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BioAssay: AID 199948

Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gamma

Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gamma ..more
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 Tested Compounds
 Tested Compounds
All(9)
 
 
Active(9)
 
 
 Tested Substances
 Tested Substances
All(9)
 
 
Active(9)
 
 
 Related BioAssays
 Related BioAssays
AID: 199948
Data Source: ChEMBL (197222)
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2013-11-11

Data Table ( Complete ):           Active    All
Target
Sequence: RecName: Full=Retinoic acid receptor RXR-gamma; AltName: Full=Nuclear receptor subfamily 2 group B member 3; AltName: Full=Retinoid X receptor gamma
Description ..   
Protein Family: The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
Comment ..   

Gene:RXRG     Related Protein 3D Structures     More BioActivity Data..
BioActive Compounds: 9
Description:
Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gamma
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.



Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 18
First Page: 2393
Last Page: 2398
Categorized Comment
ChEMBL Assay Type: Binding

ChEMBL Assay Data Source: Scientific Literature

ChEMBL Assay Cell Type: CV-1

ChEMBL Target ID: 12793

ChEMBL Target Type: Target is a single protein chain

Result Definitions
Show more
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1EC50*EC50 PubChem standard valueFloatμM
2BEIBinding Efficiency Index(nM)Float
3SEISurface Efficiency Index(nM)Float
4LELigand EfficiencyFloat
5LLELipophilic Ligand EfficiencyFloat
6EC50 activity commentEC50 activity commentString
7EC50 standard flagEC50 standard flagInteger
8EC50 qualifierEC50 qualifierString
9EC50 published valueEC50 published valueFloatnM
10EC50 standard valueEC50 standard valueFloatnM
11EC50 binding domainsEC50 binding domainsString

* Activity Concentration.

Data Table (Concise)
Classification
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