Tested in vitro for the inhibition constant against rat small intestinal sucrase - BioAssay Summary
Tested in vitro for the inhibition constant against rat small intestinal sucrase ..more
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 Tested Compounds
 Tested Compounds
All(18)
 
 
Active(18)
 
 
 Tested Substances
 Tested Substances
All(18)
 
 
Active(18)
 
 
 Related BioAssays
 Related BioAssays
Table of Contents
AID: 208987
Data Source: ChEMBL (206289)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2013-04-26

Data Table (Complete):           Active    All
BioActive Compounds: 18
Description:
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Tested in vitro for the inhibition constant against rat small intestinal sucrase
Comment
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Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 12200
Target Type: SINGLE PROTEIN
Pref Name: Sucrase-isomaltase
Description: Sucrase-isomaltase, intestinal
Organism: Rattus norvegicus
Tax ID: 10116
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
ChEMBL target type: Target is a single protein chain


Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 3
First Page: 355
Last Page: 360
Categorized Comment
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ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature

Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Ki*Ki PubChem standard valueFloatμM
2BEIBinding Efficiency Index(nM)Float
3SEISurface Efficiency Index(nM)Float
4Ki activity commentKi activity commentString
5Ki standard flagKi standard flagInteger
6Ki qualifierKi qualifierString
7Ki published valueKi published valueFloatnM
8Ki standard valueKi standard valueFloatnM
* Activity Concentration.

Data Table (Concise)
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