Title: ATPases as drug targets: insights from heat shock proteins 70 and 90.
(PMID: 20608738)

Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: Cyclin-dependent kinase 2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: Cyclin-dependent kinase 2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: Cyclin-dependent kinase 2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E1
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E1
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E1
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Target ID: 104708
Target Type: PROTEIN COMPLEX
Pref Name: Cyclin-dependent kinase 2/cyclin E
Description: G1/S-specific cyclin-E2
Organism: Homo sapiens
Tax ID: 9606
Confidence: Homologous protein complex subunits assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a defined protein complex, consisting of multiple subunits

ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature