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BioAssay: AID 146135

Tested for the inhibition of human neuronal tissue Neuronal nitric oxide synthase

Tested for the inhibition of human neuronal tissue Neuronal nitric oxide synthase ..more
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 Tested Compounds
 Tested Compounds
All(1)
 
 
Active(1)
 
 
 Tested Substances
 Tested Substances
All(1)
 
 
Active(1)
 
 
 Related BioAssays
 Related BioAssays
AID: 146135
Data Source: ChEMBL (143379)
BioAssay Type: Confirmatory, Concentration-Response Relationship Observed
Depositor Category: Literature, Extracted
BioAssay Version:
Deposit Date: 2010-05-20
Modify Date: 2014-08-23

Data Table ( Complete ):           View Active Data    View All Data
BioActive Compound: 1
Description:
Tested for the inhibition of human neuronal tissue Neuronal nitric oxide synthase
Comment
Compounds with activity <= 50uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Putative Target:

ChEMBL Target ID: 11037
Target Type: SINGLE PROTEIN
Pref Name: Nitric-oxide synthase, brain
Synonyms: bNOS;Constitutive NOS;N-NOS;NC-NOS;Neuronal NOS;Nitric oxide synthase; brain;nNOS;NOS type I;Peptidyl-cysteine S-nitrosylase NOS1;
Gene Name: NOS1;
Protein Accession: P29475;
Protein GI: 1709333;
Organism: Homo sapiens
Tax ID: 9606
Target Classification: enzyme
Confidence: Homologous single protein target assigned
Relationship Type: Homologous protein target assigned


Publication:
Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 13
First Page: 1763
Last Page: 1768
Categorized Comment - additional comments and annotations
From BioAssay Depositor:
Assay Type: Binding
Assay Data Source: Scientific Literature
Result Definitions
TIDNameDescriptionHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1Km*Km PubChem standard valueFloatμM
2Km activity commentKm activity commentString
3Km standard flagKm standard flagInteger
4Km qualifierKm qualifierString
5Km published valueKm published valueFloatμM
6Km standard valueKm standard valueFloatnM

* Activity Concentration.

Data Table (Concise)
Data Table ( Complete ):     View Active Data    View All Data
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