Displacement of [125I]MCP1 from CCR2 in human PBMC at 1 uM after 30 mins by gamma counter - BioAssay Summary
Displacement of [125I]MCP1 from CCR2 in human PBMC at 1 uM after 30 mins by gamma counter ..more
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 Tested Compounds
 Tested Compounds
All(12)
 
 
Unspecified(12)
 
 
 Tested Substances
 Tested Substances
All(12)
 
 
Unspecified(12)
 
 
 Related BioAssays
 Related BioAssays
Table of Contents
AID: 645526
Data Source: ChEMBL (802974)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2012-09-09
Modify Date: 2013-05-16

Data Table (Complete):           All
Target
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Sequence: RecName: Full=C-C chemokine receptor type 2; Short=C-C CKR-2; Short=CC-CKR-2; Short=CCR-2; Short=CCR2; AltName: Full=Monocyte chemoattractant protein 1 receptor; Short=MCP-1-R; AltName: CD_antigen=CD192
Description ..   
Comment ..   

Gene:CCR2     Conserved Domain     Related Protein 3D Structures
Tested Compounds:
Description:
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Displacement of [125I]MCP1 from CCR2 in human PBMC at 1 uM after 30 mins by gamma counter
Comment
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Publication:
Journal: ACS Med. Chem. Lett.
Year: 2011
Volume: 2
Issue: 6
First Page: 450
Last Page: 454
Categorized Comment
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ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature

ChEMBL Target ID: 11575

ChEMBL target type: Target is a single protein chain

Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Inhibition activity commentInhibition activity commentString
2Inhibition standard flagInhibition standard flagInteger
3Inhibition qualifierInhibition qualifierString
4Inhibition published valueInhibition published valueFloat%
5Inhibition standard valueInhibition standard valueFloat%

Data Table (Concise)
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Classification
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