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BioAssay: AID 212

NCI In Vivo Anticancer Drug Screen. Data for tumor model Colon Carcinoma 38 (subcutaneous) in B6D2F1 (BDF1) mice

The antitumor activity of compounds was measured in mice bearing transplantable tumors. Survival or tumor size were measured and the results are expressed as the measurement made in the treated group (T) divided by the measurement made in the vehicle treated control group (C). The tumor model used in this assay is Colon Carcinoma 38 (subcutaneous) in B6D2F1 (BDF1) mice ..more
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 Tested Compounds
 Tested Compounds
All(1135)
 
 
Active(306)
 
 
Inactive(502)
 
 
Inconclusive(334)
 
 
 Tested Substances
 Tested Substances
All(1251)
 
 
Active(341)
 
 
Inactive(546)
 
 
Inconclusive(364)
 
 
 Related BioAssays
 Related BioAssays
AID: 212
Data Source: DTP/NCI
Deposit Date: 2004-08-15
Modify Date: 2005-08-11

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 306
Description:
The antitumor activity of compounds was measured in mice bearing transplantable tumors. Survival or tumor size were measured and the results are expressed as the measurement made in the treated group (T) divided by the measurement made in the vehicle treated control group (C). The tumor model used in this assay is Colon Carcinoma 38 (subcutaneous) in B6D2F1 (BDF1) mice
Comment
These data are a subset of the data from the NCI In Vivo anticancer drug screen. Compounds are identified by the NCI NSC number.
Compounds with T/C(tcprcnt) >= 150% were considered active. Activity score was based on increasing values of tcprcnt.
Categorized Comment - additional comments and annotations
From PubChem:
Assay Test Type: In vivo
Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
ScoreThe BioAssay activity ranking scoreInteger
1scheduleDosing schedule and routeString
2endpointEndpoint measuredString
3vehicleVehicle used to administer the compoundString
4doseAmount for each doseString
5tcprcntresult for treated animals compared to vehicle treated controls (%)Float
6toxicityToxicity ObservationString

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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