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BioAssay: AID 504473

Flow cytometric HTS Screen of Saccharomyces cerevisiae GFP-tagged clones sensitive to rapamycin

Assay Implementation: Jun Chen, Stephanie Chavez, Terry Foutz, Cristian Bologa, Oleg Ursu, Mark Carter ..more
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 Tested Compounds
 Tested Compounds
All(5)
 
 
Active(5)
 
 
Inactive(5)
 
 
 Tested Substances
 Tested Substances
All(5)
 
 
Active(5)
 
 
Inactive(5)
 
 
 Related BioAssays
 Related BioAssays
AID: 504473
Data Source: NMMLSC (UNMCMD_TOR_SECONDARY_RAPAMYCIN_GFPCOLLECTION_SET1)
BioAssay Type: Panel
Depositor Category: NIH Molecular Libraries Probe Production Network
Deposit Date: 2011-03-17
Hold-until Date: 2012-03-12
Modify Date: 2012-03-12

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 5
Related Experiments
Show more
AIDNameTypeProbeComment
1908Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiaeSummary1 depositor-specified cross reference: Summary Report for Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisia
1862Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_RPL19AScreening same project related to Summary assay
1867Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_MEP2Screening same project related to Summary assay
1870Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_CIT2Screening same project related to Summary assay
1873Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_LAP4Screening same project related to Summary assay
1887Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_AGP1Screening same project related to Summary assay
2016Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ MEP2_MLPCN.Screening same project related to Summary assay
2023Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN.Screening same project related to Summary assay
2025Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ RPL19A_MLPCN.Screening same project related to Summary assay
2029Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ CIT2_MLPCN.Screening same project related to Summary assay
2066Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ AGP1_MLPCN.Screening same project related to Summary assay
2270Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically RPL19A Cherry Pick CompoundsScreening same project related to Summary assay
2271Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically LAP4 Cherry Pick CompoundsScreening same project related to Summary assay
2272Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically MEP2 Cherry Pick CompoundsScreening same project related to Summary assay
2273Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically AGP1 Cherry Pick CompoundsScreening same project related to Summary assay
2274Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically CIT2 Cherry Pick CompoundsScreening same project related to Summary assay
2621Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 Second Cherry Pick CompoundsScreening same project related to Summary assay
2622Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 Second Cherry Pick CompoundsScreening same project related to Summary assay
2623Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A Second Cherry Pick CompoundsScreening same project related to Summary assay
2624Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically CIT2 Second Cherry Pick CompoundsScreening same project related to Summary assay
2643Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 Second Cherry Pick CompoundsScreening same project related to Summary assay
2740Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hitsConfirmatory same project related to Summary assay
2742Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hitsConfirmatory same project related to Summary assay
2743Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hitsConfirmatory same project related to Summary assay
2744Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically CIT2 based on MLPCN hitsConfirmatory same project related to Summary assay
2745Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hitsConfirmatory same project related to Summary assay
2757Test compound autofluorescence in Saccharomyes cerevisiae specifically s288cOther same project related to Summary assay
488790Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1Confirmatory same project related to Summary assay
488792Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1Confirmatory same project related to Summary assay
488795Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4Confirmatory same project related to Summary assay
488801Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2Confirmatory same project related to Summary assay
488808Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19AConfirmatory same project related to Summary assay
488812Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2Confirmatory same project related to Summary assay
488814Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19AConfirmatory same project related to Summary assay
488818Phenotypic Counterscreen Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically s288cOther same project related to Summary assay
488823Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4Confirmatory same project related to Summary assay
488825Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically CIT2Confirmatory same project related to Summary assay
488827Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically CIT2Confirmatory same project related to Summary assay
488829Phenotypic Counterscreen Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically s288cOther same project related to Summary assay
504321Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 Third Cherry Pick CompoundsScreening same project related to Summary assay
504334Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 Third Cherry Pick CompoundsScreening same project related to Summary assay
504336Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A Third Cherry Pick CompoundsScreening same project related to Summary assay
504338Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 Third Cherry Pick CompoundsScreening same project related to Summary assay
504340Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically CIT2 Third Cherry Pick CompoundsScreening same project related to Summary assay
504456Yeast TORC1 Bypass Cell Growth AssayOther same project related to Summary assay
504458Confirmatory Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1Confirmatory same project related to Summary assay
504461Confirmatory Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically CIT2Confirmatory same project related to Summary assay
504463Phenotypic Counterscreen Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically s288cOther same project related to Summary assay
504468Confirmatory Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2Confirmatory same project related to Summary assay
504469Confirmatory Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4Confirmatory same project related to Summary assay
504470Confirmatory Primary Screen Hits KU SAR Set2 Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19AConfirmatory same project related to Summary assay
504471Rtg3-GFP translocation assayOther same project related to Summary assay
504472Gln3p-GFP Translocation AssayOther same project related to Summary assay
504478Sch9 phosphorylation assay (AP)Other same project related to Summary assay
504479Expression of GFP-tagged protein in TOR C1 bypass strains and wild type Saccharomyces cerevisiaeOther same project related to Summary assay
504481Expression of GFP-tagged protein in Transducer mutant strains of Saccharomyces cerevisiaeOther same project related to Summary assay
Description:
University of New Mexico Assay Overview:
Assay Support: 1R03 MH086450-01
Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. cerevisiae
Assay Provider: Maggie Werner-Washburne
UNMScreening Center/ PI: UNMCMD/ Larry Sklar
Lead Biologist: Jun Chen PhD
Chemistry Center/ PI: University of Kansas Specialized Chemistry Center/ Jeff Aube
Chemistry Center Lead: Jennifer Golden, Blake Peterson
Assay Implementation: Jun Chen, Stephanie Chavez, Terry Foutz, Cristian Bologa, Oleg Ursu, Mark Carter
Screening Operations Team: Mark Carter, J. Jacob Strouse, Anna Waller, Virginia Salas

Assay Background and Significance:

The target of rapamycin, TOR, is a ser/thr protein kinase evolutionary conserved from yeast to man [Wullschleger, et al, 2006]. TOR functions in two distinct protein complexes, TOR complex 1 (TORC1) and TORC2 [Cafferkey, et al. 1993; Stan, et al. 1994]. Curiously, only TOR in TORC1 is bound and inhibited by the lipophilic macrolide rapamycin [Kunz, et al. 1993; Helliwell, et al. 1998; Zhang, et al. 2006]. Although the signaling events up- and downstream of TORC2 (which regulates spatial aspects of growth) have yet to be elucidated in detail, it is well established that TORC1 is a central hub of a signaling network that couples cues from hormones and growth factors (in mammalian cells), energy and stresses, and the abundance of nutrients, to cell growth and proliferation. Very recent work has elucidated many details of the signaling events upstream of TORC1 as well as downstream targets of TORC1. Importantly, in this context, most negative regulators of mammalian TORC1 (mTORC1)have been previously identified as tumor suppressor gene products, while many positive regulators of mTORC1 have been identified as proto-oncoproteins and/or are found at elevated levels in tumor-derived cell lines [De Virgilio, et al. 2006a; De Virgilio, et al. 2006b].
Panel Information
Panel of Rapamycin sensative GFP-tagged S. cerevisiae strains - Panel of Rapamycin sensative GFP-tagged S. cerevisiae strains
    Data Table(Active)    Data Table(All)Show more
PID§NameSubstancePanel TargetsDescriptionAdditional Information
ActiveInactive
1YMR120C41 [Gene ID:855149]
ADE17 Ade17p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
2YCL025C23 [Gene ID:850333]
AGP1 Agp1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
3YLR109W14 [Gene ID:850799]
AHP1 Ahp1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
4YHR018C23 [Gene ID:856411]
ARG4 Arg4p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
5YPR145W23 [Gene ID:856268]
ASN1 Asn1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
6YJR148W32 [Gene ID:853613]
BAT2 Bat2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
7YAL060W32 [Gene ID:851239]
BDH1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
8YEL063C14 [Gene ID:856646]
CAN1 Can1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
9YPL111W23 [Gene ID:855993]
CAR1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
10YIL043C5 [Gene ID:854768]
CBR1 Cbr1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
11YCR002C14 [Gene ID:850358]
CDC10 Cdc10p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
12YCL064C5 [Gene ID:850295]
CHA1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
13YNR001C23 [Gene ID:855732]
CIT1 Cit1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
14YCR005C32 [Gene ID:850361]
CIT2 Cit2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
15YGR088W23 [Gene ID:852979]
CTT1 Ctt1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
16YNL112W5 [Gene ID:855611]
DBP2 Dbp2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
17YHR144C5 [Gene ID:856548]
DCD1 Dcd1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
18YOR173W14 [Gene ID:854344]
DCS2 Dcs2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
19YOL052C-A32 [Gene ID:854104]
DDR2 Ddr2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
20YPL265W41 [Gene ID:855863]
DIP5 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
21YEL071W41 [Gene ID:856638]
DLD3 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
22YBR208C23 [Gene ID:852507]
DUR1_2 Dur1_2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
23YNL068C5 [Gene ID:855656]
FKH2 Fkh2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
24YHL021C23 [Gene ID:856365]
AIM17 Aim17p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
25YDR070C32 [Gene ID:851642]
FMP16 Fmp16p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
26YKR039W23 [Gene ID:853912]
GAP1 Gap1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
27YMR307W5 [Gene ID:855355]
GAS1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
28YPR184W23 [Gene ID:856314]
GDB1#Gdb1p [#Saccharomyces cerevisiae S288c#]Taxonomy id: 559292
29YOR375C23 [Gene ID:854557]
GDH1 Gdh1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
30YML004C5 [Gene ID:855009]
GLO1 Glo1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
31YOR371C5 [Gene ID:854553]
GPB1 Gpb1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
32YDL205C5 [Gene ID:851322]
HEM3 Hem3p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
33YOR038C5 [Gene ID:854203]
HIR2 Hir2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
34YBR248C5 [Gene ID:852550]
HIS7 His7p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
35YMR251W-A32 [Gene ID:855293]
HOR7 Hor7p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
36YDR399W14 [Gene ID:852008]
HPT1 HGPRTase ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
37YLL026W23 [Gene ID:850633]
HSP104 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
38YBR072W32 [Gene ID:852364]
HSP26 Hsp26p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
39YFR053C23 [Gene ID:850614]
HXK1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
40YOR136W14 [Gene ID:854303]
IDH2 Idh2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
41YKL103C23 [Gene ID:853758]
LAP4 Lap4p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
42YGR121C14 [Gene ID:853019]
MEP1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
43YNL142W23 [Gene ID:855580]
MEP2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
44YIL051C5 [Gene ID:854760]
MMF1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
45YML128C23 [Gene ID:854911]
MSC1 Msc1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
46YNL015W32 [Gene ID:855717]
PBI2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
47YNL214W5 [Gene ID:855507]
PEX17 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
48YMR105C23 [Gene ID:855131]
PGM2 Pgm2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
49YEL060C32 [Gene ID:856649]
PRB1 Prb1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
50YKR093W41 [Gene ID:853968]
PTR2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
51YLR142W5 [Gene ID:850833]
PUT1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
52YGL062W32 [Gene ID:852818]
PYC1 Pyc1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
53YIL066C5 [Gene ID:854744]
RNR3 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
54YPL220W14 [Gene ID:855881]
RPL1A L1A ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
55YGL135W5 [Gene ID:852742]
RPL1B L1B ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
56YBL087C32 [Gene ID:852191]
RPL23A Rpl23ap ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
57YER117W32 [Gene ID:856853]
RPL23B Rpl23bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
58YGR034W14 [Gene ID:852922]
RPL26B Rpl26bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
59YFR031C-A23 [Gene ID:850590]
RPL2A Rpl2ap ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
60YOR063W5 [Gene ID:854229]
RPL3 Rpl3p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
61YIL052C23 [Gene ID:854759]
RPL34B L34B ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
62YLR185W5 [Gene ID:850882]
RPL37A Rpl37ap ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
63YKR094C14 [Gene ID:853969]
RPL40B L40B ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
64YHR141C5 [Gene ID:856544]
RPL42B Rpl42bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
65YPL131W5 [Gene ID:855972]
RPL5 Rpl5p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
66YGL147C5 [Gene ID:852730]
RPL9A Rpl9ap ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
67YDL130W14 [Gene ID:851427]
RPP1B Rpp1bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
68YDR382W14 [Gene ID:851990]
RPP2B Rpp2bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
69YML026C32 [Gene ID:854982]
RPS18B Rps18bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
70YML063W14 [Gene ID:854939]
RPS1B Rps1bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
71YLR367W14 [Gene ID:851082]
RPS22B Rps22bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
72YPR132W23 [Gene ID:856250]
RPS23B Rps23bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
73YIL069C14 [Gene ID:854741]
RPS24B Rps24bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
74YLR287C-A23 [Gene ID:850994]
RPS30A Rps30ap ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
75YOR182C23 [Gene ID:854354]
RPS30B Rps30bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
76YHR203C5 [Gene ID:856610]
RPS4B Rps4bp ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
77YDL204W5 [Gene ID:851323]
RTN2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
78YER081W14 [Gene ID:856814]
SER3 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
79YLR058C14 [Gene ID:850747]
SHM2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
80YML034W5 [Gene ID:854974]
SRC1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
81YKL086W5 [Gene ID:853776]
SRX1 Srx1p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
82YLR237W14 [Gene ID:850938]
THI7 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
83YDR453C23 [Gene ID:852064]
TSA2 Tsa2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
84YLL039C23 [Gene ID:850620]
UBI4 Ubi4p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
85YER151C5 [Gene ID:856895]
UBP3 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
86YGR019W14 [Gene ID:852902]
UGA1 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
87YKL119C5 [Gene ID:853741]
VPH2 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
88YAL061W23 [Gene ID:851238]
BDH2 Bdh2p ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
89YBR139W14 [Gene ID:852436]
YBR139W ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
90YEL007W5 [Gene ID:856711]
YEL007W ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
91YER156C5 [Gene ID:856900]
YER156C ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
92YGL036W14 [Gene ID:852847]
YGL036W ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
93YHR087W32 [Gene ID:856487]
RTC3 ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
94YJL144W23 [Gene ID:853297]
YJL144W ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
95YPL150W5 [Gene ID:855953]
YPL150W ( Saccharomyces cerevisiae S288c )Taxonomy id: 559292
96YJL056C5 [Gene ID:853390]
ZAP1 Zap1p [Saccharomyces cerevisiae S288c ]Taxonomy id: 559292

§ Panel component ID.
Protocol
This assay is conducted in 384-well plates. From a screen of the whole yeast GFP collection, about 106 GFP clones were identified as responsive to rapamycin. 96 of these rapamycin responsive GFP clones (RapaGFP clones) were arrayed in a 96-well plate and used to screen against the active compounds in dose response analysis. 1 microL yeast cells from the source 96-well plate are transferred into a 96-well plate containing 150 microL SCD in each well and grown overnight. The cultures are diluted 2 fold, and continue to incubate additional 1 hr. 10 microL culture are added to a 384-well assay plate by the Biomek Span-8 (Beckman Coulter, USA) in triplicate. 10 microL SCD media supplemented with 0.03% pluoronic F-68 containing the appropriate concentration compounds are added using the Nanoquot (BioTek, USA) dispenser. The assay plates are incubated at 30 degrees C for 3hrs and read by HT flow cytometry.
Response of the protein expression was assessed by comparing the GFP measurement (Median Channel Fluorescence, MCF) in presence of the tester compound compared versus the solvent (DMSO);
Ratio = CmpdMCF/DMSOMCF
Active compounds either had a ratio greater than 1.5 or less than 0.66, and for these compounds the individual strain PUBCHEM_ACTIVITYSCORE were calculated based on these different cutoff by the following equation:
Individual SCORE = |Cutoff - Ratio|*100
For compounds with Ratio greater than 2, the PUBCHEM_ACTIVITYSCORE of 100 was assigned. The overall PUBCHEM_ACTIVITYSCORE was based on the maximum individual Score and the average individual Score in order to emphasize the compound that created the maximum response over the least number of different strains, as calculated by the following equation:
Overall Score = Maximum Individual Score - Average Individual Score
Comment
Abbreviations: microL for microliters, hr for hours, HT for high-throughput
Result Definitions
Show more
TIDNameDescriptionPID§Panel TargetsHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
ScoreThe BioAssay activity ranking scoreInteger
1YMR120C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain1Gene ID: 855149Outcome
2YMR120C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain1Integer
3YMR120C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO1Float
4YCL025C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain2Gene ID: 850333Outcome
5YCL025C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain2Integer
6YCL025C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO2Float
7YLR109W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain3Gene ID: 850799Outcome
8YLR109W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain3Integer
9YLR109W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO3Float
10YHR018C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain4Gene ID: 856411Outcome
11YHR018C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain4Integer
12YHR018C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO4Float
13YPR145W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain5Gene ID: 856268Outcome
14YPR145W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain5Integer
15YPR145W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO5Float
16YJR148W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain6Gene ID: 853613Outcome
17YJR148W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain6Integer
18YJR148W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO6Float
19YAL060W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain7Gene ID: 851239Outcome
20YAL060W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain7Integer
21YAL060W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO7Float
22YEL063C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain8Gene ID: 856646Outcome
23YEL063C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain8Integer
24YEL063C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO8Float
25YPL111W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain9Gene ID: 855993Outcome
26YPL111W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain9Integer
27YPL111W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO9Float
28YIL043C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain10Gene ID: 854768Outcome
29YIL043C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain10Integer
30YIL043C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO10Float
31YCR002C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain11Gene ID: 850358Outcome
32YCR002C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain11Integer
33YCR002C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO11Float
34YCL064C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain12Gene ID: 850295Outcome
35YCL064C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain12Integer
36YCL064C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO12Float
37YNR001C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain13Gene ID: 855732Outcome
38YNR001C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain13Integer
39YNR001C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO13Float
40YCR005C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain14Gene ID: 850361Outcome
41YCR005C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain14Integer
42YCR005C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO14Float
43YGR088W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain15Gene ID: 852979Outcome
44YGR088W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain15Integer
45YGR088W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO15Float
46YNL112W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain16Gene ID: 855611Outcome
47YNL112W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain16Integer
48YNL112W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO16Float
49YHR144C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain17Gene ID: 856548Outcome
50YHR144C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain17Integer
51YHR144C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO17Float
52YOR173W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain18Gene ID: 854344Outcome
53YOR173W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain18Integer
54YOR173W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO18Float
55YOL052C-A_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain19Gene ID: 854104Outcome
56YOL052C-A_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain19Integer
57YOL052C-A_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO19Float
58YPL265W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain20Gene ID: 855863Outcome
59YPL265W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain20Integer
60YPL265W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO20Float
61YEL071W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain21Gene ID: 856638Outcome
62YEL071W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain21Integer
63YEL071W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO21Float
64YBR208C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain22Gene ID: 852507Outcome
65YBR208C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain22Integer
66YBR208C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO22Float
67YNL068C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain23Gene ID: 855656Outcome
68YNL068C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain23Integer
69YNL068C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO23Float
70YHL021C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain24Gene ID: 856365Outcome
71YHL021C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain24Integer
72YHL021C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO24Float
73YDR070C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain25Gene ID: 851642Outcome
74YDR070C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain25Integer
75YDR070C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO25Float
76YKR039W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain26Gene ID: 853912Outcome
77YKR039W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain26Integer
78YKR039W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO26Float
79YMR307W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain27Gene ID: 855355Outcome
80YMR307W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain27Integer
81YMR307W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO27Float
82YPR184W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain28Gene ID: 856314Outcome
83YPR184W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain28Integer
84YPR184W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO28Float
85YOR375C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain29Gene ID: 854557Outcome
86YOR375C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain29Integer
87YOR375C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO29Float
88YML004C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain30Gene ID: 855009Outcome
89YML004C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain30Integer
90YML004C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO30Float
91YOR371C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain31Gene ID: 854553Outcome
92YOR371C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain31Integer
93YOR371C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO31Float
94YDL205C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain32Gene ID: 851322Outcome
95YDL205C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain32Integer
96YDL205C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO32Float
97YOR038C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain33Gene ID: 854203Outcome
98YOR038C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain33Integer
99YOR038C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO33Float
100YBR248C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain34Gene ID: 852550Outcome
101YBR248C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain34Integer
102YBR248C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO34Float
103YMR251W-A_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain35Gene ID: 855293Outcome
104YMR251W-A_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain35Integer
105YMR251W-A_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO35Float
106YDR399W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain36Gene ID: 852008Outcome
107YDR399W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain36Integer
108YDR399W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO36Float
109YLL026W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain37Gene ID: 850633Outcome
110YLL026W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain37Integer
111YLL026W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO37Float
112YBR072W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain38Gene ID: 852364Outcome
113YBR072W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain38Integer
114YBR072W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO38Float
115YFR053C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain39Gene ID: 850614Outcome
116YFR053C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain39Integer
117YFR053C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO39Float
118YOR136W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain40Gene ID: 854303Outcome
119YOR136W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain40Integer
120YOR136W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO40Float
121YKL103C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain41Gene ID: 853758Outcome
122YKL103C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain41Integer
123YKL103C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO41Float
124YGR121C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain42Gene ID: 853019Outcome
125YGR121C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain42Integer
126YGR121C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO42Float
127YNL142W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain43Gene ID: 855580Outcome
128YNL142W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain43Integer
129YNL142W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO43Float
130YIL051C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain44Gene ID: 854760Outcome
131YIL051C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain44Integer
132YIL051C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO44Float
133YML128C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain45Gene ID: 854911Outcome
134YML128C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain45Integer
135YML128C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO45Float
136YNL015W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain46Gene ID: 855717Outcome
137YNL015W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain46Integer
138YNL015W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO46Float
139YNL214W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain47Gene ID: 855507Outcome
140YNL214W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain47Integer
141YNL214W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO47Float
142YMR105C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain48Gene ID: 855131Outcome
143YMR105C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain48Integer
144YMR105C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO48Float
145YEL060C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain49Gene ID: 856649Outcome
146YEL060C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain49Integer
147YEL060C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO49Float
148YKR093W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain50Gene ID: 853968Outcome
149YKR093W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain50Integer
150YKR093W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO50Float
151YLR142W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain51Gene ID: 850833Outcome
152YLR142W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain51Integer
153YLR142W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO51Float
154YGL062W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain52Gene ID: 852818Outcome
155YGL062W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain52Integer
156YGL062W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO52Float
157YIL066C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain53Gene ID: 854744Outcome
158YIL066C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain53Integer
159YIL066C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO53Float
160YPL220W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain54Gene ID: 855881Outcome
161YPL220W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain54Integer
162YPL220W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO54Float
163YGL135W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain55Gene ID: 852742Outcome
164YGL135W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain55Integer
165YGL135W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO55Float
166YBL087C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain56Gene ID: 852191Outcome
167YBL087C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain56Integer
168YBL087C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO56Float
169YER117W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain57Gene ID: 856853Outcome
170YER117W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain57Integer
171YER117W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO57Float
172YGR034W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain58Gene ID: 852922Outcome
173YGR034W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain58Integer
174YGR034W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO58Float
175YFR031C-A_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain59Gene ID: 850590Outcome
176YFR031C-A_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain59Integer
177YFR031C-A_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO59Float
178YOR063W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain60Gene ID: 854229Outcome
179YOR063W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain60Integer
180YOR063W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO60Float
181YIL052C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain61Gene ID: 854759Outcome
182YIL052C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain61Integer
183YIL052C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO61Float
184YLR185W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain62Gene ID: 850882Outcome
185YLR185W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain62Integer
186YLR185W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO62Float
187YKR094C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain63Gene ID: 853969Outcome
188YKR094C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain63Integer
189YKR094C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO63Float
190YHR141C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain64Gene ID: 856544Outcome
191YHR141C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain64Integer
192YHR141C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO64Float
193YPL131W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain65Gene ID: 855972Outcome
194YPL131W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain65Integer
195YPL131W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO65Float
196YGL147C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain66Gene ID: 852730Outcome
197YGL147C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain66Integer
198YGL147C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO66Float
199YDL130W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain67Gene ID: 851427Outcome
200YDL130W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain67Integer
201YDL130W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO67Float
202YDR382W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain68Gene ID: 851990Outcome
203YDR382W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain68Integer
204YDR382W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO68Float
205YML026C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain69Gene ID: 854982Outcome
206YML026C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain69Integer
207YML026C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO69Float
208YML063W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain70Gene ID: 854939Outcome
209YML063W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain70Integer
210YML063W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO70Float
211YLR367W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain71Gene ID: 851082Outcome
212YLR367W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain71Integer
213YLR367W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO71Float
214YPR132W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain72Gene ID: 856250Outcome
215YPR132W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain72Integer
216YPR132W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO72Float
217YIL069C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain73Gene ID: 854741Outcome
218YIL069C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain73Integer
219YIL069C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO73Float
220YLR287C-A_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain74Gene ID: 850994Outcome
221YLR287C-A_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain74Integer
222YLR287C-A_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO74Float
223YOR182C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain75Gene ID: 854354Outcome
224YOR182C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain75Integer
225YOR182C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO75Float
226YHR203C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain76Gene ID: 856610Outcome
227YHR203C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain76Integer
228YHR203C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO76Float
229YDL204W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain77Gene ID: 851323Outcome
230YDL204W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain77Integer
231YDL204W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO77Float
232YER081W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain78Gene ID: 856814Outcome
233YER081W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain78Integer
234YER081W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO78Float
235YLR058C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain79Gene ID: 850747Outcome
236YLR058C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain79Integer
237YLR058C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO79Float
238YML034W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain80Gene ID: 854974Outcome
239YML034W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain80Integer
240YML034W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO80Float
241YKL086W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain81Gene ID: 853776Outcome
242YKL086W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain81Integer
243YKL086W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO81Float
244YLR237W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain82Gene ID: 850938Outcome
245YLR237W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain82Integer
246YLR237W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO82Float
247YDR453C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain83Gene ID: 852064Outcome
248YDR453C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain83Integer
249YDR453C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO83Float
250YLL039C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain84Gene ID: 850620Outcome
251YLL039C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain84Integer
252YLL039C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO84Float
253YER151C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain85Gene ID: 856895Outcome
254YER151C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain85Integer
255YER151C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO85Float
256YGR019W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain86Gene ID: 852902Outcome
257YGR019W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain86Integer
258YGR019W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO86Float
259YKL119C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain87Gene ID: 853741Outcome
260YKL119C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain87Integer
261YKL119C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO87Float
262YAL061W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain88Gene ID: 851238Outcome
263YAL061W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain88Integer
264YAL061W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO88Float
265YBR139W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain89Gene ID: 852436Outcome
266YBR139W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain89Integer
267YBR139W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO89Float
268YEL007W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain90Gene ID: 856711Outcome
269YEL007W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain90Integer
270YEL007W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO90Float
271YER156C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain91Gene ID: 856900Outcome
272YER156C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain91Integer
273YER156C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO91Float
274YGL036W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain92Gene ID: 852847Outcome
275YGL036W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain92Integer
276YGL036W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO92Float
277YHR087W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain93Gene ID: 856487Outcome
278YHR087W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain93Integer
279YHR087W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO93Float
280YJL144W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain94Gene ID: 853297Outcome
281YJL144W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain94Integer
282YJL144W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO94Float
283YPL150W_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain95Gene ID: 855953Outcome
284YPL150W_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain95Integer
285YPL150W_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO95Float
286YJL056C_OutcomePUBCHEM Outcome for GFP-tagged protein expression in this yeast strain96Gene ID: 853390Outcome
287YJL056C_ScorePUBCHEM Score for GFP-tagged protein expression in this yeast strain96Integer
288YJL056C_RatioToDMSORatio of GFP-tagged protein expression in presence of test compound compared with in presence of DMSO96Float
Additional Information
Grant Number: 1R03 MH086450-01

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