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BioAssay: AID 600465

Agonist activity at PPARgamma at 1 uM

Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
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 Tested Compounds
 Tested Compounds
All(8)
 
 
Inactive(8)
 
 
 Tested Substances
 Tested Substances
All(8)
 
 
Inactive(8)
 
 
 Related BioAssays
 Related BioAssays
AID: 600465
Data Source: ChEMBL (750616)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2012-02-15
Modify Date: 2013-11-17

Data Table ( Complete ):           All
Tested Compounds:
Description:
Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
(PMID: 21344906)
Comment
Putative Target:

ChEMBL Target ID: 133
Target Type: SINGLE PROTEIN
Pref Name: Peroxisome proliferator-activated receptor gamma
Synonyms: Nuclear receptor subfamily 1 group C member 3;Peroxisome proliferator-activated receptor gamma;PPAR-gamma;
Gene Name: NR1C3;PPARG;
Protein Accession: P37231;
Protein GI: 13432234;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: transcription factor nuclear receptor nr1 nr1c nr1c3
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
Categorized Comment
ChEMBL Assay Type: Functional

ChEMBL Assay Data Source: Scientific Literature

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Activity activity commentActivity activity commentString
2Activity standard flagActivity standard flagInteger
3Activity qualifierActivity qualifierString
4Activity published valueActivity published valueFloat
5Activity standard valueActivity standard valueFloat

Data Table (Concise)
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