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BioAssay: AID 625176

DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA)

DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) ..more
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 Tested Compounds
 Tested Compounds
All(843)
 
 
Unspecified(843)
 
 
 Tested Substances
 Tested Substances
All(909)
 
 
Unspecified(909)
 
 
 Related BioAssays
 Related BioAssays
AID: 625176
Data Source: ChEMBL (774674)
Depositor Category: Other
BioAssay Version:
Deposit Date: 2012-09-09
Modify Date: 2014-05-26

Data Table ( Complete ):           View All Data
Target
Sequence: RecName: Full=Neutrophil elastase; AltName: Full=Bone marrow serine protease; AltName: Full=Elastase-2; AltName: Full=Human leukocyte elastase; Short=HLE; AltName: Full=Medullasin; AltName: Full=PMN elastase; Flags: Precursor
Description ..   
Protein Family: Tryp_SPc
Comment ..   

Gene:ELANE     Related Protein 3D Structures     More BioActivity Data..
Tested Compounds:
Description:
DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA)
Categorized Comment
Assay Type: Binding

Assay Data Source: DrugMatrix in vitro pharmacology assays

Assay Test Type: In vitro

BAO: Assay Format: biochemical format

Assay Tissue: Neutrophils

Target Type: Target is a single protein chain

Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1IC50 activity commentIC50 activity commentString
2IC50 standard flagIC50 standard flagInteger
3IC50 qualifierIC50 qualifierString
4IC50 published valueIC50 published valueFloat
5IC50 standard valueIC50 standard valueFloat
6Ki activity commentKi activity commentString
7Ki standard flagKi standard flagInteger
8Ki qualifierKi qualifierString
9Ki published valueKi published valueFloat
10Ki standard valueKi standard valueFloat

Data Table (Concise)
Data Table ( Complete ):     View All Data
Classification
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