3Ki standard flagKi standard flagInteger
4Ki qualifierKi qualifierString
5Ki published valueKi published valueFloatμM
6Ki standard valueKi standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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