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BioAssay: AID 625158

DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine)

DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) ..more
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 Tested Compounds
 Tested Compounds
All(841)
 
 
Active(2)
 
 
Unspecified(839)
 
 
 Tested Substances
 Tested Substances
All(898)
 
 
Active(2)
 
 
Unspecified(896)
 
 
 Related BioAssays
 Related BioAssays
AID: 625158
Data Source: ChEMBL (774656)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Other
BioAssay Version:
Deposit Date: 2012-09-09
Modify Date: 2014-08-25

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 2
Description:
DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine)
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 22226
Target Type: UNCHECKED
Pref Name: Unchecked
Confidence: Default value - Target unknown or has yet to be assigned
Relationship Type: Default value - Target has yet to be curated
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Binding
Assay Data Source: DrugMatrix
Assay Cell Type: IMR-32
Assay Test Type: In vitro
Assay Subcellular Fraction: membranes
Result Definitions
Show more
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1IC50*IC50 PubChem standard valueFloatμM
2IC50 activity commentIC50 activity commentString
3IC50 standard flagIC50 standard flagInteger
4IC50 qualifierIC50 qualifierString
5IC50 published valueIC50 published valueFloatμM
6IC50 standard valueIC50 standard valueFloatnM
7Ki activity commentKi activity commentString
8Ki standard flagKi standard flagInteger
9Ki qualifierKi qualifierString
10Ki published valueKi published valueFloatμM
11Ki standard valueKi standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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