Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 30 uM, expressed in Xenopus oocytes
Title: Purine and pyrimidine (P2) receptors as drug targets.
BioActive Compounds: 5
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
ChEMBL Target ID: 11949
Target Type: SINGLE PROTEIN
Pref Name: P2X purinoceptor 4
Synonyms: ATP receptor;P2X purinoceptor 4;P2X4;Purinergic receptor;
Gene Name: P2rx4;
Protein Accession: P51577;
Protein GI: 1709521;
Organism: Rattus norvegicus
Tax ID: 10116
Target Classification: ion channel lgic p2x
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Functional
Assay Data Source: Scientific Literature
BAO: Assay Format: cell-based format
Assay Cell Type: Oocytes
* Activity Concentration.
Data Table (Concise)