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BioAssay: AID 600464

Displacement of [3H]-MDL 105519 from NMDA receptor in rat brain membranes

Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
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 Tested Compounds
 Tested Compounds
All(2)
 
 
Active(2)
 
 
 Tested Substances
 Tested Substances
All(2)
 
 
Active(2)
 
 
 Related BioAssays
 Related BioAssays
AID: 600464
Data Source: ChEMBL (750615)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2012-02-15
Modify Date: 2013-05-15

Data Table ( Complete ):           Active    All
BioActive Compounds: 2
Description:
Title: Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
(PMID: 21344906)
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 22226
Target Type: UNCHECKED
Pref Name: Unchecked
Confidence: Default value - Target unknown or has yet to be assigned
Relationship Type: Default value - Target has yet to be curated
Categorized Comment
ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Ki*Ki PubChem standard valueFloatμM
2Ki activity commentKi activity commentString
3Ki standard flagKi standard flagInteger
4Ki qualifierKi qualifierString
5Ki published valueKi published valueFloatnM
6Ki standard valueKi standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
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