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BioAssay: AID 600466

Agonist activity at PPARalpha relative to fenofibric acid

Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
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 Tested Compounds
 Tested Compounds
All(3)
 
 
Unspecified(3)
 
 
 Tested Substances
 Tested Substances
All(3)
 
 
Unspecified(3)
 
 
 Related BioAssays
 Related BioAssays
AID: 600466
Data Source: ChEMBL (750617)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2012-02-15
Modify Date: 2014-05-25

Data Table ( Complete ):           View All Data
Tested Compounds:
Description:
Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
(PMID: 21344906)
Comment
Putative Target:

ChEMBL Target ID: 163
Target Type: SINGLE PROTEIN
Pref Name: Peroxisome proliferator-activated receptor alpha
Synonyms: Nuclear receptor subfamily 1 group C member 1;Peroxisome proliferator-activated receptor alpha;PPAR-alpha;
Gene Name: NR1C1 ;PPAR;PPARA;
Protein Accession: Q07869;
Protein GI: 3041727;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: transcription factor nuclear receptor nr1 nr1c nr1c1
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
Categorized Comment - additional comments and annotations
From ChEMBL:
Assay Type: Functional
Assay Data Source: Scientific Literature
Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Efficacy activity commentEfficacy activity commentString
2Efficacy standard flagEfficacy standard flagInteger
3Efficacy qualifierEfficacy qualifierString
4Efficacy published valueEfficacy published valueFloat%
5Efficacy standard valueEfficacy standard valueFloat%

Data Table (Concise)
Data Table ( Complete ):     View All Data
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