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BioAssay: AID 162309

Compound was evaluated for inhibition of Prostaglandin G/H synthase 1

Compound was evaluated for inhibition of Prostaglandin G/H synthase 1 ..more
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 Tested Compounds
 Tested Compounds
All(6)
 
 
Active(6)
 
 
 Tested Substances
 Tested Substances
All(6)
 
 
Active(6)
 
 
 Related BioAssays
 Related BioAssays
AID: 162309
Data Source: ChEMBL (159569)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2014-08-23

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compounds: 6
Description:
Compound was evaluated for inhibition of Prostaglandin G/H synthase 1
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
Putative Target:
ChEMBL Target ID: 96
Target Type: SINGLE PROTEIN
Pref Name: Cyclooxygenase-1
Synonyms: COX-1;Cyclooxygenase-1;PGH synthase 1;PGHS-1;PHS 1;Prostaglandin G/H synthase 1;Prostaglandin H2 synthase 1;Prostaglandin-endoperoxide synthase 1;
Gene Name: COX1;PTGS1;
Protein Accession: P23219;
Protein GI: 317373262;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: enzyme reductase
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1996
Volume: 6
Issue: 6
First Page: 707
Last Page: 712
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Binding
Assay Data Source: Scientific Literature
Result Definitions
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TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1IC50*IC50 PubChem standard valueFloatμM
3BEIBinding Efficiency Index(nM)Float
2SEISurface Efficiency Index(nM)Float
4LELigand EfficiencyFloat
5LLELipophilic Ligand EfficiencyFloat
6IC50 activity commentIC50 activity commentString
7IC50 standard flagIC50 standard flagInteger
8IC50 qualifierIC50 qualifierString
9IC50 published valueIC50 published valueFloatμM
10IC50 standard valueIC50 standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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