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BioAssay: AID 150170

Antagonist activity against recombinant rat P2X purinoceptor 5 (P2X5)

Title: Purine and pyrimidine (P2) receptors as drug targets.
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 Tested Compounds
 Tested Compounds
All(7)
 
 
Active(6)
 
 
Unspecified(1)
 
 
 Tested Substances
 Tested Substances
All(7)
 
 
Active(6)
 
 
Unspecified(1)
 
 
 Related BioAssays
 Related BioAssays
AID: 150170
Data Source: ChEMBL (147417)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-24
Modify Date: 2014-05-20

Data Table ( Complete ):           Active    All
BioActive Compounds: 6
Description:
Title: Purine and pyrimidine (P2) receptors as drug targets.
(PMID: 12213051)
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 10538
Target Type: SINGLE PROTEIN
Pref Name: P2X purinoceptor 5
Synonyms: ATP receptor;P2X purinoceptor 5;P2X5;Purinergic receptor;
Gene Name: P2rx5;
Protein Accession: P51578;
Protein GI: 1709522;
Organism: Rattus norvegicus
Tax ID: 10116
Target Classification: ion channel lgic p2x
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
Categorized Comment
Assay Type: Functional

Assay Data Source: Scientific Literature

Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1EC50*EC50 PubChem standard valueFloatμM
2EC50 activity commentEC50 activity commentString
3EC50 standard flagEC50 standard flagInteger
4EC50 qualifierEC50 qualifierString
5EC50 published valueEC50 published valueFloatnM
6EC50 standard valueEC50 standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
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