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BioAssay: AID 553585

Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity at 10 uM by CRE-driven luciferase reporter gene assay relative to control

Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity at 10 uM by CRE-driven luciferase reporter gene assay relative to control ..more
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 Tested Compounds
 Tested Compounds
All(5)
 
 
Unspecified(5)
 
 
 Tested Substances
 Tested Substances
All(5)
 
 
Unspecified(5)
 
 
 Related BioAssays
 Related BioAssays
AID: 553585
Data Source: ChEMBL (702113)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2011-09-18
Modify Date: 2014-05-26

Data Table ( Complete ):           View All Data
Target
Sequence: RecName: Full=Follicle-stimulating hormone receptor; Short=FSH-R; AltName: Full=Follitropin receptor; Flags: Precursor
Description ..   
Protein Family: Gonadotropin hormone receptor transmembrane region
Comment ..   

Gene:FSHR     Related Protein 3D Structures     More BioActivity Data..
Tested Compounds:
Description:
Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity at 10 uM by CRE-driven luciferase reporter gene assay relative to control
Comment


Publication:
Journal: ACS Med. Chem. Lett.
Year: 2011
Volume: 2
Issue: 1
First Page: 85
Last Page: 89
Categorized Comment
Assay Type: Functional

Assay Data Source: Scientific Literature

BAO: Assay Format: cell-based format

Assay Cell Type: CHO-K1

Target Type: Target is a single protein chain

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Emax activity commentEmax activity commentString
2Emax standard flagEmax standard flagInteger
3Emax qualifierEmax qualifierString
4Emax published valueEmax published valueFloat%
5Emax standard valueEmax standard valueFloat%

Data Table (Concise)
Data Table ( Complete ):     View All Data
Classification
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