|Inhibition of human GHS-R1a - BioAssay Summary
This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit. ..more
BioActive Compounds: 29
Title: Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.
Abstract: This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
ChEMBL Assay Type: Binding
ChEMBL Assay Data Source: Scientific Literature
ChEMBL Target ID: 11536
ChEMBL target type: Target is a single protein chain
* Activity Concentration.
Data Table (Concise)