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BioAssay: AID 1982

Kinase inhibition selectivity assay for compound SID-48409448

Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity are poorly defined, and an important step toward understanding the relationship between selectivity, efficacy and safety is the exploration of how inhibitors interact with the human kinome. ..more
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 Tested Compounds
 Tested Compounds
All(1)
 
 
Unspecified(1)
 
 
 Tested Substances
 Tested Substances
All(1)
 
 
Unspecified(1)
 
 
 Related BioAssays
 Related BioAssays
AID: 1982
Data Source: Burnham Center for Chemical Genomics (BCCG-A228-NF-kB-kinase-Assay_10)
BioAssay Type: Panel
Depositor Category: NIH Molecular Libraries Screening Center Network
BioAssay Version:
Deposit Date: 2009-10-14
Modify Date: 2011-01-03

Data Table ( Complete ):           View All Data
Target
Tested Compound:
Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG)
Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA)
Network: NIH Molecular Libraries Probe Production Centers Network (MLPCN)
Grant Number: 1 X01 MH077633-01
Assay Provider: Dr. John C. Reed, Sanford-Burnham Medical Research Institute, San Diego CA

Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity are poorly defined, and an important step toward understanding the relationship between selectivity, efficacy and safety is the exploration of how inhibitors interact with the human kinome.
To investigate kinase inhibitory effect of the NF-kappaB inhibitor SID-48409448, we tested the compound in kinase assays which include a panel of 353 kinases kinome.
Panel Information
Kinase inhibition selectivity assay for compound SID-48409448
    Data Table(All)Show more
PID§NameSubstancePanel TargetsDescription
ActiveInactive
1AAK1 Inhibition Activity1AP2 associated kinase 1 [Homo sapiens] [gi:148277037]
Inhibition Activity against kinase AAK1 is provided
2ABL1 Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1 is provided
3ABL1(E255K) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(E255K) is provided
4ABL1(H396P) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(H396P) is provided
5ABL1(M351T) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(M351T) is provided
6ABL1(Q252H) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(Q252H) is provided
7ABL1(T315I) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(T315I) is provided
8ABL1(Y253F) Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens] [gi:62362414]
Inhibition Activity against kinase ABL1(Y253F) is provided
9ABL2 Inhibition Activity1v-abl Abelson murine leukemia viral oncogene homolog 2 isoform a [Homo sapiens] [gi:269847768]
Inhibition Activity against kinase ABL2 is provided
10ACVR1 Inhibition Activity1activin A type I receptor precursor [Homo sapiens] [gi:4501895]
Inhibition Activity against kinase ACVR1 is provided
11ACVR1B Inhibition Activity1activin A type IB receptor isoform a precursor [Homo sapiens] [gi:4757720]
Inhibition Activity against kinase ACVR1B is provided
12ACVR2A Inhibition Activity1activin A receptor, type IIA precursor [Homo sapiens] [gi:4501897]
Inhibition Activity against kinase ACVR2A is provided
13ACVR2B Inhibition Activity1activin A type IIB receptor precursor [Homo sapiens] [gi:116734708]
Inhibition Activity against kinase ACVR2B is provided
14ACVRL1 Inhibition Activity1activin A receptor type II-like 1 [Homo sapiens] [gi:116734712]
Inhibition Activity against kinase ACVRL1 is provided
15ADCK3 Inhibition Activity1chaperone, ABC1 activity of bc1 complex like precursor [Homo sapiens] [gi:34147522]
Inhibition Activity against kinase ADCK3 is provided
16ADCK4 Inhibition Activity1aarF domain containing kinase 4 [Homo sapiens] [gi:27363457]
Inhibition Activity against kinase ADCK4 is provided
17AKT1 Inhibition Activity1v-akt murine thymoma viral oncogene homolog 1 [Homo sapiens] [gi:62241011]
Inhibition Activity against kinase AKT1 is provided
18AKT2 Inhibition Activity1v-akt murine thymoma viral oncogene homolog 2 [Homo sapiens] [gi:4502023]
Inhibition Activity against kinase AKT2 is provided
19AKT3 Inhibition Activity1v-akt murine thymoma viral oncogene homolog 3 isoform 1 [Homo sapiens] [gi:4885549]
Inhibition Activity against kinase AKT3 is provided
20ALK Inhibition Activity1anaplastic lymphoma kinase Ki-1 [Homo sapiens] [gi:29029632]
Inhibition Activity against kinase ALK is provided
21AMPK-alpha1 Inhibition Activity1AMP-activated protein kinase alpha-1 [Homo sapiens] [gi:4115829]
Inhibition Activity against kinase AMPK-alpha1 is provided
22AMPK-alpha2 Inhibition Activity1AMP-activated protein kinase alpha 2 catalytic subunit [Homo sapiens] [gi:46877068]
Inhibition Activity against kinase AMPK-alpha2 is provided
23ANKK1 Inhibition Activity1ankyrin repeat and kinase domain containing 1 [Homo sapiens] [gi:30425444]
Inhibition Activity against kinase ANKK1 is provided
24ARK5 Inhibition Activity1AMPK-related protein kinase 5 [Homo sapiens] [gi:7662170]
Inhibition Activity against kinase ARK5 is provided
25AURKA Inhibition Activity1serine/threonine protein kinase 6 [Homo sapiens] [gi:38327562]
Inhibition Activity against kinase AURKA is provided
26AURKB Inhibition Activity1Aurora kinase B [Homo sapiens] [gi:127796234]
Inhibition Activity against kinase AURKB is provided
27AURKC Inhibition Activity1serine/threonine kinase 13 [Homo sapiens] [gi:3127068]
Inhibition Activity against kinase AURKC is provided
28AXL Inhibition Activity1AXL receptor tyrosine kinase isoform 2 [Homo sapiens] [gi:21536468]
Inhibition Activity against kinase AXL is provided
29BIKE Inhibition Activity1BMP-2 inducible kinase isoform b [Homo sapiens] [gi:38787904]
Inhibition Activity against kinase BIKE is provided
30BLK Inhibition Activity1B lymphoid tyrosine kinase [Homo sapiens] [gi:33469982]
Inhibition Activity against kinase BLK is provided
31BMPR1A Inhibition Activity1bone morphogenetic protein receptor, type IA precursor [Homo sapiens] [gi:41349437]
Inhibition Activity against kinase BMPR1A is provided
32BMPR2 Inhibition Activity1bone morphogenetic protein receptor type II precursor [Homo sapiens] [gi:15451916]
Inhibition Activity against kinase BMPR2 is provided
33BMX Inhibition Activity1BMX non-receptor tyrosine kinase [Homo sapiens] [gi:4502435]
Inhibition Activity against kinase BMX is provided
34BRAF Inhibition Activity1v-raf murine sarcoma viral oncogene homolog B1 [Homo sapiens] [gi:33188459]
Inhibition Activity against kinase BRAF is provided
35BRAF(V600E) Inhibition Activity1v-raf murine sarcoma viral oncogene homolog B1 [Homo sapiens] [gi:33188459]
Inhibition Activity against kinase BRAF(V600E) is provided
36BRSK1 Inhibition Activity1BR serine/threonine kinase 1 [Homo sapiens] [gi:24308326]
Inhibition Activity against kinase BRSK1 is provided
37BRSK2 Inhibition Activity1BR serine/threonine kinase 2 [Homo sapiens] [gi:116089335]
Inhibition Activity against kinase BRSK2 is provided
38BTK Inhibition Activity1Bruton agammaglobulinemia tyrosine kinase [Homo sapiens] [gi:4557377]
Inhibition Activity against kinase BTK is provided
39CAMK1 Inhibition Activity1calcium/calmodulin-dependent protein kinase I [Homo sapiens] [gi:4502553]
Inhibition Activity against kinase CAMK1 is provided
40CAMK1D Inhibition Activity1calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens] [gi:9966875]
Inhibition Activity against kinase CAMK1D is provided
41CAMK1G Inhibition Activity1calcium/calmodulin-dependent protein kinase IG [Homo sapiens] [gi:14196445]
Inhibition Activity against kinase CAMK1G is provided
42CAMK2A Inhibition Activity1calcium/calmodulin-dependent protein kinase IIA isoform 2 [Homo sapiens] [gi:25952118]
Inhibition Activity against kinase CAMK2A is provided
43CAMK2B Inhibition Activity1calcium/calmodulin-dependent protein kinase IIB isoform 1 [Homo sapiens] [gi:26051204]
Inhibition Activity against kinase CAMK2B is provided
44CAMK2D Inhibition Activity1multifunctional calcium/calmodulin-dependent protein kinase II delta2 isoform [Homo sapiens] [gi:4426595]
Inhibition Activity against kinase CAMK2D is provided
45CAMK2G Inhibition Activity1calcium/calmodulin-dependent protein kinase II gamma isoform 6 [Homo sapiens] [gi:26667211]
Inhibition Activity against kinase CAMK2G is provided
46CAMK4 Inhibition Activity1calcium/calmodulin-dependent protein kinase IV [Homo sapiens] [gi:4502557]
Inhibition Activity against kinase CAMK4 is provided
47CAMKK1 Inhibition Activity1calcium/calmodulin-dependent protein kinase 1 alpha isoform a [Homo sapiens] [gi:14150045]
Inhibition Activity against kinase CAMKK1 is provided
48CAMKK2 Inhibition Activity1calcium/calmodulin-dependent protein kinase kinase 2 beta isoform 1 [Homo sapiens] [gi:27437015]
Inhibition Activity against kinase CAMKK2 is provided
49CDC2L1 Inhibition Activity1cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] [gi:16332362]
Inhibition Activity against kinase CDC2L1 is provided
50CDC2L2 Inhibition Activity1cell division cycle 2-like 2 isoform 1 [Homo sapiens] [gi:148763347]
Inhibition Activity against kinase CDC2L2 is provided
51CDK11 Inhibition Activity1cell division cycle 2-like 6 (CDK8-like) [Homo sapiens] [gi:30387611]
Inhibition Activity against kinase CDK11 is provided
52CDK2 Inhibition Activity1cyclin-dependent kinase 2 isoform 1 [Homo sapiens] [gi:16936528]
Inhibition Activity against kinase CDK2 is provided
53CDK3 Inhibition Activity1cyclin-dependent kinase 3 [Homo sapiens] [gi:4557439]
Inhibition Activity against kinase CDK3 is provided
54CDK5 Inhibition Activity1cyclin-dependent kinase 5 [Homo sapiens] [gi:4826675]
Inhibition Activity against kinase CDK5 is provided
55CDK7 Inhibition Activity1cyclin-dependent kinase 7 [Homo sapiens] [gi:4502743]
Inhibition Activity against kinase CDK7 is provided
56CDK8 Inhibition Activity1cyclin-dependent kinase 8 [Homo sapiens] [gi:4502745]
Inhibition Activity against kinase CDK8 is provided
57CDK9 Inhibition Activity1cyclin-dependent kinase 9 [Homo sapiens] [gi:4502747]
Inhibition Activity against kinase CDK9 is provided
58CHEK1 Inhibition Activity1CHK1 checkpoint homolog [Homo sapiens] [gi:166295192]
Inhibition Activity against kinase CHEK1 is provided
59CIT Inhibition Activity1citron [Homo sapiens] [gi:32698688]
Inhibition Activity against kinase CIT is provided
60CLK1 Inhibition Activity1clk1; putative [gi:632964]
Inhibition Activity against kinase CLK1 is provided
61CLK2 Inhibition Activity1CDC-like kinase 2 [Homo sapiens] [gi:47717134]
Inhibition Activity against kinase CLK2 is provided
62CLK3 Inhibition Activity1CDC-like kinase 3 isoform b [Homo sapiens] [gi:153791372]
Inhibition Activity against kinase CLK3 is provided
63CLK4 Inhibition Activity1CDC-like kinase 4 [Homo sapiens] [gi:10190706]
Inhibition Activity against kinase CLK4 is provided
64CSF1R Inhibition Activity1colony stimulating factor 1 receptor precursor [Homo sapiens] [gi:27262659]
Inhibition Activity against kinase CSF1R is provided
65CSK Inhibition Activity1c-src tyrosine kinase [Homo sapiens] [gi:4758078]
Inhibition Activity against kinase CSK is provided
66CSNK1A1L Inhibition Activity1casein kinase 1, alpha 1-like [Homo sapiens] [gi:269846834]
Inhibition Activity against kinase CSNK1A1L is provided
67CSNK1D Inhibition Activity1casein kinase 1, delta isoform 2 [Homo sapiens] [gi:20544145]
Inhibition Activity against kinase CSNK1D is provided
68CSNK1E Inhibition Activity1casein kinase 1 epsilon [Homo sapiens] [gi:4503093]
Inhibition Activity against kinase CSNK1E is provided
69CSNK1G1 Inhibition Activity1casein kinase 1, gamma 1 [Homo sapiens] [gi:98986450]
Inhibition Activity against kinase CSNK1G1 is provided
70CSNK1G2 Inhibition Activity1casein kinase 1, gamma 2 [Homo sapiens] [gi:153791733]
Inhibition Activity against kinase CSNK1G2 is provided
71CSNK1G3 Inhibition Activity1casein kinase 1, gamma 3 isoform 1 [Homo sapiens] [gi:73532778]
Inhibition Activity against kinase CSNK1G3 is provided
72CSNK2A1 Inhibition Activity1casein kinase II alpha 1 subunit isoform a [Homo sapiens] [gi:4503095]
Inhibition Activity against kinase CSNK2A1 is provided
73CSNK2A2 Inhibition Activity1casein kinase 2, alpha prime polypeptide [Homo sapiens] [gi:4503097]
Inhibition Activity against kinase CSNK2A2 is provided
74DAPK1 Inhibition Activity1death-associated protein kinase 1 [Homo sapiens] [gi:89363047]
Inhibition Activity against kinase DAPK1 is provided
75DAPK2 Inhibition Activity1death-associated protein kinase 2 [Homo sapiens] [gi:14670383]
Inhibition Activity against kinase DAPK2 is provided
76DAPK3 Inhibition Activity1death-associated protein kinase 3 [Homo sapiens] [gi:4557511]
Inhibition Activity against kinase DAPK3 is provided
77DCAMKL1 Inhibition Activity1doublecortin and CaM kinase-like 1 [Homo sapiens] [gi:4758128]
Inhibition Activity against kinase DCAMKL1 is provided
78DCAMKL2 Inhibition Activity1doublecortin and CaM kinase-like 2 isoform b [Homo sapiens] [gi:306774095]
Inhibition Activity against kinase DCAMKL2 is provided
79DCAMKL3 Inhibition Activity1PREDICTED: similar to doublecortin and CaM kinase-like 3 [Homo sapiens] [gi:149589021]
Inhibition Activity against kinase DCAMKL3 is provided
80DDR1 Inhibition Activity1discoidin domain receptor family, member 1 isoform b [Homo sapiens] [gi:38327632]
Inhibition Activity against kinase DDR1 is provided
81DDR2 Inhibition Activity1protein-tyrosine kinase [Homo sapiens] [gi:433338]
Inhibition Activity against kinase DDR2 is provided
82DLK Inhibition Activity1mitogen-activated protein kinase kinase kinase 12 [Homo sapiens] [gi:301898341]
Inhibition Activity against kinase DLK is provided
83DMPK Inhibition Activity1myotonic dystrophy protein kinase isoform 2 [Homo sapiens] [gi:47059024]
Inhibition Activity against kinase DMPK is provided
84DMPK2 Inhibition Activity1CDC42 binding protein kinase gamma (DMPK-like) [Homo sapiens] [gi:156766068]
Inhibition Activity against kinase DMPK2 is provided
85DRAK1 Inhibition Activity1serine/threonine kinase 17a [Homo sapiens] [gi:109255245]
Inhibition Activity against kinase DRAK1 is provided
86DRAK2 Inhibition Activity1serine/threonine kinase 17b [Homo sapiens] [gi:4758194]
Inhibition Activity against kinase DRAK2 is provided
87DYRK1B Inhibition Activity1dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B isoform a [Homo sapiens] [gi:4758222]
Inhibition Activity against kinase DYRK1B is provided
88EGFR Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR is provided
89EGFR(E746-A750del) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(E746-A750del) is provided
90EGFR(G719C) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(G719C) is provided
91EGFR(G719S) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(G719S) is provided
92EGFR(L858R) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(L858R) is provided
93EGFR(L861Q) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(L861Q) is provided
94EGFR(S752-I759del) Inhibition Activity1epidermal growth factor receptor isoform a precursor [Homo sapiens] [gi:29725609]
Inhibition Activity against kinase EGFR(S752-I759del) is provided
95EPHA1 Inhibition Activity1ephrin receptor EphA1 [Homo sapiens] [gi:221316650]
Inhibition Activity against kinase EPHA1 is provided
96EPHA2 Inhibition Activity1ephrin receptor EphA2 [Homo sapiens] [gi:32967311]
Inhibition Activity against kinase EPHA2 is provided
97EPHA3 Inhibition Activity1ephrin receptor EphA3 isoform a precursor [Homo sapiens] [gi:21361241]
Inhibition Activity against kinase EPHA3 is provided
98EPHA4 Inhibition Activity1ephrin receptor EphA4 [Homo sapiens] [gi:4758280]
Inhibition Activity against kinase EPHA4 is provided
99EPHA5 Inhibition Activity1ephrin receptor EphA5 isoform a [Homo sapiens] [gi:221625401]
Inhibition Activity against kinase EPHA5 is provided
100EPHA6 Inhibition Activity1EPH receptor A6 isoform a [Homo sapiens] [gi:145312251]
Inhibition Activity against kinase EPHA6 is provided
101EPHA7 Inhibition Activity1ephrin receptor EphA7 [Homo sapiens] [gi:4758282]
Inhibition Activity against kinase EPHA7 is provided
102EPHA8 Inhibition Activity1EPH receptor A8 isoform 1 precursor [Homo sapiens] [gi:10140845]
Inhibition Activity against kinase EPHA8 is provided
103EPHB1 Inhibition Activity1ephrin receptor EphB1 precursor [Homo sapiens] [gi:4758284]
Inhibition Activity against kinase EPHB1 is provided
104EPHB2 Inhibition Activity1ephrin receptor EphB2 isoform 1 precursor [Homo sapiens] [gi:111118978]
Inhibition Activity against kinase EPHB2 is provided
105EPHB3 Inhibition Activity1ephrin receptor EphB3 precursor [Homo sapiens] [gi:17975768]
Inhibition Activity against kinase EPHB3 is provided
106EPHB4 Inhibition Activity1ephrin receptor EphB4 precursor [Homo sapiens] [gi:32528301]
Inhibition Activity against kinase EPHB4 is provided
107ERBB2 Inhibition Activity1erbB-2 isoform b [Homo sapiens] [gi:54792098]
Inhibition Activity against kinase ERBB2 is provided
108ERBB4 Inhibition Activity1v-erb-a erythroblastic leukemia viral oncogene homolog 4 isoform JM-a/CVT-2 precursor [Homo sapiens] [gi:110825958]
Inhibition Activity against kinase ERBB4 is provided
109ERK1 Inhibition Activity1mitogen-activated protein kinase 3 isoform 1 [Homo sapiens] [gi:91718899]
Inhibition Activity against kinase ERK1 is provided
110ERK2 Inhibition Activity1mitogen-activated protein kinase 1 [Homo sapiens] [gi:20986531]
Inhibition Activity against kinase ERK2 is provided
111ERK3 Inhibition Activity1mitogen-activated protein kinase 6 [Homo sapiens] [gi:4506091]
Inhibition Activity against kinase ERK3 is provided
112ERK4 Inhibition Activity1mitogen-activated protein kinase 4 [Homo sapiens] [gi:89276769]
Inhibition Activity against kinase ERK4 is provided
113ERK5 Inhibition Activity1mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] [gi:20986497]
Inhibition Activity against kinase ERK5 is provided
114ERK8 Inhibition Activity1mitogen-activated protein kinase 15 [Homo sapiens] [gi:95147356]
Inhibition Activity against kinase ERK8 is provided
115FER Inhibition Activity1fer (fps/fes related) tyrosine kinase [Homo sapiens] [gi:119964721]
Inhibition Activity against kinase FER is provided
116FES Inhibition Activity1V-FES feline sarcoma viral/V-FPS fujinami avian sarcoma viral oncogene homolog [Homo sapiens] [gi:4503687]
Inhibition Activity against kinase FES is provided
117FGFR1 Inhibition Activity1fibroblast growth factor receptor 1 isoform 3 precursor [Homo sapiens] [gi:13186234]
Inhibition Activity against kinase FGFR1 is provided
118FGFR2 Inhibition Activity1fibroblast growth factor receptor 2 isoform 2 precursor [Homo sapiens] [gi:221316638]
Inhibition Activity against kinase FGFR2 is provided
119FGFR3 Inhibition Activity1fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens] [gi:4503711]
Inhibition Activity against kinase FGFR3 is provided
120FGFR3(G697C) Inhibition Activity1fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens] [gi:4503711]
Inhibition Activity against kinase FGFR3(G697C) is provided
121FGFR4 Inhibition Activity1fibroblast growth factor receptor 4 isoform 2 precursor [Homo sapiens] [gi:47524177]
Inhibition Activity against kinase FGFR4 is provided
122FGR Inhibition Activity1proto-oncogene tyrosine-protein kinase FGR [Homo sapiens] [gi:4885235]
Inhibition Activity against kinase FGR is provided
123FLT1 Inhibition Activity1fms-related tyrosine kinase 1 [Homo sapiens] [gi:156104876]
Inhibition Activity against kinase FLT1 is provided
124FLT3 Inhibition Activity1fms-related tyrosine kinase 3 [Homo sapiens] [gi:121114304]
Inhibition Activity against kinase FLT3 is provided
125FLT3(D835H) Inhibition Activity1fms-related tyrosine kinase 3 [Homo sapiens] [gi:121114304]
Inhibition Activity against kinase FLT3(D835H) is provided
126FLT3(D835Y) Inhibition Activity1fms-related tyrosine kinase 3 [Homo sapiens] [gi:121114304]
Inhibition Activity against kinase FLT3(D835Y) is provided
127FLT3(ITD) Inhibition Activity1fms-related tyrosine kinase 3 [Homo sapiens] [gi:121114304]
Inhibition Activity against kinase FLT3(ITD) is provided
128FLT3(N841I) Inhibition Activity1fms-related tyrosine kinase 3 [Homo sapiens] [gi:121114304]
Inhibition Activity against kinase FLT3(N841I) is provided
129FLT4 Inhibition Activity1unnamed protein product [Homo sapiens] [gi:297050]
Inhibition Activity against kinase FLT4 is provided
130FRK Inhibition Activity1fyn-related kinase [Homo sapiens] [gi:4503787]
Inhibition Activity against kinase FRK is provided
131FYN Inhibition Activity1protein-tyrosine kinase fyn isoform b [Homo sapiens] [gi:23510362]
Inhibition Activity against kinase FYN is provided
132GAK Inhibition Activity1cyclin G associated kinase [Homo sapiens] [gi:157384971]
Inhibition Activity against kinase GAK is provided
133GSK3A Inhibition Activity1glycogen synthase kinase 3 alpha [Homo sapiens] [gi:49574532]
Inhibition Activity against kinase GSK3A is provided
134GSK3B Inhibition Activity1glycogen synthase kinase 3 beta [Homo sapiens] [gi:21361340]
Inhibition Activity against kinase GSK3B is provided
135HCK Inhibition Activity1hemopoietic cell kinase isoform p61HCK [Homo sapiens] [gi:30795229]
Inhibition Activity against kinase HCK is provided
136IGF1R Inhibition Activity1insulin-like growth factor 1 receptor precursor [Homo sapiens] [gi:4557665]
Inhibition Activity against kinase IGF1R is provided
137IKK-epsilon Inhibition Activity1IKK-related kinase epsilon [Homo sapiens] [gi:7661946]
Inhibition Activity against kinase IKK-epsilon is provided
138INSR Inhibition Activity1insulin receptor isoform Long precursor [Homo sapiens] [gi:119395736]
Inhibition Activity against kinase INSR is provided
139INSRR Inhibition Activity1insulin receptor-related receptor precursor [Homo sapiens] [gi:31657140]
Inhibition Activity against kinase INSRR is provided
140IRAK3 Inhibition Activity1interleukin-1 receptor-associated kinase 3 [Homo sapiens] [gi:216547519]
Inhibition Activity against kinase IRAK3 is provided
141ITK Inhibition Activity1IL2-inducible T-cell kinase [Homo sapiens] [gi:15718680]
Inhibition Activity against kinase ITK is provided
142JNK1 Inhibition Activity1mitogen-activated protein kinase 8 isoform JNK1 alpha1 [Homo sapiens] [gi:4506095]
Inhibition Activity against kinase JNK1 is provided
143JNK2 Inhibition Activity1mitogen-activated protein kinase 9 isoform JNK2 alpha1 [Homo sapiens] [gi:21237739]
Inhibition Activity against kinase JNK2 is provided
144JNK3 Inhibition Activity1mitogen-activated protein kinase 10 isoform 1 [Homo sapiens] [gi:4506081]
Inhibition Activity against kinase JNK3 is provided
145KIT Inhibition Activity1v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens] [gi:4557695]
Inhibition Activity against kinase KIT is provided
146KIT(D816V) Inhibition Activity1v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens] [gi:4557695]
Inhibition Activity against kinase KIT(D816V) is provided
147KIT(V559D) Inhibition Activity1v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens] [gi:4557695]
Inhibition Activity against kinase KIT(V559D) is provided
148LATS1 Inhibition Activity1LATS homolog 1 [Homo sapiens] [gi:4758666]
Inhibition Activity against kinase LATS1 is provided
149LATS2 Inhibition Activity1LATS, large tumor suppressor, homolog 2 [Homo sapiens] [gi:126507091]
Inhibition Activity against kinase LATS2 is provided
150LCK Inhibition Activity1lymphocyte-specific protein tyrosine kinase precursor [Homo sapiens] [gi:112789546]
Inhibition Activity against kinase LCK is provided
151LIMK1 Inhibition Activity1LIM domain kinase 1 [Homo sapiens] [gi:4505001]
Inhibition Activity against kinase LIMK1 is provided
152LIMK2 Inhibition Activity1LIM domain kinase 2 isoform 2a [Homo sapiens] [gi:5031869]
Inhibition Activity against kinase LIMK2 is provided
153LKB1 Inhibition Activity1serine/threonine protein kinase 11 [Homo sapiens] [gi:4507271]
Inhibition Activity against kinase LKB1 is provided
154LOK Inhibition Activity1protein kinase [Homo sapiens] [gi:4001688]
Inhibition Activity against kinase LOK is provided
155LTK Inhibition Activity1leukocyte tyrosine kinase isoform 2 precursor [Homo sapiens] [gi:46249416]
Inhibition Activity against kinase LTK is provided
156LYN Inhibition Activity1Yamaguchi sarcoma viral (v-yes-1) oncogene homolog isoform A [Homo sapiens] [gi:4505055]
Inhibition Activity against kinase LYN is provided
157MAP3K4 Inhibition Activity1mitogen-activated protein kinase kinase kinase 4 isoform a [Homo sapiens] [gi:55956904]
Inhibition Activity against kinase MAP3K4 is provided
158MAP3K5 Inhibition Activity1mitogen-activated protein kinase kinase kinase 5 [Homo sapiens] [gi:5174547]
Inhibition Activity against kinase MAP3K5 is provided
159MAP4K1 Inhibition Activity1mitogen-activated protein kinase kinase kinase kinase 1 isoform 1 [Homo sapiens] [gi:110611908]
Inhibition Activity against kinase MAP4K1 is provided
160MAP4K3 Inhibition Activity1mitogen-activated protein kinase kinase kinase kinase 3 [Homo sapiens] [gi:15451902]
Inhibition Activity against kinase MAP4K3 is provided
161MAP4K4 Inhibition Activity1mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] [gi:22035604]
Inhibition Activity against kinase MAP4K4 is provided
162MAP4K5 Inhibition Activity1mitogen-activated protein kinase kinase kinase kinase 5 [Homo sapiens] [gi:14589909]
Inhibition Activity against kinase MAP4K5 is provided
163MAPKAPK2 Inhibition Activity1mitogen-activated protein kinase-activated protein kinase 2 isoform 2 [Homo sapiens] [gi:32481209]
Inhibition Activity against kinase MAPKAPK2 is provided
164MARK1 Inhibition Activity1MAP/microtubule affinity-regulating kinase 1 [Homo sapiens] [gi:55665540]
Inhibition Activity against kinase MARK1 is provided
165MARK2 Inhibition Activity1MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens] [gi:86990441]
Inhibition Activity against kinase MARK2 is provided
166MARK3 Inhibition Activity1MAP/microtubule affinity-regulating kinase 3 isoform c [Homo sapiens] [gi:46852166]
Inhibition Activity against kinase MARK3 is provided
167MARK4 Inhibition Activity1MAP/microtubule affinity-regulating kinase 4 [Homo sapiens] [gi:33636756]
Inhibition Activity against kinase MARK4 is provided
168MEK1 Inhibition Activity1mitogen-activated protein kinase kinase 1 [Homo sapiens] [gi:5579478]
Inhibition Activity against kinase MEK1 is provided
169MEK2 Inhibition Activity1mitogen-activated protein kinase kinase 2 [Homo sapiens] [gi:13489054]
Inhibition Activity against kinase MEK2 is provided
170MEK3 Inhibition Activity1mitogen-activated protein kinase kinase 3 isoform A [Homo sapiens] [gi:21618347]
Inhibition Activity against kinase MEK3 is provided
171MEK4 Inhibition Activity1mitogen-activated protein kinase kinase 4 [Homo sapiens] [gi:4506889]
Inhibition Activity against kinase MEK4 is provided
172MEK6 Inhibition Activity1mitogen-activated protein kinase kinase 6 [Homo sapiens] [gi:14589900]
Inhibition Activity against kinase MEK6 is provided
173MELK Inhibition Activity1maternal embryonic leucine zipper kinase [Homo sapiens] [gi:7661974]
Inhibition Activity against kinase MELK is provided
174MERTK Inhibition Activity1novel cellular proto-oncogene [gi:505665]
Inhibition Activity against kinase MERTK is provided
175MET Inhibition Activity1met proto-oncogene isoform b precursor [Homo sapiens] [gi:42741655]
Inhibition Activity against kinase MET is provided
176MKNK1 Inhibition Activity1MAP kinase interacting serine/threonine kinase 1 [Homo sapiens] [gi:55957746]
Inhibition Activity against kinase MKNK1 is provided
177MKNK2 Inhibition Activity1map kinase-interacting kinase [Homo sapiens] [gi:6563264]
Inhibition Activity against kinase MKNK2 is provided
178MLCK Inhibition Activity1myosin light chain kinase 3 [Homo sapiens] [gi:146219832]
Inhibition Activity against kinase MLCK is provided
179MLK1 Inhibition Activity1mitogen-activated protein kinase kinase kinase 9 [Homo sapiens] [gi:52421790]
Inhibition Activity against kinase MLK1 is provided
180MLK2 Inhibition Activity1mitogen-activated protein kinase kinase kinase 10 [Homo sapiens] [gi:21735550]
Inhibition Activity against kinase MLK2 is provided
181MLK3 Inhibition Activity1mitogen-activated protein kinase kinase kinase 11 [Homo sapiens] [gi:4505195]
Inhibition Activity against kinase MLK3 is provided
182MRCKA Inhibition Activity1CDC42-binding protein kinase alpha isoform B [Homo sapiens] [gi:30089962]
Inhibition Activity against kinase MRCKA is provided
183MRCKB Inhibition Activity1CDC42-binding protein kinase beta [Homo sapiens] [gi:115527097]
Inhibition Activity against kinase MRCKB is provided
184MST1 Inhibition Activity1serine/threonine kinase 4 [Homo sapiens] [gi:5454096]
Inhibition Activity against kinase MST1 is provided
185MST2 Inhibition Activity1serine/threonine kinase 3 (STE20 homolog, yeast) [Homo sapiens] [gi:103471999]
Inhibition Activity against kinase MST2 is provided
186MST3 Inhibition Activity1serine/threonine kinase 24 isoform a [Homo sapiens] [gi:20070158]
Inhibition Activity against kinase MST3 is provided
187MST4 Inhibition Activity1serine/threonine protein kinase MST4 isoform 1 [Homo sapiens] [gi:15011880]
Inhibition Activity against kinase MST4 is provided
188MUSK Inhibition Activity1skeletal muscle receptor tyrosine kinase [Homo sapiens] [gi:5031927]
Inhibition Activity against kinase MUSK is provided
189MYLK Inhibition Activity1myosin light chain kinase isoform 2 [Homo sapiens] [gi:116008188]
Inhibition Activity against kinase MYLK is provided
190MYLK2 Inhibition Activity1skeletal myosin light chain kinase [Homo sapiens] [gi:14993776]
Inhibition Activity against kinase MYLK2 is provided
191MYO3A Inhibition Activity1myosin IIIA [Homo sapiens] [gi:145275208]
Inhibition Activity against kinase MYO3A is provided
192MYO3B Inhibition Activity1myosin IIIB isoform 2 [Homo sapiens] [gi:284172512]
Inhibition Activity against kinase MYO3B is provided
193NDR2 Inhibition Activity1serine/threonine kinase 38 like [Homo sapiens] [gi:24307971]
Inhibition Activity against kinase NDR2 is provided
194NEK1 Inhibition Activity1NIMA (never in mitosis gene a)-related kinase 1 [Homo sapiens] [gi:41872673]
Inhibition Activity against kinase NEK1 is provided
195NEK2 Inhibition Activity1NIMA (never in mitosis gene a)-related kinase 2 [Homo sapiens] [gi:4505373]
Inhibition Activity against kinase NEK2 is provided
196NEK5 Inhibition Activity1NIMA (never in mitosis gene a)-related kinase 5 [Homo sapiens] [gi:83627721]
Inhibition Activity against kinase NEK5 is provided
197NEK6 Inhibition Activity1putative serine-threonine protein kinase [Homo sapiens] [gi:19923407]
Inhibition Activity against kinase NEK6 is provided
198NEK7 Inhibition Activity1NIMA (never in mitosis gene a)-related kinase 7 [Homo sapiens] [gi:19424132]
Inhibition Activity against kinase NEK7 is provided
199NEK9 Inhibition Activity1NIMA related kinase 9 [Homo sapiens] [gi:222136641]
Inhibition Activity against kinase NEK9 is provided
200NLK Inhibition Activity1nemo-like kinase [Homo sapiens] [gi:149408126]
Inhibition Activity against kinase NLK is provided
201p38-alpha Inhibition Activity1mitogen-activated protein kinase 14 isoform 2 [Homo sapiens] [gi:20986512]
Inhibition Activity against kinase p38-alpha is provided
202p38-beta Inhibition Activity1mitogen-activated protein kinase 11 [Homo sapiens] [gi:20128774]
Inhibition Activity against kinase p38-beta is provided
203p38-gamma Inhibition Activity1p38gamma MAP Kinase [Homo sapiens] [gi:1772646]
Inhibition Activity against kinase p38-gamma is provided
204PAK1 Inhibition Activity1p21-activated kinase 1 isoform 2 [Homo sapiens] [gi:42794769]
Inhibition Activity against kinase PAK1 is provided
205PAK2 Inhibition Activity1p21-activated kinase 2 [Homo sapiens] [gi:32483399]
Inhibition Activity against kinase PAK2 is provided
206PAK3 Inhibition Activity1p21-activated kinase 3 isoform a [Homo sapiens] [gi:4505601]
Inhibition Activity against kinase PAK3 is provided
207PAK4 Inhibition Activity1p21-activated kinase 4 isoform 3 [Homo sapiens] [gi:62422559]
Inhibition Activity against kinase PAK4 is provided
208PAK6 Inhibition Activity1p21-activated kinase 6 [Homo sapiens] [gi:9910476]
Inhibition Activity against kinase PAK6 is provided
209PAK7/PAK5 Inhibition Activity1p21-activated kinase 7 [Homo sapiens] [gi:24308191]
Inhibition Activity against kinase PAK7/PAK5 is provided
210PCTK1 Inhibition Activity1PCTAIRE protein kinase 1 [Homo sapiens] [gi:5453860]
Inhibition Activity against kinase PCTK1 is provided
211PCTK2 Inhibition Activity1serine/threonine protein kinase [Homo sapiens] [gi:36617]
Inhibition Activity against kinase PCTK2 is provided
212PCTK3 Inhibition Activity1PCTAIRE protein kinase 3 isoform b [Homo sapiens] [gi:47078229]
Inhibition Activity against kinase PCTK3 is provided
213PDGFRA Inhibition Activity1platelet-derived growth factor receptor alpha precursor [Homo sapiens] [gi:5453870]
Inhibition Activity against kinase PDGFRA is provided
214PDGFRB Inhibition Activity1platelet-derived growth factor receptor beta precursor [Homo sapiens] [gi:4505683]
Inhibition Activity against kinase PDGFRB is provided
215PDPK1 Inhibition Activity13-phosphoinositide dependent protein kinase-1 isoform 1 [Homo sapiens] [gi:4505695]
Inhibition Activity against kinase PDPK1 is provided
216PFTK1 Inhibition Activity1PFTAIRE protein kinase 1 [Homo sapiens] [gi:6912584]
Inhibition Activity against kinase PFTK1 is provided
217PHKG1 Inhibition Activity1phosphorylase kinase gamma subunit 1 [Homo sapiens] [gi:5453882]
Inhibition Activity against kinase PHKG1 is provided
218PHKG2 Inhibition Activity1phosphorylase kinase, gamma 2 (testis) [Homo sapiens] [gi:4505785]
Inhibition Activity against kinase PHKG2 is provided
219PIK3CA Inhibition Activity1phosphoinositide-3-kinase, catalytic, alpha polypeptide [Homo sapiens] [gi:54792082]
Inhibition Activity against kinase PIK3CA is provided
220PIK3CA(E545K) Inhibition Activity1phosphoinositide-3-kinase, catalytic, alpha polypeptide [Homo sapiens] [gi:54792082]
Inhibition Activity against kinase PIK3CA(E545K) is provided
221PIM1 Inhibition Activity1pim-1 oncogene [Homo sapiens] [gi:4505811]
Inhibition Activity against kinase PIM1 is provided
222PIM2 Inhibition Activity1pim-2 oncogene [Homo sapiens] [gi:42821112]
Inhibition Activity against kinase PIM2 is provided
223PIM3 Inhibition Activity1pim-3 oncogene [Homo sapiens] [gi:224591416]
Inhibition Activity against kinase PIM3 is provided
224PIP5K1A Inhibition Activity168 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [Homo sapiens] [gi:1743873]
Inhibition Activity against kinase PIP5K1A is provided
225PIP5K2B Inhibition Activity1phosphatidylinositol-5-phosphate 4-kinase, type II, beta [Homo sapiens] [gi:4505819]
Inhibition Activity against kinase PIP5K2B is provided
226PKAC-alpha Inhibition Activity1cAMP-dependent protein kinase catalytic subunit alpha isoform 1 [Homo sapiens] [gi:4506055]
Inhibition Activity against kinase PKAC-alpha is provided
227PKAC-beta Inhibition Activity1cAMP-dependent protein kinase catalytic subunit beta isoform 2 [Homo sapiens] [gi:4506057]
Inhibition Activity against kinase PKAC-beta is provided
228PKMYT1 Inhibition Activity1protein kinase Myt1 isoform 2 [Homo sapiens] [gi:33383239]
Inhibition Activity against kinase PKMYT1 is provided
229PKN1 Inhibition Activity1protein kinase N1 isoform 1 [Homo sapiens] [gi:47132591]
Inhibition Activity against kinase PKN1 is provided
230PKN2 Inhibition Activity1protein kinase N2 [Homo sapiens] [gi:5453974]
Inhibition Activity against kinase PKN2 is provided
231PLK1 Inhibition Activity1polo-like kinase [Homo sapiens] [gi:21359873]
Inhibition Activity against kinase PLK1 is provided
232PLK3 Inhibition Activity1polo-like kinase 3 [Homo sapiens] [gi:41872374]
Inhibition Activity against kinase PLK3 is provided
233PLK4 Inhibition Activity1Sak [Homo sapiens] [gi:16215696]
Inhibition Activity against kinase PLK4 is provided
234PRKCD Inhibition Activity1protein kinase C, delta [Homo sapiens] [gi:31377782]
Inhibition Activity against kinase PRKCD is provided
235PRKCE Inhibition Activity1protein kinase C, epsilon [Homo sapiens] [gi:4885563]
Inhibition Activity against kinase PRKCE is provided
236PRKCH Inhibition Activity1protein kinase C, eta [Homo sapiens] [gi:28557781]
Inhibition Activity against kinase PRKCH is provided
237PRKCQ Inhibition Activity1protein kinase C, theta [Homo sapiens] [gi:5453976]
Inhibition Activity against kinase PRKCQ is provided
238PRKD1 Inhibition Activity1protein kinase D1 [Homo sapiens] [gi:115529463]
Inhibition Activity against kinase PRKD1 is provided
239PRKD2 Inhibition Activity1protein kinase D2 isoform A [Homo sapiens] [gi:19923468]
Inhibition Activity against kinase PRKD2 is provided
240PRKD3 Inhibition Activity1protein kinase D3 [Homo sapiens] [gi:5031689]
Inhibition Activity against kinase PRKD3 is provided
241PRKG1 Inhibition Activity1protein kinase, cGMP-dependent, type I isoform 2 [Homo sapiens] [gi:10835242]
Inhibition Activity against kinase PRKG1 is provided
242PRKG2 Inhibition Activity1protein kinase, cGMP-dependent, type II [Homo sapiens] [gi:5453978]
Inhibition Activity against kinase PRKG2 is provided
243PRKR Inhibition Activity1eukaryotic translation initiation factor 2-alpha kinase 2 [Homo sapiens] [gi:4506103]
Inhibition Activity against kinase PRKR is provided
244PRKX Inhibition Activity1protein kinase, X-linked [Homo sapiens] [gi:4826948]
Inhibition Activity against kinase PRKX is provided
245PTK2 Inhibition Activity1PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] [gi:24476013]
Inhibition Activity against kinase PTK2 is provided
246PTK2B Inhibition Activity1PTK2B protein tyrosine kinase 2 beta isoform b [Homo sapiens] [gi:27886588]
Inhibition Activity against kinase PTK2B is provided
247PTK6 Inhibition Activity1PTK6 protein tyrosine kinase 6 [Homo sapiens] [gi:5174647]
Inhibition Activity against kinase PTK6 is provided
248RAF1 Inhibition Activity1v-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens] [gi:4506401]
Inhibition Activity against kinase RAF1 is provided
249RET Inhibition Activity1ret proto-oncogene isoform c [Homo sapiens] [gi:10862701]
Inhibition Activity against kinase RET is provided
250RET(M918T) Inhibition Activity1ret proto-oncogene isoform c [Homo sapiens] [gi:10862701]
Inhibition Activity against kinase RET(M918T) is provided
251RIOK1 Inhibition Activity1RIO kinase 1 isoform 1 [Homo sapiens] [gi:23510356]
Inhibition Activity against kinase RIOK1 is provided
252RIOK3 Inhibition Activity1sudD suppressor of bimD6 homolog [Homo sapiens] [gi:22325377]
Inhibition Activity against kinase RIOK3 is provided
253RIPK1 Inhibition Activity1receptor (TNFRSF)-interacting serine-threonine kinase 1 [Homo sapiens] [gi:57242761]
Inhibition Activity against kinase RIPK1 is provided
254RIPK2 Inhibition Activity1receptor-interacting serine-threonine kinase 2 [Homo sapiens] [gi:4506537]
Inhibition Activity against kinase RIPK2 is provided
255ROS1 Inhibition Activity1proto-oncogene c-ros-1 protein precursor [Homo sapiens] [gi:19924165]
Inhibition Activity against kinase ROS1 is provided
256SgK085 Inhibition Activity1myosin light chain kinase family, member 4 [Homo sapiens] [gi:167466233]
Inhibition Activity against kinase SgK085 is provided
257SLK Inhibition Activity1serine/threonine kinase 2 [Homo sapiens] [gi:41281453]
Inhibition Activity against kinase SLK is provided
258SNARK Inhibition Activity1NUAK family, SNF1-like kinase, 2 [Homo sapiens] [gi:13569922]
Inhibition Activity against kinase SNARK is provided
259SNF1LK Inhibition Activity1SNF1-like kinase [Homo sapiens] [gi:116256471]
Inhibition Activity against kinase SNF1LK is provided
260SNF1LK2 Inhibition Activity1SNF1-like kinase 2 [Homo sapiens] [gi:38569460]
Inhibition Activity against kinase SNF1LK2 is provided
261SRC Inhibition Activity1proto-oncogene tyrosine-protein kinase SRC [Homo sapiens] [gi:4885609]
Inhibition Activity against kinase SRC is provided
262SRMS Inhibition Activity1src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [Homo sapiens] [gi:18250298]
Inhibition Activity against kinase SRMS is provided
263SRPK1 Inhibition Activity1SFRS protein kinase 1 [Homo sapiens] [gi:47419936]
Inhibition Activity against kinase SRPK1 is provided
264SRPK2 Inhibition Activity1serine kinase SRPK2 [Homo sapiens] [gi:1857944]
Inhibition Activity against kinase SRPK2 is provided
265STK16 Inhibition Activity1PKL12 protein [Homo sapiens] [gi:3367705]
Inhibition Activity against kinase STK16 is provided
266STK33 Inhibition Activity1serine/threonine kinase 33 [Homo sapiens] [gi:23943882]
Inhibition Activity against kinase STK33 is provided
267STK36 Inhibition Activity1serine/threonine kinase 36 [Homo sapiens] [gi:217330634]
Inhibition Activity against kinase STK36 is provided
268SYK Inhibition Activity1spleen tyrosine kinase [Homo sapiens] [gi:21361553]
Inhibition Activity against kinase SYK is provided
269TEC Inhibition Activity1tec protein tyrosine kinase [Homo sapiens] [gi:130977759]
Inhibition Activity against kinase TEC is provided
270TESK1 Inhibition Activity1testis-specific protein kinase 1 [Homo sapiens] [gi:66932999]
Inhibition Activity against kinase TESK1 is provided
271TGFBR1 Inhibition Activity1transforming growth factor, beta receptor I isoform 1 precursor [Homo sapiens] [gi:4759226]
Inhibition Activity against kinase TGFBR1 is provided
272TGFBR2 Inhibition Activity1transforming growth factor, beta receptor II isoform B precursor [Homo sapiens] [gi:67782324]
Inhibition Activity against kinase TGFBR2 is provided
273TIE1 Inhibition Activity1tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Homo sapiens] [gi:4885631]
Inhibition Activity against kinase TIE1 is provided
274TIE2 Inhibition Activity1TEK tyrosine kinase, endothelial precursor [Homo sapiens] [gi:88758596]
Inhibition Activity against kinase TIE2 is provided
275TLK1 Inhibition Activity1tousled-like kinase 1 [Homo sapiens] [gi:33636698]
Inhibition Activity against kinase TLK1 is provided
276TLK2 Inhibition Activity1tousled-like kinase 2 [Homo sapiens] [gi:6063019]
Inhibition Activity against kinase TLK2 is provided
277TNIK Inhibition Activity1TRAF2 and NCK interacting kinase [Homo sapiens] [gi:55741807]
Inhibition Activity against kinase TNIK is provided
278TNK1 Inhibition Activity1TNK1 protein [Homo sapiens] [gi:23273502]
Inhibition Activity against kinase TNK1 is provided
279TNK2 Inhibition Activity1tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens] [gi:58331191]
Inhibition Activity against kinase TNK2 is provided
280TNNI3K Inhibition Activity1TNNI3 interacting kinase isoform b [Homo sapiens] [gi:7705748]
Inhibition Activity against kinase TNNI3K is provided
281TRKA Inhibition Activity1neurotrophic tyrosine kinase, receptor, type 1 isoform 1 [Homo sapiens] [gi:59889558]
Inhibition Activity against kinase TRKA is provided
282TRKB Inhibition Activity1neurotrophic tyrosine kinase, receptor, type 2 isoform a precursor [Homo sapiens] [gi:21361306]
Inhibition Activity against kinase TRKB is provided
283TRKC Inhibition Activity1TrkC [gi:442390]
Inhibition Activity against kinase TRKC is provided
284TSSK1 Inhibition Activity1testis-specific serine kinase 1 [Homo sapiens] [gi:14042947]
Inhibition Activity against kinase TSSK1 is provided
285TTK Inhibition Activity1TTK protein kinase [Homo sapiens] [gi:23308722]
Inhibition Activity against kinase TTK is provided
286TXK Inhibition Activity1TXK tyrosine kinase [Homo sapiens] [gi:148596974]
Inhibition Activity against kinase TXK is provided
287TYRO3 Inhibition Activity1TYRO3 protein tyrosine kinase [Homo sapiens] [gi:27597078]
Inhibition Activity against kinase TYRO3 is provided
288VEGFR2 Inhibition Activity1kinase insert domain receptor (a type III receptor tyrosine kinase) [Homo sapiens] [gi:11321597]
Inhibition Activity against kinase VEGFR2 is provided
289WEE1 Inhibition Activity1wee1 tyrosine kinase [Homo sapiens] [gi:4507917]
Inhibition Activity against kinase WEE1 is provided
290YANK2 Inhibition Activity1serine/threonine kinase 32B [Homo sapiens] [gi:8923754]
Inhibition Activity against kinase YANK2 is provided
291YANK3 Inhibition Activity1serine/threonine kinase 32C [Homo sapiens] [gi:32455269]
Inhibition Activity against kinase YANK3 is provided
292YES Inhibition Activity1viral oncogene yes-1 homolog 1 [Homo sapiens] [gi:4885661]
Inhibition Activity against kinase YES is provided
293YSK1 Inhibition Activity1serine/threonine kinase 25 [Homo sapiens] [gi:21361358]
Inhibition Activity against kinase YSK1 is provided
294ZAK Inhibition Activity1MLK-related kinase isoform 2 [Homo sapiens] [gi:19526767]
Inhibition Activity against kinase ZAK is provided
295ZAP70 Inhibition Activity1zeta-chain associated protein kinase 70kDa isoform 2 [Homo sapiens] [gi:46488944]
Inhibition Activity against kinase ZAP70 is provided
296ABL1(F317I) Inhibition Activity1c-abl oncogene 1, receptor tyrosine kinase [gi:62362414]
Inhibition Activity against kinase ABL1(F317I) is provided
297ABL1(F317L) Inhibition Activity1c-abl oncogene 1, receptor tyrosine kinase [gi:62362414]
Inhibition Activity against kinase ABL1(F317L) is provided
298BMPR1B Inhibition Activity1bone morphogenetic protein receptor, type IB [gi:4502431]
Inhibition Activity against kinase BMPR1B is provided
299CDKL2 Inhibition Activity1cyclin-dependent kinase-like 2 (CDC2-related kinase) [gi:4505569]
Inhibition Activity against kinase CDKL2 is provided
300CHEK2 Inhibition Activity1CHK2 checkpoint homolog (S. pombe) [gi:54112407]
Inhibition Activity against kinase CHEK2 is provided
301EGFR(L747-E749del, A750P) Inhibition Activity1epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) [gi:29725609]
Inhibition Activity against kinase EGFR(L747-E749del, A750P) is provided
302EGFR(L747-S752del, P753S) Inhibition Activity1epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) [gi:29725609]
Inhibition Activity against kinase EGFR(L747-S752del, P753S) is provided
303EGFR(L747-T751del,Sins) Inhibition Activity1epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) [gi:29725609]
Inhibition Activity against kinase EGFR(L747-T751del,Sins) is provided
304FLT3(K663Q) Inhibition Activity1fms-related tyrosine kinase 3 [gi:121114304]
Inhibition Activity against kinase FLT3(K663Q) is provided
305GCN2(Kin.Dom.2,S808G) Inhibition Activity1eukaryotic translation initiation factor 2 alpha kinase 4 [gi:65287717]
Inhibition Activity against kinase GCN2(Kin.Dom.2,S808G) is provided
306HIPK1 Inhibition Activity1homeodomain interacting protein kinase 1 [gi:38201638]
Inhibition Activity against kinase HIPK1 is provided
307IKK-alpha Inhibition Activity1conserved helix-loop-helix ubiquitous kinase [gi:62241001]
Inhibition Activity against kinase IKK-alpha is provided
308IKK-beta Inhibition Activity1inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [gi:41352712]
Inhibition Activity against kinase IKK-beta is provided
309JAK1(Kin.Dom.1) Inhibition Activity1Janus kinase 1 [gi:102469034]
Inhibition Activity against kinase JAK1(Kin.Dom.1) is provided
310JAK1(Kin.Dom.2) Inhibition Activity1Janus kinase 1 [gi:102469034]
Inhibition Activity against kinase JAK1(Kin.Dom.2) is provided
311JAK2(Kin.Dom.2) Inhibition Activity1Janus kinase 2 [gi:4826776]
Inhibition Activity against kinase JAK2(Kin.Dom.2) is provided
312JAK3(Kin.Dom.2) Inhibition Activity1Janus kinase 3 [gi:47157315]
Inhibition Activity against kinase JAK3(Kin.Dom.2) is provided
313KIT(V559D,T670I) Inhibition Activity1v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog [gi:4557695]
Inhibition Activity against kinase KIT(V559D,T670I) is provided
314KIT(V559D,V654A) Inhibition Activity1v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog [gi:4557695]
Inhibition Activity against kinase KIT(V559D,V654A) is provided
315MAP3K3 Inhibition Activity1mitogen-activated protein kinase kinase kinase 3 [gi:42794765]
Inhibition Activity against kinase MAP3K3 is provided
316MAP4K2 Inhibition Activity1mitogen-activated protein kinase kinase kinase kinase 2 [gi:22035600]
Inhibition Activity against kinase MAP4K2 is provided
317MAPKAPK5 Inhibition Activity1mitogen-activated protein kinase-activated protein kinase 5 [gi:21237765]
Inhibition Activity against kinase MAPKAPK5 is provided
318MINK Inhibition Activity1misshapen-like kinase 1 (zebrafish) [gi:68161546]
Inhibition Activity against kinase MINK is provided
319MST1R Inhibition Activity1macrophage stimulating 1 receptor (c-met-related tyrosine kinase) [gi:153946393]
Inhibition Activity against kinase MST1R is provided
320p38-delta Inhibition Activity1mitogen-activated protein kinase 13 [gi:4506085]
Inhibition Activity against kinase p38-delta is provided
321PFTAIRE2 Inhibition Activity1PFTAIRE protein kinase 2 [gi:21040235]
Inhibition Activity against kinase PFTAIRE2 is provided
322PIK3C2B Inhibition Activity1phosphoinositide-3-kinase, class 2, beta polypeptide [gi:194097347]
Inhibition Activity against kinase PIK3C2B is provided
323PIK3CB Inhibition Activity1phosphoinositide-3-kinase, catalytic, beta polypeptide [gi:5453894]
Inhibition Activity against kinase PIK3CB is provided
324PIK3CD Inhibition Activity1phosphoinositide-3-kinase, catalytic, delta polypeptide [gi:156564405]
Inhibition Activity against kinase PIK3CD is provided
325PIK3CG Inhibition Activity1phosphoinositide-3-kinase, catalytic, gamma polypeptide [gi:21237725]
Inhibition Activity against kinase PIK3CG is provided
326RET(V804L) Inhibition Activity1ret proto-oncogene [gi:10862701]
Inhibition Activity against kinase RET(V804L) is provided
327RET(V804M) Inhibition Activity1ret proto-oncogene [gi:10862701]
Inhibition Activity against kinase RET(V804M) is provided
328RIOK2 Inhibition Activity1RIO kinase 2 (yeast) [gi:229331971]
Inhibition Activity against kinase RIOK2 is provided
329RIPK4 Inhibition Activity1receptor-interacting serine-threonine kinase 4 [gi:41327754]
Inhibition Activity against kinase RIPK4 is provided
330ROCK2 Inhibition Activity1Rho-associated, coiled-coil containing protein kinase 2 [gi:41872583]
Inhibition Activity against kinase ROCK2 is provided
331RPS6KA1(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 1 [gi:55743134]
Inhibition Activity against kinase RPS6KA1(Kin.Dom.1) is provided
332RPS6KA1(Kin.Dom.2) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 1 [gi:55743134]
Inhibition Activity against kinase RPS6KA1(Kin.Dom.2) is provided
333RPS6KA2(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 2 [gi:55743136]
Inhibition Activity against kinase RPS6KA2(Kin.Dom.1) is provided
334RPS6KA2(Kin.Dom.2) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 2 [gi:55743136]
Inhibition Activity against kinase RPS6KA2(Kin.Dom.2) is provided
335RPS6KA3(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 3 [gi:4759050]
Inhibition Activity against kinase RPS6KA3(Kin.Dom.1) is provided
336RPS6KA4(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 4 [gi:55743138]
Inhibition Activity against kinase RPS6KA4(Kin.Dom.1) is provided
337RPS6KA4(Kin.Dom.2) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 4 [gi:55743138]
Inhibition Activity against kinase RPS6KA4(Kin.Dom.2) is provided
338RPS6KA5(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 5 [gi:32528295]
Inhibition Activity against kinase RPS6KA5(Kin.Dom.1) is provided
339RPS6KA5(Kin.Dom.2) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 5 [gi:32528295]
Inhibition Activity against kinase RPS6KA5(Kin.Dom.2) is provided
340RPS6KA6(Kin.Dom.1) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 6 [gi:7657526]
Inhibition Activity against kinase RPS6KA6(Kin.Dom.1) is provided
341RPS6KA6(Kin.Dom.2) Inhibition Activity1ribosomal protein S6 kinase, 90kDa, polypeptide 6 [gi:7657526]
Inhibition Activity against kinase RPS6KA6(Kin.Dom.2) is provided
342SgK110 Inhibition Activity1similar to Putative uncharacterized serine/threonine-protein kinase SgK110 [gi:161783904]
Inhibition Activity against kinase SgK110 is provided
343SRPK3 Inhibition Activity1SFRS protein kinase 3 [gi:63025196]
Inhibition Activity against kinase SRPK3 is provided
344STK35 Inhibition Activity1serine/threonine kinase 35 [gi:260099625]
Inhibition Activity against kinase STK35 is provided
345TAK1 Inhibition Activity1mitogen-activated protein kinase kinase kinase 7 [gi:21735562]
Inhibition Activity against kinase TAK1 is provided
346TAOK1 Inhibition Activity1TAO kinase 1 [gi:45439370]
Inhibition Activity against kinase TAOK1 is provided
347TAOK3 Inhibition Activity1TAO kinase 3 [gi:148746218]
Inhibition Activity against kinase TAOK3 is provided
348TYK2(Kin.Dom.1) Inhibition Activity1tyrosine kinase 2 [gi:187608615]
Inhibition Activity against kinase TYK2(Kin.Dom.1) is provided
349TYK2(Kin.Dom.2) Inhibition Activity1tyrosine kinase 2 [gi:187608615]
Inhibition Activity against kinase TYK2(Kin.Dom.2) is provided
350ULK1 Inhibition Activity1unc-51-like kinase 1 (C. elegans) [gi:4507831]
Inhibition Activity against kinase ULK1 is provided
351ULK2 Inhibition Activity1unc-51-like kinase 2 (C. elegans) [gi:217330557]
Inhibition Activity against kinase ULK2 is provided
352ULK3 Inhibition Activity1unc-51-like kinase 3 (C. elegans) [gi:150456432]
Inhibition Activity against kinase ULK3 is provided
353WEE2 Inhibition Activity1WEE1 homolog 2 (S. pombe) [gi:254763343]
Inhibition Activity against kinase WEE2 is provided

§ Panel component ID.
Protocol
Kinase screening was done by Ambit Biosciences (San Diego, CA) using a standard protocol, adapted from Karaman, 2008, http://www.nature.com/nbt/journal/v26/n1/abs/nbt1358.html

Briefly,
1. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DNA for qPCR detection. In general, full-length constructs were used for small, single domain kinases, and catalytic domain constructs for large multidomain kinases.

2. For the binding assays, streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resins for kinase assays.
3. The liganded beads were blocked with excess biotin and washed with blocking buffer (SeaBlock (Pierce), 1% BSA, 0.05% Tween 20, 1 mM DTT) to remove unbound ligand and to reduce non-specific binding.
4. Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1X binding buffer (20% SeaBlock, 0.17X PBS, 0.05% Tween 20, 6 mM DTT).
5. Test compounds were prepared as 40X stocks in 100% DMSO and directly diluted into the assay. All reactions were performed in polypropylene 384-well plates in a final volume of 0.04 ml. The assay plates were incubated at room temperature with shaking for 1 hour and the affinity beads were washed with wash buffer (1X PBS, 0.05 % Tween 20). The beads were then re-suspended in elution buffer (1X PBS, 0.05 % Tween 20, 0.5 um non-biotinylated affinity ligand) and incubated at room temperature with shaking for 30 minutes. Each kinase was tested individually against compound CID-2858522 at final concentration of 10 uM.
6. The kinase concentration in the eluates was measured by qPCR.
7. Data is reported as %Ctrl, or Percent of Control (POC) where lower numbers indicate stronger hits. Any kinase showing 30% activity by the compound is considered as positive candidate for follow up studies.
Comment
Compound CID-2858522 at 10 uM inhibits TLK1 (30% POC) but not significantly inhibit other kinases that are involved in known NF-kappaB pathways.
Result Definitions
Show more
TIDNameDescriptionPID§Panel TargetsHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Outcome(ABL1(T315I))7v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
2%Inhibition(ABL1(T315I)) (10μM**)7Float%
3Outcome(ALK)20anaplastic lymphoma kinase Ki-1 [Homo sapiens]Outcome
4%Inhibition(ALK) (10μM**)20Float%
5Outcome(AURKA)25serine/threonine protein kinase 6 [Homo sapiens]Outcome
6%Inhibition(AURKA) (10μM**)25Float%
7Outcome(AURKB)26Aurora kinase B [Homo sapiens]Outcome
8%Inhibition(AURKB) (10μM**)26Float%
9Outcome(AURKC)27serine/threonine kinase 13 [Homo sapiens]Outcome
10%Inhibition(AURKC) (10μM**)27Float%
11Outcome(AXL)28AXL receptor tyrosine kinase isoform 2 [Homo sapiens]Outcome
12%Inhibition(AXL) (10μM**)28Float%
13Outcome(BMPR2)32bone morphogenetic protein receptor type II precursor [Homo sapiens]Outcome
14%Inhibition(BMPR2) (10μM**)32Float%
15Outcome(CDC2L1)49cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens]Outcome
16%Inhibition(CDC2L1) (10μM**)49Float%
17Outcome(CDC2L2)50cell division cycle 2-like 2 isoform 1 [Homo sapiens]Outcome
18%Inhibition(CDC2L2) (10μM**)50Float%
19Outcome(CDK11)51cell division cycle 2-like 6 (CDK8-like) [Homo sapiens]Outcome
20%Inhibition(CDK11) (10μM**)51Float%
21Outcome(CDK7)55cyclin-dependent kinase 7 [Homo sapiens]Outcome
22%Inhibition(CDK7) (10μM**)55Float%
23Outcome(CDK8)56cyclin-dependent kinase 8 [Homo sapiens]Outcome
24%Inhibition(CDK8) (10μM**)56Float%
25Outcome(CDK9)57cyclin-dependent kinase 9 [Homo sapiens]Outcome
26%Inhibition(CDK9) (10μM**)57Float%
27Outcome(CLK1)60clk1; putativeOutcome
28%Inhibition(CLK1) (10μM**)60Float%
29Outcome(CLK4)63CDC-like kinase 4 [Homo sapiens]Outcome
30%Inhibition(CLK4) (10μM**)63Float%
31Outcome(CSF1R)64colony stimulating factor 1 receptor precursor [Homo sapiens]Outcome
32%Inhibition(CSF1R) (10μM**)64Float%
33Outcome(DDR1)80discoidin domain receptor family, member 1 isoform b [Homo sapiens]Outcome
34%Inhibition(DDR1) (10μM**)80Float%
35Outcome(DDR2)81protein-tyrosine kinase [Homo sapiens]Outcome
36%Inhibition(DDR2) (10μM**)81Float%
37Outcome(EGFR(G719C))90epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
38%Inhibition(EGFR(G719C)) (10μM**)90Float%
39Outcome(EPHA3)97ephrin receptor EphA3 isoform a precursor [Homo sapiens]Outcome
40%Inhibition(EPHA3) (10μM**)97Float%
41Outcome(EPHA6)100EPH receptor A6 isoform a [Homo sapiens]Outcome
42%Inhibition(EPHA6) (10μM**)100Float%
43Outcome(EPHA7)101ephrin receptor EphA7 [Homo sapiens]Outcome
44%Inhibition(EPHA7) (10μM**)101Float%
45Outcome(EPHB3)105ephrin receptor EphB3 precursor [Homo sapiens]Outcome
46%Inhibition(EPHB3) (10μM**)105Float%
47Outcome(EPHB4)106ephrin receptor EphB4 precursor [Homo sapiens]Outcome
48%Inhibition(EPHB4) (10μM**)106Float%
49Outcome(ERK8)114mitogen-activated protein kinase 15 [Homo sapiens]Outcome
50%Inhibition(ERK8) (10μM**)114Float%
51Outcome(FLT1)123fms-related tyrosine kinase 1 [Homo sapiens]Outcome
52%Inhibition(FLT1) (10μM**)123Float%
53Outcome(FLT3)124fms-related tyrosine kinase 3 [Homo sapiens]Outcome
54%Inhibition(FLT3) (10μM**)124Float%
55Outcome(FLT3(D835H))125fms-related tyrosine kinase 3 [Homo sapiens]Outcome
56%Inhibition(FLT3(D835H)) (10μM**)125Float%
57Outcome(FLT3(D835Y))126fms-related tyrosine kinase 3 [Homo sapiens]Outcome
58%Inhibition(FLT3(D835Y)) (10μM**)126Float%
59Outcome(FLT3(ITD))127fms-related tyrosine kinase 3 [Homo sapiens]Outcome
60%Inhibition(FLT3(ITD)) (10μM**)127Float%
61Outcome(FLT3(N841I))128fms-related tyrosine kinase 3 [Homo sapiens]Outcome
62%Inhibition(FLT3(N841I)) (10μM**)128Float%
63Outcome(FLT4)129unnamed protein product [Homo sapiens]Outcome
64%Inhibition(FLT4) (10μM**)129Float%
65Outcome(FRK)130fyn-related kinase [Homo sapiens]Outcome
66%Inhibition(FRK) (10μM**)130Float%
67Outcome(INSRR)139insulin receptor-related receptor precursor [Homo sapiens]Outcome
68%Inhibition(INSRR) (10μM**)139Float%
69Outcome(JNK2)143mitogen-activated protein kinase 9 isoform JNK2 alpha1 [Homo sapiens]Outcome
70%Inhibition(JNK2) (10μM**)143Float%
71Outcome(KIT)145v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens]Outcome
72%Inhibition(KIT) (10μM**)145Float%
73Outcome(KIT(D816V))146v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens]Outcome
74%Inhibition(KIT(D816V)) (10μM**)146Float%
75Outcome(KIT(V559D))147v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog isoform 1 precursor [Homo sapiens]Outcome
76%Inhibition(KIT(V559D)) (10μM**)147Float%
77Outcome(LATS2)149LATS, large tumor suppressor, homolog 2 [Homo sapiens]Outcome
78%Inhibition(LATS2) (10μM**)149Float%
79Outcome(LIMK2)152LIM domain kinase 2 isoform 2a [Homo sapiens]Outcome
80%Inhibition(LIMK2) (10μM**)152Float%
81Outcome(LOK)154protein kinase [Homo sapiens]Outcome
82%Inhibition(LOK) (10μM**)154Float%
83Outcome(LTK)155leukocyte tyrosine kinase isoform 2 precursor [Homo sapiens]Outcome
84%Inhibition(LTK) (10μM**)155Float%
85Outcome(MAP4K1)159mitogen-activated protein kinase kinase kinase kinase 1 isoform 1 [Homo sapiens]Outcome
86%Inhibition(MAP4K1) (10μM**)159Float%
87Outcome(MAP4K3)160mitogen-activated protein kinase kinase kinase kinase 3 [Homo sapiens]Outcome
88%Inhibition(MAP4K3) (10μM**)160Float%
89Outcome(MAP4K5)162mitogen-activated protein kinase kinase kinase kinase 5 [Homo sapiens]Outcome
90%Inhibition(MAP4K5) (10μM**)162Float%
91Outcome(MERTK)174novel cellular proto-oncogeneOutcome
92%Inhibition(MERTK) (10μM**)174Float%
93Outcome(MET)175met proto-oncogene isoform b precursor [Homo sapiens]Outcome
94%Inhibition(MET) (10μM**)175Float%
95Outcome(MKNK1)176MAP kinase interacting serine/threonine kinase 1 [Homo sapiens]Outcome
96%Inhibition(MKNK1) (10μM**)176Float%
97Outcome(MKNK2)177map kinase-interacting kinase [Homo sapiens]Outcome
98%Inhibition(MKNK2) (10μM**)177Float%
99Outcome(MST1)184serine/threonine kinase 4 [Homo sapiens]Outcome
100%Inhibition(MST1) (10μM**)184Float%
101Outcome(MST2)185serine/threonine kinase 3 (STE20 homolog, yeast) [Homo sapiens]Outcome
102%Inhibition(MST2) (10μM**)185Float%
103Outcome(MUSK)188skeletal muscle receptor tyrosine kinase [Homo sapiens]Outcome
104%Inhibition(MUSK) (10μM**)188Float%
105Outcome(PDGFRA)213platelet-derived growth factor receptor alpha precursor [Homo sapiens]Outcome
106%Inhibition(PDGFRA) (10μM**)213Float%
107Outcome(PDGFRB)214platelet-derived growth factor receptor beta precursor [Homo sapiens]Outcome
108%Inhibition(PDGFRB) (10μM**)214Float%
109Outcome(PKAC-alpha)226cAMP-dependent protein kinase catalytic subunit alpha isoform 1 [Homo sapiens]Outcome
110%Inhibition(PKAC-alpha) (10μM**)226Float%
111Outcome(PLK3)232polo-like kinase 3 [Homo sapiens]Outcome
112%Inhibition(PLK3) (10μM**)232Float%
113Outcome(RET)249ret proto-oncogene isoform c [Homo sapiens]Outcome
114%Inhibition(RET) (10μM**)249Float%
115Outcome(RET(M918T))250ret proto-oncogene isoform c [Homo sapiens]Outcome
116%Inhibition(RET(M918T)) (10μM**)250Float%
117Outcome(RIPK1)253receptor (TNFRSF)-interacting serine-threonine kinase 1 [Homo sapiens]Outcome
118%Inhibition(RIPK1) (10μM**)253Float%
119Outcome(SLK)257serine/threonine kinase 2 [Homo sapiens]Outcome
120%Inhibition(SLK) (10μM**)257Float%
121Outcome(STK33)266serine/threonine kinase 33 [Homo sapiens]Outcome
122%Inhibition(STK33) (10μM**)266Float%
123Outcome(TIE1)273tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Homo sapiens]Outcome
124%Inhibition(TIE1) (10μM**)273Float%
125Outcome(TIE2)274TEK tyrosine kinase, endothelial precursor [Homo sapiens]Outcome
126%Inhibition(TIE2) (10μM**)274Float%
127Outcome(TRKA)281neurotrophic tyrosine kinase, receptor, type 1 isoform 1 [Homo sapiens]Outcome
128%Inhibition(TRKA) (10μM**)281Float%
129Outcome(TRKB)282neurotrophic tyrosine kinase, receptor, type 2 isoform a precursor [Homo sapiens]Outcome
130%Inhibition(TRKB) (10μM**)282Float%
131Outcome(TRKC)283TrkCOutcome
132%Inhibition(TRKC) (10μM**)283Float%
133Outcome(VEGFR2)288kinase insert domain receptor (a type III receptor tyrosine kinase) [Homo sapiens]Outcome
134%Inhibition(VEGFR2) (10μM**)288Float%
135Outcome(YANK2)290serine/threonine kinase 32B [Homo sapiens]Outcome
136%Inhibition(YANK2) (10μM**)290Float%
137Outcome(ABL1)2v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
138%Inhibition(ABL1) (10μM**)2Float%
139Outcome(BLK)30B lymphoid tyrosine kinase [Homo sapiens]Outcome
140%Inhibition(BLK) (10μM**)30Float%
141Outcome(BRAF)34v-raf murine sarcoma viral oncogene homolog B1 [Homo sapiens]Outcome
142%Inhibition(BRAF) (10μM**)34Float%
143Outcome(BRAF(V600E))35v-raf murine sarcoma viral oncogene homolog B1 [Homo sapiens]Outcome
144%Inhibition(BRAF(V600E)) (10μM**)35Float%
145Outcome(CIT)59citron [Homo sapiens]Outcome
146%Inhibition(CIT) (10μM**)59Float%
147Outcome(EGFR)88epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
148%Inhibition(EGFR) (10μM**)88Float%
149Outcome(EGFR(G719S))91epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
150%Inhibition(EGFR(G719S)) (10μM**)91Float%
151Outcome(EGFR(L861Q))93epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
152%Inhibition(EGFR(L861Q)) (10μM**)93Float%
153Outcome(FGFR1)117fibroblast growth factor receptor 1 isoform 3 precursor [Homo sapiens]Outcome
154%Inhibition(FGFR1) (10μM**)117Float%
155Outcome(FGFR4)121fibroblast growth factor receptor 4 isoform 2 precursor [Homo sapiens]Outcome
156%Inhibition(FGFR4) (10μM**)121Float%
157Outcome(FGR)122proto-oncogene tyrosine-protein kinase FGR [Homo sapiens]Outcome
158%Inhibition(FGR) (10μM**)122Float%
159Outcome(FYN)131protein-tyrosine kinase fyn isoform b [Homo sapiens]Outcome
160%Inhibition(FYN) (10μM**)131Float%
161Outcome(LCK)150lymphocyte-specific protein tyrosine kinase precursor [Homo sapiens]Outcome
162%Inhibition(LCK) (10μM**)150Float%
163Outcome(LYN)156Yamaguchi sarcoma viral (v-yes-1) oncogene homolog isoform A [Homo sapiens]Outcome
164%Inhibition(LYN) (10μM**)156Float%
165Outcome(PTK6)247PTK6 protein tyrosine kinase 6 [Homo sapiens]Outcome
166%Inhibition(PTK6) (10μM**)247Float%
167Outcome(RAF1)248v-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens]Outcome
168%Inhibition(RAF1) (10μM**)248Float%
169Outcome(TNNI3K)280TNNI3 interacting kinase isoform b [Homo sapiens]Outcome
170%Inhibition(TNNI3K) (10μM**)280Float%
171Outcome(ZAK)294MLK-related kinase isoform 2 [Homo sapiens]Outcome
172%Inhibition(ZAK) (10μM**)294Float%
173Outcome(ABL1(E255K))3v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
174%Inhibition(ABL1(E255K)) (10μM**)3Float%
175Outcome(ABL1(H396P))4v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
176%Inhibition(ABL1(H396P)) (10μM**)4Float%
177Outcome(ABL1(M351T))5v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
178%Inhibition(ABL1(M351T)) (10μM**)5Float%
179Outcome(ABL1(Q252H))6v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
180%Inhibition(ABL1(Q252H)) (10μM**)6Float%
181Outcome(ABL1(Y253F))8v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]Outcome
182%Inhibition(ABL1(Y253F)) (10μM**)8Float%
183Outcome(ABL2)9v-abl Abelson murine leukemia viral oncogene homolog 2 isoform a [Homo sapiens]Outcome
184%Inhibition(ABL2) (10μM**)9Float%
185Outcome(AMPK-alpha1)21AMP-activated protein kinase alpha-1 [Homo sapiens]Outcome
186%Inhibition(AMPK-alpha1) (10μM**)21Float%
187Outcome(ANKK1)23ankyrin repeat and kinase domain containing 1 [Homo sapiens]Outcome
188%Inhibition(ANKK1) (10μM**)23Float%
189Outcome(CAMK1)39calcium/calmodulin-dependent protein kinase I [Homo sapiens]Outcome
190%Inhibition(CAMK1) (10μM**)39Float%
191Outcome(CAMK4)46calcium/calmodulin-dependent protein kinase IV [Homo sapiens]Outcome
192%Inhibition(CAMK4) (10μM**)46Float%
193Outcome(CAMKK1)47calcium/calmodulin-dependent protein kinase 1 alpha isoform a [Homo sapiens]Outcome
194%Inhibition(CAMKK1) (10μM**)47Float%
195Outcome(CAMKK2)48calcium/calmodulin-dependent protein kinase kinase 2 beta isoform 1 [Homo sapiens]Outcome
196%Inhibition(CAMKK2) (10μM**)48Float%
197Outcome(CDK2)52cyclin-dependent kinase 2 isoform 1 [Homo sapiens]Outcome
198%Inhibition(CDK2) (10μM**)52Float%
199Outcome(CDK3)53cyclin-dependent kinase 3 [Homo sapiens]Outcome
200%Inhibition(CDK3) (10μM**)53Float%
201Outcome(CDK5)54cyclin-dependent kinase 5 [Homo sapiens]Outcome
202%Inhibition(CDK5) (10μM**)54Float%
203Outcome(CLK2)61CDC-like kinase 2 [Homo sapiens]Outcome
204%Inhibition(CLK2) (10μM**)61Float%
205Outcome(CSK)65c-src tyrosine kinase [Homo sapiens]Outcome
206%Inhibition(CSK) (10μM**)65Float%
207Outcome(CSNK1D)67casein kinase 1, delta isoform 2 [Homo sapiens]Outcome
208%Inhibition(CSNK1D) (10μM**)67Float%
209Outcome(CSNK1E)68casein kinase 1 epsilon [Homo sapiens]Outcome
210%Inhibition(CSNK1E) (10μM**)68Float%
211Outcome(CSNK1G2)70casein kinase 1, gamma 2 [Homo sapiens]Outcome
212%Inhibition(CSNK1G2) (10μM**)70Float%
213Outcome(CSNK1G3)71casein kinase 1, gamma 3 isoform 1 [Homo sapiens]Outcome
214%Inhibition(CSNK1G3) (10μM**)71Float%
215Outcome(DAPK3)76death-associated protein kinase 3 [Homo sapiens]Outcome
216%Inhibition(DAPK3) (10μM**)76Float%
217Outcome(DLK)82mitogen-activated protein kinase kinase kinase 12 [Homo sapiens]Outcome
218%Inhibition(DLK) (10μM**)82Float%
219Outcome(EGFR(E746-A750del))89epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
220%Inhibition(EGFR(E746-A750del)) (10μM**)89Float%
221Outcome(EGFR(L858R))92epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
222%Inhibition(EGFR(L858R)) (10μM**)92Float%
223Outcome(EPHA2)96ephrin receptor EphA2 [Homo sapiens]Outcome
224%Inhibition(EPHA2) (10μM**)96Float%
225Outcome(EPHA4)98ephrin receptor EphA4 [Homo sapiens]Outcome
226%Inhibition(EPHA4) (10μM**)98Float%
227Outcome(EPHA5)99ephrin receptor EphA5 isoform a [Homo sapiens]Outcome
228%Inhibition(EPHA5) (10μM**)99Float%
229Outcome(EPHA8)102EPH receptor A8 isoform 1 precursor [Homo sapiens]Outcome
230%Inhibition(EPHA8) (10μM**)102Float%
231Outcome(EPHB1)103ephrin receptor EphB1 precursor [Homo sapiens]Outcome
232%Inhibition(EPHB1) (10μM**)103Float%
233Outcome(EPHB2)104ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]Outcome
234%Inhibition(EPHB2) (10μM**)104Float%
235Outcome(FER)115fer (fps/fes related) tyrosine kinase [Homo sapiens]Outcome
236%Inhibition(FER) (10μM**)115Float%
237Outcome(FES)116V-FES feline sarcoma viral/V-FPS fujinami avian sarcoma viral oncogene homolog [Homo sapiens]Outcome
238%Inhibition(FES) (10μM**)116Float%
239Outcome(FGFR2)118fibroblast growth factor receptor 2 isoform 2 precursor [Homo sapiens]Outcome
240%Inhibition(FGFR2) (10μM**)118Float%
241Outcome(GAK)132cyclin G associated kinase [Homo sapiens]Outcome
242%Inhibition(GAK) (10μM**)132Float%
243Outcome(HCK)135hemopoietic cell kinase isoform p61HCK [Homo sapiens]Outcome
244%Inhibition(HCK) (10μM**)135Float%
245Outcome(ITK)141IL2-inducible T-cell kinase [Homo sapiens]Outcome
246%Inhibition(ITK) (10μM**)141Float%
247Outcome(JNK1)142mitogen-activated protein kinase 8 isoform JNK1 alpha1 [Homo sapiens]Outcome
248%Inhibition(JNK1) (10μM**)142Float%
249Outcome(JNK3)144mitogen-activated protein kinase 10 isoform 1 [Homo sapiens]Outcome
250%Inhibition(JNK3) (10μM**)144Float%
251Outcome(LATS1)148LATS homolog 1 [Homo sapiens]Outcome
252%Inhibition(LATS1) (10μM**)148Float%
253Outcome(MAP4K4)161mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens]Outcome
254%Inhibition(MAP4K4) (10μM**)161Float%
255Outcome(MELK)173maternal embryonic leucine zipper kinase [Homo sapiens]Outcome
256%Inhibition(MELK) (10μM**)173Float%
257Outcome(MYLK2)190skeletal myosin light chain kinase [Homo sapiens]Outcome
258%Inhibition(MYLK2) (10μM**)190Float%
259Outcome(MYO3A)191myosin IIIA [Homo sapiens]Outcome
260%Inhibition(MYO3A) (10μM**)191Float%
261Outcome(MYO3B)192myosin IIIB isoform 2 [Homo sapiens]Outcome
262%Inhibition(MYO3B) (10μM**)192Float%
263Outcome(NEK5)196NIMA (never in mitosis gene a)-related kinase 5 [Homo sapiens]Outcome
264%Inhibition(NEK5) (10μM**)196Float%
265Outcome(NLK)200nemo-like kinase [Homo sapiens]Outcome
266%Inhibition(NLK) (10μM**)200Float%
267Outcome(PCTK1)210PCTAIRE protein kinase 1 [Homo sapiens]Outcome
268%Inhibition(PCTK1) (10μM**)210Float%
269Outcome(PCTK2)211serine/threonine protein kinase [Homo sapiens]Outcome
270%Inhibition(PCTK2) (10μM**)211Float%
271Outcome(PCTK3)212PCTAIRE protein kinase 3 isoform b [Homo sapiens]Outcome
272%Inhibition(PCTK3) (10μM**)212Float%
273Outcome(PFTK1)216PFTAIRE protein kinase 1 [Homo sapiens]Outcome
274%Inhibition(PFTK1) (10μM**)216Float%
275Outcome(PKAC-beta)227cAMP-dependent protein kinase catalytic subunit beta isoform 2 [Homo sapiens]Outcome
276%Inhibition(PKAC-beta) (10μM**)227Float%
277Outcome(PRKCQ)237protein kinase C, theta [Homo sapiens]Outcome
278%Inhibition(PRKCQ) (10μM**)237Float%
279Outcome(PRKD1)238protein kinase D1 [Homo sapiens]Outcome
280%Inhibition(PRKD1) (10μM**)238Float%
281Outcome(PRKD2)239protein kinase D2 isoform A [Homo sapiens]Outcome
282%Inhibition(PRKD2) (10μM**)239Float%
283Outcome(PRKD3)240protein kinase D3 [Homo sapiens]Outcome
284%Inhibition(PRKD3) (10μM**)240Float%
285Outcome(PRKR)243eukaryotic translation initiation factor 2-alpha kinase 2 [Homo sapiens]Outcome
286%Inhibition(PRKR) (10μM**)243Float%
287Outcome(PTK2B)246PTK2B protein tyrosine kinase 2 beta isoform b [Homo sapiens]Outcome
288%Inhibition(PTK2B) (10μM**)246Float%
289Outcome(RIPK2)254receptor-interacting serine-threonine kinase 2 [Homo sapiens]Outcome
290%Inhibition(RIPK2) (10μM**)254Float%
291Outcome(ROS1)255proto-oncogene c-ros-1 protein precursor [Homo sapiens]Outcome
292%Inhibition(ROS1) (10μM**)255Float%
293Outcome(SNF1LK)259SNF1-like kinase [Homo sapiens]Outcome
294%Inhibition(SNF1LK) (10μM**)259Float%
295Outcome(SRC)261proto-oncogene tyrosine-protein kinase SRC [Homo sapiens]Outcome
296%Inhibition(SRC) (10μM**)261Float%
297Outcome(SRMS)262src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [Homo sapiens]Outcome
298%Inhibition(SRMS) (10μM**)262Float%
299Outcome(STK36)267serine/threonine kinase 36 [Homo sapiens]Outcome
300%Inhibition(STK36) (10μM**)267Float%
301Outcome(SYK)268spleen tyrosine kinase [Homo sapiens]Outcome
302%Inhibition(SYK) (10μM**)268Float%
303Outcome(TESK1)270testis-specific protein kinase 1 [Homo sapiens]Outcome
304%Inhibition(TESK1) (10μM**)270Float%
305Outcome(TGFBR2)272transforming growth factor, beta receptor II isoform B precursor [Homo sapiens]Outcome
306%Inhibition(TGFBR2) (10μM**)272Float%
307Outcome(TNIK)277TRAF2 and NCK interacting kinase [Homo sapiens]Outcome
308%Inhibition(TNIK) (10μM**)277Float%
309Outcome(TNK1)278TNK1 protein [Homo sapiens]Outcome
310%Inhibition(TNK1) (10μM**)278Float%
311Outcome(TTK)285TTK protein kinase [Homo sapiens]Outcome
312%Inhibition(TTK) (10μM**)285Float%
313Outcome(YES)292viral oncogene yes-1 homolog 1 [Homo sapiens]Outcome
314%Inhibition(YES) (10μM**)292Float%
315Outcome(YSK1)293serine/threonine kinase 25 [Homo sapiens]Outcome
316%Inhibition(YSK1) (10μM**)293Float%
317Outcome(p38-alpha)201mitogen-activated protein kinase 14 isoform 2 [Homo sapiens]Outcome
318%Inhibition(p38-alpha) (10μM**)201Float%
319Outcome(p38-beta)202mitogen-activated protein kinase 11 [Homo sapiens]Outcome
320%Inhibition(p38-beta) (10μM**)202Float%
321Outcome(p38-gamma)203p38gamma MAP Kinase [Homo sapiens]Outcome
322%Inhibition(p38-gamma) (10μM**)203Float%
323Outcome(EGFR(S752-I759del))94epidermal growth factor receptor isoform a precursor [Homo sapiens]Outcome
324%Inhibition(EGFR(S752-I759del)) (10μM**)94Float%
325Outcome(ERBB2)107erbB-2 isoform b [Homo sapiens]Outcome
326%Inhibition(ERBB2) (10μM**)107Float%
327Outcome(ERBB4)108v-erb-a erythroblastic leukemia viral oncogene homolog 4 isoform JM-a/CVT-2 precursor [Homo sapiens]Outcome
328%Inhibition(ERBB4) (10μM**)108Float%
329Outcome(MEK2)169mitogen-activated protein kinase kinase 2 [Homo sapiens]Outcome
330%Inhibition(MEK2) (10μM**)169Float%
331Outcome(PLK4)233Sak [Homo sapiens]Outcome
332%Inhibition(PLK4) (10μM**)233Float%
333Outcome(DMPK2)84CDC42 binding protein kinase gamma (DMPK-like) [Homo sapiens]Outcome
334%Inhibition(DMPK2) (10μM**)84Float%
335Outcome(EPHA1)95ephrin receptor EphA1 [Homo sapiens]Outcome
336%Inhibition(EPHA1) (10μM**)95Float%
337Outcome(MRCKA)182CDC42-binding protein kinase alpha isoform B [Homo sapiens]Outcome
338%Inhibition(MRCKA) (10μM**)182Float%
339Outcome(MRCKB)183CDC42-binding protein kinase beta [Homo sapiens]Outcome
340%Inhibition(MRCKB) (10μM**)183Float%
341Outcome(PTK2)245PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]Outcome
342%Inhibition(PTK2) (10μM**)245Float%
343Outcome(DCAMKL1)77doublecortin and CaM kinase-like 1 [Homo sapiens]Outcome
344%Inhibition(DCAMKL1) (10μM**)77Float%
345Outcome(DCAMKL2)78doublecortin and CaM kinase-like 2 isoform b [Homo sapiens]Outcome
346%Inhibition(DCAMKL2) (10μM**)78Float%
347Outcome(DCAMKL3)79PREDICTED: similar to doublecortin and CaM kinase-like 3 [Homo sapiens]Outcome
348%Inhibition(DCAMKL3) (10μM**)79Float%
349Outcome(DRAK1)85serine/threonine kinase 17a [Homo sapiens]Outcome
350%Inhibition(DRAK1) (10μM**)85Float%
351Outcome(DYRK1B)87dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B isoform a [Homo sapiens]Outcome
352%Inhibition(DYRK1B) (10μM**)87Float%
353Outcome(ERK3)111mitogen-activated protein kinase 6 [Homo sapiens]Outcome
354%Inhibition(ERK3) (10μM**)111Float%
355Outcome(ERK4)112mitogen-activated protein kinase 4 [Homo sapiens]Outcome
356%Inhibition(ERK4) (10μM**)112Float%
357Outcome(ERK5)113mitogen-activated protein kinase 7 isoform 1 [Homo sapiens]Outcome
358%Inhibition(ERK5) (10μM**)113Float%
359Outcome(GSK3A)133glycogen synthase kinase 3 alpha [Homo sapiens]Outcome
360%Inhibition(GSK3A) (10μM**)133Float%
361Outcome(GSK3B)134glycogen synthase kinase 3 beta [Homo sapiens]Outcome
362%Inhibition(GSK3B) (10μM**)134Float%
363Outcome(IRAK3)140interleukin-1 receptor-associated kinase 3 [Homo sapiens]Outcome
364%Inhibition(IRAK3) (10μM**)140Float%
365Outcome(MLCK)178myosin light chain kinase 3 [Homo sapiens]Outcome
366%Inhibition(MLCK) (10μM**)178Float%
367Outcome(PAK3)206p21-activated kinase 3 isoform a [Homo sapiens]Outcome
368%Inhibition(PAK3) (10μM**)206Float%
369Outcome(PHKG1)217phosphorylase kinase gamma subunit 1 [Homo sapiens]Outcome
370%Inhibition(PHKG1) (10μM**)217Float%
371Outcome(SNARK)258NUAK family, SNF1-like kinase, 2 [Homo sapiens]Outcome
372%Inhibition(SNARK) (10μM**)258Float%
373Outcome(AAK1)1AP2 associated kinase 1 [Homo sapiens]Outcome
374%Inhibition(AAK1) (10μM**)1Float%
375Outcome(AMPK-alpha2)22AMP-activated protein kinase alpha 2 catalytic subunit [Homo sapiens]Outcome
376%Inhibition(AMPK-alpha2) (10μM**)22Float%
377Outcome(ARK5)24AMPK-related protein kinase 5 [Homo sapiens]Outcome
378%Inhibition(ARK5) (10μM**)24Float%
379Outcome(BIKE)29BMP-2 inducible kinase isoform b [Homo sapiens]Outcome
380%Inhibition(BIKE) (10μM**)29Float%
381Outcome(CHEK1)58CHK1 checkpoint homolog [Homo sapiens]Outcome
382%Inhibition(CHEK1) (10μM**)58Float%
383Outcome(CSNK2A1)72casein kinase II alpha 1 subunit isoform a [Homo sapiens]Outcome
384%Inhibition(CSNK2A1) (10μM**)72Float%
385Outcome(CSNK2A2)73casein kinase 2, alpha prime polypeptide [Homo sapiens]Outcome
386%Inhibition(CSNK2A2) (10μM**)73Float%
387Outcome(DRAK2)86serine/threonine kinase 17b [Homo sapiens]Outcome
388%Inhibition(DRAK2) (10μM**)86Float%
389Outcome(FGFR3)119fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens]Outcome
390%Inhibition(FGFR3) (10μM**)119Float%
391Outcome(FGFR3(G697C))120fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens]Outcome
392%Inhibition(FGFR3(G697C)) (10μM**)120Float%
393Outcome(IKK-epsilon)137IKK-related kinase epsilon [Homo sapiens]Outcome
394%Inhibition(IKK-epsilon) (10μM**)137Float%
395Outcome(LKB1)153serine/threonine protein kinase 11 [Homo sapiens]Outcome
396%Inhibition(LKB1) (10μM**)153Float%
397Outcome(MAP3K4)157mitogen-activated protein kinase kinase kinase 4 isoform a [Homo sapiens]Outcome
398%Inhibition(MAP3K4) (10μM**)157Float%
399Outcome(MARK1)164MAP/microtubule affinity-regulating kinase 1 [Homo sapiens]Outcome
400%Inhibition(MARK1) (10μM**)164Float%
401Outcome(MARK2)165MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]Outcome
402%Inhibition(MARK2) (10μM**)165Float%
403Outcome(MARK3)166MAP/microtubule affinity-regulating kinase 3 isoform c [Homo sapiens]Outcome
404%Inhibition(MARK3) (10μM**)166Float%
405Outcome(MARK4)167MAP/microtubule affinity-regulating kinase 4 [Homo sapiens]Outcome
406%Inhibition(MARK4) (10μM**)167Float%
407Outcome(MEK1)168mitogen-activated protein kinase kinase 1 [Homo sapiens]Outcome
408%Inhibition(MEK1) (10μM**)168Float%
409Outcome(MLK1)179mitogen-activated protein kinase kinase kinase 9 [Homo sapiens]Outcome
410%Inhibition(MLK1) (10μM**)179Float%
411Outcome(MLK3)181mitogen-activated protein kinase kinase kinase 11 [Homo sapiens]Outcome
412%Inhibition(MLK3) (10μM**)181Float%
413Outcome(MST3)186serine/threonine kinase 24 isoform a [Homo sapiens]Outcome
414%Inhibition(MST3) (10μM**)186Float%
415Outcome(MST4)187serine/threonine protein kinase MST4 isoform 1 [Homo sapiens]Outcome
416%Inhibition(MST4) (10μM**)187Float%
417Outcome(MYLK)189myosin light chain kinase isoform 2 [Homo sapiens]Outcome
418%Inhibition(MYLK) (10μM**)189Float%
419Outcome(NEK2)195NIMA (never in mitosis gene a)-related kinase 2 [Homo sapiens]Outcome
420%Inhibition(NEK2) (10μM**)195Float%
421Outcome(NEK6)197putative serine-threonine protein kinase [Homo sapiens]Outcome
422%Inhibition(NEK6) (10μM**)197Float%
423Outcome(NEK7)198NIMA (never in mitosis gene a)-related kinase 7 [Homo sapiens]Outcome
424%Inhibition(NEK7) (10μM**)198Float%
425Outcome(NEK9)199NIMA related kinase 9 [Homo sapiens]Outcome
426%Inhibition(NEK9) (10μM**)199Float%
427Outcome(PHKG2)218phosphorylase kinase, gamma 2 (testis) [Homo sapiens]Outcome
428%Inhibition(PHKG2) (10μM**)218Float%
429Outcome(PIP5K1A)22468 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [Homo sapiens]Outcome
430%Inhibition(PIP5K1A) (10μM**)224Float%
431Outcome(PIP5K2B)225phosphatidylinositol-5-phosphate 4-kinase, type II, beta [Homo sapiens]Outcome
432%Inhibition(PIP5K2B) (10μM**)225Float%
433Outcome(PKN1)229protein kinase N1 isoform 1 [Homo sapiens]Outcome
434%Inhibition(PKN1) (10μM**)229Float%
435Outcome(PKN2)230protein kinase N2 [Homo sapiens]Outcome
436%Inhibition(PKN2) (10μM**)230Float%
437Outcome(RIOK1)251RIO kinase 1 isoform 1 [Homo sapiens]Outcome
438%Inhibition(RIOK1) (10μM**)251Float%
439Outcome(RIOK3)252sudD suppressor of bimD6 homolog [Homo sapiens]Outcome
440%Inhibition(RIOK3) (10μM**)252Float%
441Outcome(SNF1LK2)260SNF1-like kinase 2 [Homo sapiens]Outcome
442%Inhibition(SNF1LK2) (10μM**)260Float%
443Outcome(SRPK1)263SFRS protein kinase 1 [Homo sapiens]Outcome
444%Inhibition(SRPK1) (10μM**)263Float%
445Outcome(SRPK2)264serine kinase SRPK2 [Homo sapiens]Outcome
446%Inhibition(SRPK2) (10μM**)264Float%
447Outcome(SgK085)256myosin light chain kinase family, member 4 [Homo sapiens]Outcome
448%Inhibition(SgK085) (101μM**)256Float%
449Outcome(TLK2)276tousled-like kinase 2 [Homo sapiens]Outcome
450%Inhibition(TLK2) (10μM**)276Float%
451Outcome(TYRO3)287TYRO3 protein tyrosine kinase [Homo sapiens]Outcome
452%Inhibition(TYRO3) (10μM**)287Float%
453Outcome(WEE1)289wee1 tyrosine kinase [Homo sapiens]Outcome
454%Inhibition(WEE1) (10μM**)289Float%
455Outcome(ACVR1)10activin A type I receptor precursor [Homo sapiens]Outcome
456%Inhibition(ACVR1) (10μM**)10Float%
457Outcome(ADCK3)15chaperone, ABC1 activity of bc1 complex like precursor [Homo sapiens]Outcome
458%Inhibition(ADCK3) (10μM**)15Float%
459Outcome(ADCK4)16aarF domain containing kinase 4 [Homo sapiens]Outcome
460%Inhibition(ADCK4) (10μM**)16Float%
461Outcome(BMX)33BMX non-receptor tyrosine kinase [Homo sapiens]Outcome
462%Inhibition(BMX) (10μM**)33Float%
463Outcome(BTK)38Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]Outcome
464%Inhibition(BTK) (10μM**)38Float%
465Outcome(TEC)269tec protein tyrosine kinase [Homo sapiens]Outcome
466%Inhibition(TEC) (10μM**)269Float%
467Outcome(TGFBR1)271transforming growth factor, beta receptor I isoform 1 precursor [Homo sapiens]Outcome
468%Inhibition(TGFBR1) (10μM**)271Float%
469Outcome(TXK)286TXK tyrosine kinase [Homo sapiens]Outcome
470%Inhibition(TXK) (10μM**)286Float%
471Outcome(ACVR1B)11activin A type IB receptor isoform a precursor [Homo sapiens]Outcome
472%Inhibition(ACVR1B) (10μM**)11Float%
473Outcome(ACVR2A)12activin A receptor, type IIA precursor [Homo sapiens]Outcome
474%Inhibition(ACVR2A) (10μM**)12Float%
475Outcome(ACVR2B)13activin A type IIB receptor precursor [Homo sapiens]Outcome
476%Inhibition(ACVR2B) (10μM**)13Float%
477Outcome(ACVRL1)14activin A receptor type II-like 1 [Homo sapiens]Outcome
478%Inhibition(ACVRL1) (10μM**)14Float%
479Outcome(DMPK)83myotonic dystrophy protein kinase isoform 2 [Homo sapiens]Outcome
480%Inhibition(DMPK) (10μM**)83Float%
481Outcome(LIMK1)151LIM domain kinase 1 [Homo sapiens]Outcome
482%Inhibition(LIMK1) (10μM**)151Float%
483Outcome(PKMYT1)228protein kinase Myt1 isoform 2 [Homo sapiens]Outcome
484%Inhibition(PKMYT1) (10μM**)228Float%
485Outcome(TNK2)279tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]Outcome
486%Inhibition(TNK2) (10μM**)279Float%
487Outcome(CAMK1D)40calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens]Outcome
488%Inhibition(CAMK1D) (10μM**)40Float%
489Outcome(CLK3)62CDC-like kinase 3 isoform b [Homo sapiens]Outcome
490%Inhibition(CLK3) (10μM**)62Float%
491Outcome(CSNK1A1L)66casein kinase 1, alpha 1-like [Homo sapiens]Outcome
492%Inhibition(CSNK1A1L) (10μM**)66Float%
493Outcome(NEK1)194NIMA (never in mitosis gene a)-related kinase 1 [Homo sapiens]Outcome
494%Inhibition(NEK1) (10μM**)194Float%
495Outcome(PAK1)204p21-activated kinase 1 isoform 2 [Homo sapiens]Outcome
496%Inhibition(PAK1) (10μM**)204Float%
497Outcome(PRKCD)234protein kinase C, delta [Homo sapiens]Outcome
498%Inhibition(PRKCD) (10μM**)234Float%
499Outcome(CAMK2A)42calcium/calmodulin-dependent protein kinase IIA isoform 2 [Homo sapiens]Outcome
500%Inhibition(CAMK2A) (10μM**)42Float%
501Outcome(MLK2)180mitogen-activated protein kinase kinase kinase 10 [Homo sapiens]Outcome
502%Inhibition(MLK2) (10μM**)180Float%
503Outcome(PIM1)221pim-1 oncogene [Homo sapiens]Outcome
504%Inhibition(PIM1) (10μM**)221Float%
505Outcome(PIM2)222pim-2 oncogene [Homo sapiens]Outcome
506%Inhibition(PIM2) (10μM**)222Float%
507Outcome(PIM3)223pim-3 oncogene [Homo sapiens]Outcome
508%Inhibition(PIM3) (10μM**)223Float%
509Outcome(PRKCE)235protein kinase C, epsilon [Homo sapiens]Outcome
510%Inhibition(PRKCE) (10μM**)235Float%
511Outcome(PRKCH)236protein kinase C, eta [Homo sapiens]Outcome
512%Inhibition(PRKCH) (10μM**)236Float%
513Outcome(CAMK1G)41calcium/calmodulin-dependent protein kinase IG [Homo sapiens]Outcome
514%Inhibition(CAMK1G) (10μM**)41Float%
515Outcome(MEK4)171mitogen-activated protein kinase kinase 4 [Homo sapiens]Outcome
516%Inhibition(MEK4) (10μM**)171Float%
517Outcome(MEK6)172mitogen-activated protein kinase kinase 6 [Homo sapiens]Outcome
518%Inhibition(MEK6) (10μM**)172Float%
519Outcome(STK16)265PKL12 protein [Homo sapiens]Outcome
520%Inhibition(STK16) (10μM**)265Float%
521Outcome(BRSK1)36BR serine/threonine kinase 1 [Homo sapiens]Outcome
522%Inhibition(BRSK1) (10μM**)36Float%
523Outcome(BRSK2)37BR serine/threonine kinase 2 [Homo sapiens]Outcome
524%Inhibition(BRSK2) (10μM**)37Float%
525Outcome(CSNK1G1)69casein kinase 1, gamma 1 [Homo sapiens]Outcome
526%Inhibition(CSNK1G1) (10μM**)69Float%
527Outcome(MEK3)170mitogen-activated protein kinase kinase 3 isoform A [Homo sapiens]Outcome
528%Inhibition(MEK3) (10μM**)170Float%
529Outcome(PAK4)207p21-activated kinase 4 isoform 3 [Homo sapiens]Outcome
530%Inhibition(PAK4) (10μM**)207Float%
531Outcome(PAK6)208p21-activated kinase 6 [Homo sapiens]Outcome
532%Inhibition(PAK6) (10μM**)208Float%
533Outcome(PAK7/PAK5)209p21-activated kinase 7 [Homo sapiens]Outcome
534%Inhibition(PAK7/PAK5) (10μM**)209Float%
535Outcome(PDPK1)2153-phosphoinositide dependent protein kinase-1 isoform 1 [Homo sapiens]Outcome
536%Inhibition(PDPK1) (10μM**)215Float%
537Outcome(PLK1)231polo-like kinase [Homo sapiens]Outcome
538%Inhibition(PLK1) (10μM**)231Float%
539Outcome(TLK1)275tousled-like kinase 1 [Homo sapiens]Outcome
540%Inhibition(TLK1) (10μM**)275Float%
541Outcome(AKT3)19v-akt murine thymoma viral oncogene homolog 3 isoform 1 [Homo sapiens]Outcome
542%Inhibition(AKT3) (10μM**)19Float%
543Outcome(CAMK2D)44multifunctional calcium/calmodulin-dependent protein kinase II delta2 isoform [Homo sapiens]Outcome
544%Inhibition(CAMK2D) (10μM**)44Float%
545Outcome(CAMK2G)45calcium/calmodulin-dependent protein kinase II gamma isoform 6 [Homo sapiens]Outcome
546%Inhibition(CAMK2G) (10μM**)45Float%
547Outcome(DAPK1)74death-associated protein kinase 1 [Homo sapiens]Outcome
548%Inhibition(DAPK1) (10μM**)74Float%
549Outcome(PRKG2)242protein kinase, cGMP-dependent, type II [Homo sapiens]Outcome
550%Inhibition(PRKG2) (10μM**)242Float%
551Outcome(DAPK2)75death-associated protein kinase 2 [Homo sapiens]Outcome
552%Inhibition(DAPK2) (10μM**)75Float%
553Outcome(PIK3CA)219phosphoinositide-3-kinase, catalytic, alpha polypeptide [Homo sapiens]Outcome
554%Inhibition(PIK3CA) (10μM**)219Float%
555Outcome(PIK3CA(E545K))220phosphoinositide-3-kinase, catalytic, alpha polypeptide [Homo sapiens]Outcome
556%Inhibition(PIK3CA(E545K)) (10μM**)220Float%
557Outcome(AKT1)17v-akt murine thymoma viral oncogene homolog 1 [Homo sapiens]Outcome
558%Inhibition(AKT1) (10μM**)17Float%
559Outcome(AKT2)18v-akt murine thymoma viral oncogene homolog 2 [Homo sapiens]Outcome
560%Inhibition(AKT2) (10μM**)18Float%
561Outcome(CAMK2B)43calcium/calmodulin-dependent protein kinase IIB isoform 1 [Homo sapiens]Outcome
562%Inhibition(CAMK2B) (10μM**)43Float%
563Outcome(PAK2)205p21-activated kinase 2 [Homo sapiens]Outcome
564%Inhibition(PAK2) (10μM**)205Float%
565Outcome(PRKG1)241protein kinase, cGMP-dependent, type I isoform 2 [Homo sapiens]Outcome
566%Inhibition(PRKG1) (10μM**)241Float%
567Outcome(PRKX)244protein kinase, X-linked [Homo sapiens]Outcome
568%Inhibition(PRKX) (10μM**)244Float%
569Outcome(TSSK1)284testis-specific serine kinase 1 [Homo sapiens]Outcome
570%Inhibition(TSSK1) (10μM**)284Float%
571Outcome(ZAP70)295zeta-chain associated protein kinase 70kDa isoform 2 [Homo sapiens]Outcome
572%Inhibition(ZAP70) (10μM**)295Float%
573Outcome(INSR)138insulin receptor isoform Long precursor [Homo sapiens]Outcome
574%Inhibition(INSR) (10μM**)138Float%
575Outcome(NDR2)193serine/threonine kinase 38 like [Homo sapiens]Outcome
576%Inhibition(NDR2) (10μM**)193Float%
577Outcome(BMPR1A)31bone morphogenetic protein receptor, type IA precursor [Homo sapiens]Outcome
578%Inhibition(BMPR1A) (10μM**)31Float%
579Outcome(ERK1)109mitogen-activated protein kinase 3 isoform 1 [Homo sapiens]Outcome
580%Inhibition(ERK1) (10μM**)109Float%
581Outcome(ERK2)110mitogen-activated protein kinase 1 [Homo sapiens]Outcome
582%Inhibition(ERK2) (10μM**)110Float%
583Outcome(IGF1R)136insulin-like growth factor 1 receptor precursor [Homo sapiens]Outcome
584%Inhibition(IGF1R) (10μM**)136Float%
585Outcome(MAP3K5)158mitogen-activated protein kinase kinase kinase 5 [Homo sapiens]Outcome
586%Inhibition(MAP3K5) (10μM**)158Float%
587Outcome(MAPKAPK2)163mitogen-activated protein kinase-activated protein kinase 2 isoform 2 [Homo sapiens]Outcome
588%Inhibition(MAPKAPK2) (10μM**)163Float%
589Outcome(YANK3)291serine/threonine kinase 32C [Homo sapiens]Outcome
590%Inhibition(YANK3) (10μM**)291Float%
591Outcome(ABL1(F317I))296c-abl oncogene 1, receptor tyrosine kinaseOutcome
592%Inhibition(ABL1(F317I)) (10μM**)296Float%
593Outcome(ABL1(F317L))297c-abl oncogene 1, receptor tyrosine kinaseOutcome
594%Inhibition(ABL1(F317L)) (10μM**)297Float%
595Outcome(BMPR1B)298bone morphogenetic protein receptor, type IBOutcome
596%Inhibition(BMPR1B) (10μM**)298Float%
597Outcome(CDKL2)299cyclin-dependent kinase-like 2 (CDC2-related kinase)Outcome
598%Inhibition(CDKL2) (10μM**)299Float%
599Outcome(CHEK2)300CHK2 checkpoint homolog (S. pombe)Outcome
600%Inhibition(CHEK2) (10μM**)300Float%
601Outcome(EGFR(L747-E749del, A750P))301epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Outcome
602%Inhibition(EGFR(L747-E749del, A750P)) (10μM**)301Float%
603Outcome(EGFR(L747-S752del, P753S))302epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Outcome
604%Inhibition(EGFR(L747-S752del, P753S)) (10μM**)302Float%
605Outcome(EGFR(L747-T751del,Sins))303epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Outcome
606%Inhibition(EGFR(L747-T751del,Sins)) (10μM**)303Float%
607Outcome(FLT3(K663Q))304fms-related tyrosine kinase 3Outcome
608%Inhibition(FLT3(K663Q)) (10μM**)304Float%
609Outcome(GCN2(Kin.Dom.2,S808G))305eukaryotic translation initiation factor 2 alpha kinase 4Outcome
610%Inhibition(GCN2(Kin.Dom.2,S808G)) (10μM**)305Float%
611Outcome(HIPK1)306homeodomain interacting protein kinase 1Outcome
612%Inhibition(HIPK1) (10μM**)306Float%
613Outcome(IKK-alpha)307conserved helix-loop-helix ubiquitous kinaseOutcome
614%Inhibition(IKK-alpha) (10μM**)307Float%
615Outcome(IKK-beta)308inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaOutcome
616%Inhibition(IKK-beta) (10μM**)308Float%
617Outcome(JAK1(Kin.Dom.1))309Janus kinase 1Outcome
618%Inhibition(JAK1(Kin.Dom.1)) (10μM**)309Float%
619Outcome(JAK1(Kin.Dom.2))310Janus kinase 1Outcome
620%Inhibition(JAK1(Kin.Dom.2)) (10μM**)310Float%
621Outcome(JAK2(Kin.Dom.2))311Janus kinase 2Outcome
622%Inhibition(JAK2(Kin.Dom.2)) (10μM**)311Float%
623Outcome(JAK3(Kin.Dom.2))312Janus kinase 3Outcome
624%Inhibition(JAK3(Kin.Dom.2)) (10μM**)312Float%
625Outcome(KIT(V559D,T670I))313v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologOutcome
626%Inhibition(KIT(V559D,T670I)) (10μM**)313Float%
627Outcome(KIT(V559D,V654A))314v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologOutcome
628%Inhibition(KIT(V559D,V654A)) (10μM**)314Float%
629Outcome(MAP3K3)315mitogen-activated protein kinase kinase kinase 3Outcome
630%Inhibition(MAP3K3) (10μM**)315Float%
631Outcome(MAP4K2)316mitogen-activated protein kinase kinase kinase kinase 2Outcome
632%Inhibition(MAP4K2) (10μM**)316Float%
633Outcome(MAPKAPK5)317mitogen-activated protein kinase-activated protein kinase 5Outcome
634%Inhibition(MAPKAPK5) (10μM**)317Float%
635Outcome(MINK)318misshapen-like kinase 1 (zebrafish)Outcome
636%Inhibition(MINK) (10μM**)318Float%
637Outcome(MST1R)319macrophage stimulating 1 receptor (c-met-related tyrosine kinase)Outcome
638%Inhibition(MST1R) (10μM**)319Float%
639Outcome(p38-delta)320mitogen-activated protein kinase 13Outcome
640%Inhibition(p38-delta) (10μM**)320Float%
641Outcome(PFTAIRE2)321PFTAIRE protein kinase 2Outcome
642%Inhibition(PFTAIRE2) (10μM**)321Float%
643Outcome(PIK3C2B)322phosphoinositide-3-kinase, class 2, beta polypeptideOutcome
644%Inhibition(PIK3C2B) (10μM**)322Float%
645Outcome(PIK3CB)323phosphoinositide-3-kinase, catalytic, beta polypeptideOutcome
646%Inhibition(PIK3CB) (10μM**)323Float%
647Outcome(PIK3CD)324phosphoinositide-3-kinase, catalytic, delta polypeptideOutcome
648%Inhibition(PIK3CD) (10μM**)324Float%
649Outcome(PIK3CG)325phosphoinositide-3-kinase, catalytic, gamma polypeptideOutcome
650%Inhibition(PIK3CG) (10μM**)325Float%
651Outcome(RET(V804L))326ret proto-oncogeneOutcome
652%Inhibition(RET(V804L)) (10μM**)326Float%
653Outcome(RET(V804M))327ret proto-oncogeneOutcome
654%Inhibition(RET(V804M)) (10μM**)327Float%
655Outcome(RIOK2)328RIO kinase 2 (yeast)Outcome
656%Inhibition(RIOK2) (10μM**)328Float%
657Outcome(RIPK4)329receptor-interacting serine-threonine kinase 4Outcome
658%Inhibition(RIPK4) (10μM**)329Float%
659Outcome(ROCK2)330Rho-associated, coiled-coil containing protein kinase 2Outcome
660%Inhibition(ROCK2) (10μM**)330Float%
661Outcome(RPS6KA1(Kin.Dom.1))331ribosomal protein S6 kinase, 90kDa, polypeptide 1Outcome
662%Inhibition(RPS6KA1(Kin.Dom.1)) (10μM**)331Float%
663Outcome(RPS6KA1(Kin.Dom.2))332ribosomal protein S6 kinase, 90kDa, polypeptide 1Outcome
664%Inhibition(RPS6KA1(Kin.Dom.2)) (10μM**)332Float%
665Outcome(RPS6KA2(Kin.Dom.1))333ribosomal protein S6 kinase, 90kDa, polypeptide 2Outcome
666%Inhibition(RPS6KA2(Kin.Dom.1)) (10μM**)333Float%
667Outcome(RPS6KA2(Kin.Dom.2))334ribosomal protein S6 kinase, 90kDa, polypeptide 2Outcome
668%Inhibition(RPS6KA2(Kin.Dom.2)) (10μM**)334Float%
669Outcome(RPS6KA3(Kin.Dom.1))335ribosomal protein S6 kinase, 90kDa, polypeptide 3Outcome
670%Inhibition(RPS6KA3(Kin.Dom.1)) (10μM**)335Float%
671Outcome(RPS6KA4(Kin.Dom.1))336ribosomal protein S6 kinase, 90kDa, polypeptide 4Outcome
672%Inhibition(RPS6KA4(Kin.Dom.1)) (10μM**)336Float%
673Outcome(RPS6KA4(Kin.Dom.2))337ribosomal protein S6 kinase, 90kDa, polypeptide 4Outcome
674%Inhibition(RPS6KA4(Kin.Dom.2)) (10μM**)337Float%
675Outcome(RPS6KA5(Kin.Dom.1))338ribosomal protein S6 kinase, 90kDa, polypeptide 5Outcome
676%Inhibition(RPS6KA5(Kin.Dom.1)) (10μM**)338Float%
677Outcome(RPS6KA5(Kin.Dom.2))339ribosomal protein S6 kinase, 90kDa, polypeptide 5Outcome
678%Inhibition(RPS6KA5(Kin.Dom.2)) (10μM**)339Float%
679Outcome(RPS6KA6(Kin.Dom.1))340ribosomal protein S6 kinase, 90kDa, polypeptide 6Outcome
680%Inhibition(RPS6KA6(Kin.Dom.1)) (10μM**)340Float%
681Outcome(RPS6KA6(Kin.Dom.2))341ribosomal protein S6 kinase, 90kDa, polypeptide 6Outcome
682%Inhibition(RPS6KA6(Kin.Dom.2)) (10μM**)341Float%
683Outcome(SgK110)342similar to Putative uncharacterized serine/threonine-protein kinase SgK110Outcome
684%Inhibition(SgK110) (10μM**)342Float%
685Outcome(SRPK3)343SFRS protein kinase 3Outcome
686%Inhibition(SRPK3) (10μM**)343Float%
687Outcome(STK35)344serine/threonine kinase 35Outcome
688%Inhibition(STK35) (10μM**)344Float%
689Outcome(TAK1)345mitogen-activated protein kinase kinase kinase 7Outcome
690%Inhibition(TAK1) (10μM**)345Float%
691Outcome(TAOK1)346TAO kinase 1Outcome
692%Inhibition(TAOK1) (10μM**)346Float%
693Outcome(TAOK3)347TAO kinase 3Outcome
694%Inhibition(TAOK3) (10μM**)347Float%
695Outcome(TYK2(Kin.Dom.1))348tyrosine kinase 2Outcome
696%Inhibition(TYK2(Kin.Dom.1)) (10μM**)348Float%
697Outcome(TYK2(Kin.Dom.2))349tyrosine kinase 2Outcome
698%Inhibition(TYK2(Kin.Dom.2)) (10μM**)349Float%
699Outcome(ULK1)350unc-51-like kinase 1 (C. elegans)Outcome
700%Inhibition(ULK1) (10μM**)350Float%
701Outcome(ULK2)351unc-51-like kinase 2 (C. elegans)Outcome
702%Inhibition(ULK2) (10μM**)351Float%
703Outcome(ULK3)352unc-51-like kinase 3 (C. elegans)Outcome
704%Inhibition(ULK3) (10μM**)352Float%
705Outcome(WEE2)353WEE1 homolog 2 (S. pombe)Outcome
706%Inhibition(WEE2) (10μM**)353Float%

** Test Concentration. § Panel component ID.
Additional Information
Grant Number: X01 MH077633-01

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