1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases. ..more
Target
| Sequence: RecName: Full=Alpha-galactosidase; AltName: Full=Melibiase Description ..   Protein Family: Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases Comment .. Related Protein 3D Structures |
Tested Compounds:
Description:
Title: Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles.
Abstract: 1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases.
(PMID: 15979309)
Abstract: 1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases.
(PMID: 15979309)
Categorized Comment
ChEMBL Assay Type: Binding
ChEMBL Assay Data Source: Scientific Literature
ChEMBL Target ID: 100197
ChEMBL target type: Target is a single protein chain
ChEMBL Assay Data Source: Scientific Literature
ChEMBL Target ID: 100197
ChEMBL target type: Target is a single protein chain
Result Definitions
| TID | Name | Description | Histogram | Type | Unit | |
|---|---|---|---|---|---|---|
| Outcome | The BioAssay activity outcome | Outcome | ||||
| 1 | Inhibition activity comment | Inhibition activity comment | String | |||
| 2 | Inhibition standard flag | Inhibition standard flag |  | Integer | ||
| 3 | Inhibition qualifier | Inhibition qualifier | String | |||
| 4 | Inhibition published value | Inhibition published value | | Float | % | |
| 5 | Inhibition standard value | Inhibition standard value | | Float | % |
Data Table (Concise)
Classification
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