Binding affinity to human Hsc70 by isothermal calorimetry assay - BioAssay Summary
Title: ATPases as drug targets: insights from heat shock proteins 70 and 90.
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 Tested Compounds
 Tested Compounds
All(1)
 
 
Active(1)
 
 
 Tested Substances
 Tested Substances
All(1)
 
 
Active(1)
 
 
 Related BioAssays
 Related BioAssays
Table of Contents
AID: 527455
Data Source: ChEMBL (675336)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2011-09-18
Modify Date: 2013-05-13

Data Table (Complete):           Active    All
BioActive Compound: 1
Description:
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Title: ATPases as drug targets: insights from heat shock proteins 70 and 90.
(PMID: 20608738)
Comment
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Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 103588
Target Type: SINGLE PROTEIN
Pref Name: Heat shock cognate 71 kDa protein
Description: Heat shock cognate 71 kDa protein
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a single protein chain
Categorized Comment
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ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature

Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Kd*Kd PubChem standard valueFloatμM
2BEIBinding Efficiency Index(nM)Float
3SEISurface Efficiency Index(nM)Float
4Kd activity commentKd activity commentString
5Kd standard flagKd standard flagInteger
6Kd qualifierKd qualifierString
7Kd published valueKd published valueFloatnM
8Kd standard valueKd standard valueFloatnM
* Activity Concentration.

Data Table (Concise)
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