Antagonist activity at human LH receptor expressed in CHO-K1 cells assessed as inhibition of LH-induced luciferase activity by CRE-driven luciferase reporter gene assay - BioAssay Summary
Antagonist activity at human LH receptor expressed in CHO-K1 cells assessed as inhibition of LH-induced luciferase activity by CRE-driven luciferase reporter gene assay ..more
 _
   
 Tested Compounds
 Tested Compounds
All(14)
 
 
Inactive(14)
 
 
 Tested Substances
 Tested Substances
All(14)
 
 
Inactive(14)
 
 
 Related BioAssays
 Related BioAssays
Table of Contents
AID: 553582
Data Source: ChEMBL (702110)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2011-09-18
Modify Date: 2013-05-13

Data Table (Complete):           All
Target
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Sequence: RecName: Full=Lutropin-choriogonadotropic hormone receptor; Short=LH/CG-R; AltName: Full=Luteinizing hormone receptor; Short=LHR; Short=LSH-R; Flags: Precursor
Description ..   
Comment ..   

Gene:LHCGR     Conserved Domain     Related Protein 3D Structures
Tested Compounds:
Description:
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Antagonist activity at human LH receptor expressed in CHO-K1 cells assessed as inhibition of LH-induced luciferase activity by CRE-driven luciferase reporter gene assay
Comment
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Publication:
Journal: ACS Med. Chem. Lett.
Year: 2011
Volume: 2
Issue: 1
First Page: 85
Last Page: 89
Categorized Comment
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ChEMBL Assay Type: Functional

ChEMBL Assay Data Source: Scientific Literature

ChEMBL Target ID: 95

ChEMBL target type: Target is a single protein chain

Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Inhibition activity commentInhibition activity commentString
2Inhibition standard flagInhibition standard flagInteger
3Inhibition qualifierInhibition qualifierString
4Inhibition published valueInhibition published valueFloat
5Inhibition standard valueInhibition standard valueFloat

Data Table (Concise)
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