Bookmark and Share
BioAssay: AID 150470

Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytes

Title: Purine and pyrimidine (P2) receptors as drug targets.
..more
_
   
 Tested Compounds
 Tested Compounds
All(17)
 
 
Active(15)
 
 
Unspecified(2)
 
 
 Tested Substances
 Tested Substances
All(17)
 
 
Active(15)
 
 
Unspecified(2)
 
 
AID: 150470
Data Source: ChEMBL (147717)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-24
Modify Date: 2014-12-06

Data Table ( Complete ):           View Active Data    View All Data
Target
Sequence: RecName: Full=P2Y purinoceptor 1; Short=P2Y1; AltName: Full=6H1 orphan receptor; AltName: Full=ATP receptor; AltName: Full=Purinergic receptor
Description ..   
Comment ..   

Gene:P2RY1     Conserved Domain     Related Protein 3D Structures     More BioActivity Data..
BioActive Compounds: 15
Description:
Title: Purine and pyrimidine (P2) receptors as drug targets.
(PMID: 12213051)
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Functional
Target Type: Target is a single protein chain
Assay Data Source: Scientific Literature
Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1EC50*EC50 PubChem standard valueFloatμM
2EC50 activity commentEC50 activity commentString
3EC50 standard flagEC50 standard flagInteger
4EC50 qualifierEC50 qualifierString
5EC50 published valueEC50 published valueFloatnM
6EC50 standard valueEC50 standard valueFloatnM
7EC50 binding domainsEC50 binding domainsString

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
PageFrom: